Melatonin in type 2 diabetes mellitus and obesity

scientific article published on 01 February 2019

Melatonin in type 2 diabetes mellitus and obesity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41574-018-0130-1
P698PubMed publication ID30531911

P2093author name stringRalf Jockers
Angeliki Karamitri
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Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traitsQ51351265
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Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment.Q55248558
Genetic variations of the melatonin pathway in patients with attention-deficit and hyperactivity disordersQ57093573
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Melatonin shifts human circadian rhythms according to a phase-response curveQ34253161
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolismQ34281205
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathwaysQ34355379
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.Q34384945
Effects of Genetic Variants Previously Associated with Fasting Glucose and Insulin in the Diabetes Prevention ProgramQ34415887
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility lociQ34501150
Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-AmericansQ34641320
Melatonin receptors: role on sleep and circadian rhythm regulationQ34716949
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretionQ34897184
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes riskQ34897205
Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 childrenQ35043398
Sensitization: a mechanism for melatonin action in the pars tuberalisQ35080127
Distribution, function and physiological role of melatonin in the lower gut.Q35404204
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Deletion of GαZ Protein Protects against Diet-induced Glucose Intolerance via Expansion of β-Cell MassQ36016914
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Association of Type 2 Diabetes Susceptibility Loci With One‐Year Weight Loss in the Look AHEAD Clinical TrialQ36120556
Association Study with 77 SNPs Confirms the Robust Role for the rs10830963/G of MTNR1B Variant and Identifies Two Novel Associations in Gestational Diabetes Mellitus DevelopmentQ36245625
GIRK Channels Mediate the Nonphotic Effects of Exogenous MelatoninQ36272497
Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretionQ36345553
Common genetic variants differentially influence the transition from clinically defined states of fasting glucose metabolismQ36661586
Melatonin and pancreatic islets: interrelationships between melatonin, insulin and glucagonQ36820392
Common type 2 diabetes risk variant in MTNR1B worsens the deleterious effect of melatonin on glucose tolerance in humansQ36867614
Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology.Q36930753
Mitochondria Synthesize Melatonin to Ameliorate Its Function and Improve Mice Oocyte's Quality under in Vitro Conditions.Q37050785
The genetics of gestational diabetes mellitus: evidence for relationship with type 2 diabetes mellitusQ37139067
Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetesQ37173576
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 EuropeansQ37193733
Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin responseQ37259911
P433issue2
P921main subjecttype 2 diabetesQ3025883
P304page(s)105-125
P577publication date2019-02-01
P1433published inNature Reviews EndocrinologyQ2079257
P1476titleMelatonin in type 2 diabetes mellitus and obesity
P478volume15

Reverse relations

cites work (P2860)
Q91749495A functional polymorphism rs10830963 in melatonin receptor 1B associated with the risk of gestational diabetes mellitus
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Q91900049The circadian regulation of food intake

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