Recent advances in hepatocellular carcinoma therapy

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Recent advances in hepatocellular carcinoma therapy is …
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scholarly articleQ13442814

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P356DOI10.1016/J.PHARMTHERA.2017.02.010
P8608Fatcat IDrelease_qeatk3wwbvazrpx3rnzqzafsci
P932PMC publication ID5777523
P698PubMed publication ID28174094

P2093author name stringRam I Mahato
Rinku Dutta
P2860cites workMicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenibQ24655048
Diagnostics and Treatment of Hepatocellular Carcinoma in 2016: Standards and DevelopmentsQ26740315
New advances in hepatocellular carcinomaQ26749329
Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific RegionQ26750444
Recent Advances in Antiviral Therapy for Chronic Hepatitis CQ26750476
Hepatocellular carcinoma: Where are we?Q26765182
MicroRNAs as Biomarkers for Liver Disease and Hepatocellular CarcinomaQ26765476
Glypican-3 is a prognostic factor and an immunotherapeutic target in hepatocellular carcinomaQ26772321
Systemic therapies for hepatocellular carcinomaQ26775193
Nanoparticles for targeted delivery of therapeutics and small interfering RNAs in hepatocellular carcinomaQ26823523
miR-122 is a unique molecule with great potential in diagnosis, prognosis of liver disease, and therapy both as miRNA mimic and antimirQ26991956
Human occludin is a hepatitis C virus entry factor required for infection of mouse cellsQ27490169
Management of hepatocellular carcinoma: An updateQ27860530
Immunotherapy of hepatocellular carcinoma: Unique challenges and clinical opportunitiesQ42024872
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC developmentQ42199386
Therapeutic potential of small interfering RNAs/micro interfering RNA in hepatocellular carcinomaQ42434482
A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C.Q42989841
Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodiesQ43041465
Targeting hepatic cancer cells with pegylated dendrimers displaying N-acetylgalactosamine and SP94 peptide ligandsQ43845180
[Clinical value of iodine [131I] metuximab infusion combined with TACE for treatment of patients with post-intervention relapse of mid or advanced stage hepatocellular carcinoma].Q44267804
A phase II trial of bevacizumab plus temsirolimus in patients with advanced hepatocellular carcinomaQ44930012
Brivanib in patients with advanced hepatocellular carcinoma who were intolerant to sorafenib or for whom sorafenib failed: results from the randomized phase III BRISK-PS study.Q45980006
SEARCH: a phase III, randomized, double-blind, placebo-controlled trial of sorafenib plus erlotinib in patients with advanced hepatocellular carcinoma.Q50454368
Phase I trial of multidrug resistance-associated protein 3-derived peptide in patients with hepatocellular carcinoma.Q50712098
Carboxymethyl Dextran-Stabilized Polyethylenimine-Poly(epsilon-caprolactone) Nanoparticles-Mediated Modulation of MicroRNA-34a Expression via Small-Molecule Modulator for Hepatocellular Carcinoma Therapy.Q50798066
iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafenib to enhance anti-hepatocellular carcinoma efficacy.Q50870799
mRECIST response combined with sorafenib-related adverse events is superior to either criterion alone in predicting survival in HCC patients treated with TACE plus sorafenib.Q51452386
Metronomic S-1 chemotherapy plus transcatheter arterial chemoembolization (TACE): a promising treatment of hepatocellular carcinoma refractory to TACE.Q51789583
Tumor pH(e)-triggered charge-reversal and redox-responsive nanoparticles for docetaxel delivery in hepatocellular carcinoma treatment.Q52918204
Low miR-29c expression is a prognostic marker in hepatocellular carcinoma.Q53036075
Randomized phase II placebo controlled study of codrituzumab in previously treated patients with advanced hepatocellular carcinoma.Q53162619
Mouse homologue of a novel human oncofetal antigen, glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in miceQ81208649
Circulating microRNA-21 as a novel biomarker for hepatocellular carcinomaQ84546774
Hepatocellular carcinomaQ85238211
Liposomes for targeting hepatocellular carcinoma: use of conjugated arabinogalactan as targeting ligandQ85774171
Multilayer-Coated Liquid Crystalline Nanoparticles for Effective Sorafenib Delivery to Hepatocellular CarcinomaQ86021332
Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinomaQ28118779
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entryQ28131832
Aptamer-functionalized peptide H3CR5C as a novel nanovehicle for codelivery of fasudil and miRNA-195 targeting hepatocellular carcinomaQ28829736
Claudin association with CD81 defines hepatitis C virus entry.Q29465808
Hepatocellular carcinoma pathogenesis: from genes to environmentQ29615767
Hepatitis C virus cell entry: a target for novel antiviral strategies to address limitations of direct acting antivirals.Q30386551
Sunitinib versus sorafenib in advanced hepatocellular cancer: results of a randomized phase III trialQ33410643
Ramucirumab versus placebo as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib (REACH): a randomised, double-blind, multicentre, phase 3 trialQ33423800
131I-Labeled-Metuximab Plus Transarterial Chemoembolization in Combination Therapy for Unresectable Hepatocellular Carcinoma: Results from a Multicenter Phase IV Clinical StudyQ33428038
Phase I study of PF-03446962, a fully human monoclonal antibody against activin receptor-like kinase-1, in patients with hepatocellular carcinoma.Q33433311
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cellsQ33847621
Hepatocellular carcinoma: novel molecular targets in carcinogenesis for future therapiesQ33895113
Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factorQ34245963
In vivo activity of nuclease-resistant siRNAsQ34365687
Elimination pathways of systemically delivered siRNA.Q34556940
Effect of everolimus on survival in advanced hepatocellular carcinoma after failure of sorafenib: the EVOLVE-1 randomized clinical trialQ34663499
Mammalian ABC transporters in health and diseaseQ34667449
Linifanib versus Sorafenib in patients with advanced hepatocellular carcinoma: results of a randomized phase III trialQ34786090
Japanese phase I study of GC33, a humanized antibody against glypican-3 for advanced hepatocellular carcinomaQ35051445
Chemopreventive strategies in hepatocellular carcinomaQ35101365
Immunotherapy for hepatocellular carcinoma: From basic research to clinical use.Q35567765
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers.Q35779648
Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC.Q35824254
Targeted delivery of chemically modified anti-miR-221 to hepatocellular carcinoma with negatively charged liposomesQ35914942
Novel Glypican-3-Binding Peptide for in Vivo Hepatocellular Carcinoma Fluorescent ImagingQ35916218
Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitroQ35939788
Lactoferrin-modified PEGylated liposomes loaded with doxorubicin for targeting delivery to hepatocellular carcinomaQ35965943
Hepatocellular carcinoma: molecular pathways and new therapeutic targets.Q36140308
Phase II Study of Personalized Peptide Vaccination with Both a Hepatitis C Virus-Derived Peptide and Peptides from Tumor-Associated Antigens for the Treatment of HCV-Positive Advanced Hepatocellular Carcinoma PatientsQ36204431
Serum exosomal microRNAs as novel biomarkers for hepatocellular carcinomaQ36294432
Lactosylated liposomes for targeted delivery of doxorubicin to hepatocellular carcinomaQ36334145
Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver diseaseQ36402141
Folate receptor-targeted liposomes loaded with a diacid metabolite of norcantharidin enhance antitumor potency for H22 hepatocellular carcinoma both in vitro and in vivoQ36798011
Peptide vaccines for hepatocellular carcinomaQ36888010
Relation between microRNAs and Apoptosis in Hepatocellular CarcinomaQ36945012
Systemic treatment for advanced hepatocellular carcinoma: the search of new agents to join sorafenib in the effective therapeutic armamentarium.Q38824017
Visualization of hepatitis B virus entry - novel tools and approaches to directly follow virus entry into hepatocytesQ38826563
Advanced Hepatocellular Cancer: the Current State of Future ResearchQ38848537
Glycyrrhetinic Acid-Mediated Polymeric Drug Delivery Targeting the Acidic Microenvironment of Hepatocellular CarcinomaQ38856193
The promotion of salinomycin delivery to hepatocellular carcinoma cells through EGFR and CD133 aptamers conjugation by PLGA nanoparticlesQ38857110
Cell death-inducing DFFA-like effector b is required for hepatitis C virus entry into hepatocytesQ38994889
Overexpression of GPC3 inhibits hepatocellular carcinoma cell proliferation and invasion through induction of apoptosisQ39206940
MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinomaQ39414132
iRGD-Decorated Polymeric Nanoparticles for the Efficient Delivery of Vandetanib to Hepatocellular Carcinoma: Preparation and in Vitro and in Vivo EvaluationQ39629173
Hepatocellular carcinoma cell-specific peptide ligand for targeted drug deliveryQ40001445
Downregulation of microRNA-122 promotes proliferation, migration, and invasion of human hepatocellular carcinoma cells by activating epithelial-mesenchymal transitionQ40039824
Identification of HLA-A2- or HLA-A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy of hepatocellular carcinomaQ40283613
RGD peptide targeted lipid coated nanoparticles for combinatorial delivery of sorafenib and quercetin against hepatocellular carcinomaQ40688909
Effect of integrin receptor-targeted liposomal paclitaxel for hepatocellular carcinoma targeting and therapyQ41110002
Association of nonalcoholic fatty liver disease (NAFLD) with hepatocellular carcinoma (HCC) in the United States from 2004 to 2009.Q41482573
Identification of transferrin receptor 1 as a hepatitis C virus entry factorQ36967731
Novel approaches to treatment of hepatocellular carcinoma and hepatic metastases using thermal ablation and thermosensitive liposomes.Q37083651
Investigation of SP94 Peptide as a Specific Probe for Hepatocellular Carcinoma Imaging and TherapyQ37271850
Evolving therapies in the treatment of hepatocellular carcinomaQ37290714
Fate of fat: the role of adipose triglyceride lipase in lipolysisQ37326006
Multimodal approaches to the treatment of hepatocellular carcinomaQ37384682
Targeted therapy for hepatocellular carcinomaQ37504684
Circulating microRNA profiles in plasma: identification of miR-224 as a novel diagnostic biomarker in hepatocellular carcinoma independent of hepatic functionQ37619833
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic applicationQ37665303
A fresh look at NASH pathogenesis. Part 1: the metabolic movers.Q37759155
Sterile inflammation in the liverQ38043897
Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyondQ38214522
Physiological roles of asialoglycoprotein receptors (ASGPRs) variants and recent advances in hepatic-targeted delivery of therapeutic molecules via ASGPRsQ38224292
Macrophages, immunity, and metabolic diseaseQ38230879
Hepatocellular carcinoma and microRNA: new perspectives on therapeutics and diagnosticsQ38275679
Significant biomarkers for the management of hepatocellular carcinomaQ38412315
Tivantinib (ARQ197) in hepatocellular carcinomaQ38513062
Novel drugs in clinical development for hepatocellular carcinomaQ38537138
Hepatocellular Carcinoma: A Phase II Randomized Controlled Double-Blind Trial of Transarterial Chemoembolization in Combination with Biweekly Intravenous Administration of Bevacizumab or a PlaceboQ38541397
Oncogenic signaling pathways and origins of tumor-initiating stem-like cells of hepatocellular carcinomas induced by hepatitis C virus, alcohol and/or obesity.Q38552480
Immunological landscape and immunotherapy of hepatocellular carcinomaQ38611895
Status of and prospects for cancer vaccines against hepatocellular carcinoma in clinical trialsQ38621919
Progress in the development of vaccines for hepatitis C virus infectionQ38635596
Glycyrrhetinic Acid Mediated Drug Delivery Carriers for Hepatocellular Carcinoma Therapy.Q38710684
A Review and Update of Treatment Options and Controversies in the Management of Hepatocellular CarcinomaQ38712688
Hepatocellular Carcinoma in Obesity, Type 2 Diabetes, and NAFLD.Q38752448
Circulating microRNAs in Hepatocellular Carcinoma: Potential Diagnostic and Prognostic BiomarkersQ38758317
Design of cholesterol arabinogalactan anchored liposomes for asialoglycoprotein receptor mediated targeting to hepatocellular carcinoma: In silico modeling, in vitro and in vivo evaluationQ38768210
Targeted hepatocellular carcinoma therapy: transferrin modified, self-assembled polymeric nanomedicine for co-delivery of cisplatin and doxorubicinQ38788994
Mechanisms of HBV-induced hepatocellular carcinoma.Q38809557
Vaccination with liposome-coupled glypican-3-derived epitope peptide stimulates cytotoxic T lymphocytes and inhibits GPC3-expressing tumor growth in miceQ38816046
Doxorubicin-transferrin conjugate triggers pro-oxidative disorders in solid tumor cells.Q38816743
Targeted Therapy for Hepatocellular CarcinomaQ38822106
Pathogenesis of alcoholic liver diseaseQ38823745
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)106-117
P577publication date2017-02-04
P1433published inPharmacology & TherapeuticsQ3378596
P1476titleRecent advances in hepatocellular carcinoma therapy
P478volume173

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