Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy

scientific article published on 22 December 2018

Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.30190
P932PMC publication ID6590289
P698PubMed publication ID30033593

P50authorJan-Georg WojtyniakQ60320130
Angelika VollmarQ21253616
P2093author name stringMartin Müller
Melanie Ulrich
Georg J Arnold
Thomas Fröhlich
Doris Mayr
Stefan Zahler
Giorgio Scita
Alexander Gerbes
Simon Rothenfußer
Thorsten Lehr
Johanna Pachmayr
Maximilian A Ardelt
Dario Parazzoli
Lars König
Carina Atzberger
Veronika Kanitz
Emanuele Martini
Martina Meßner
Laura Posselt
Petra Cantonati
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Dinaciclib, a novel CDK inhibitor, demonstrates encouraging single-agent activity in patients with relapsed multiple myeloma.Q33418705
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Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.Q33907588
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Cdk5 behind the wheel: a role in trafficking and transport?Q34537614
Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cellsQ34681633
Linifanib versus Sorafenib in patients with advanced hepatocellular carcinoma: results of a randomized phase III trialQ34786090
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c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinomaQ35235798
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.Q35250612
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Cdk5 regulates multiple cellular events in neural development, function and disease.Q38213140
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Epithelial-to-Mesenchymal Plasticity Harnesses Endocytic CircuitriesQ38376446
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Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trialQ38785510
P433issue1
P304page(s)376-393
P577publication date2018-12-22
P1433published inHepatologyQ15724398
P1476titleInhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy
P478volume69

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cites work (P2860)
Q92475195A kinase of many talents: non-neuronal functions of CDK5 in development and disease
Q93185953CDK5 neutralizes the tumor suppressing effect of BIN1 via mediating phosphorylation of c-MYC at Ser-62 site in NSCLC
Q64388096CRISPR/Cas9 for overcoming drug resistance in solid tumors
Q89998270From bench to bed: the tumor immune microenvironment and current immunotherapeutic strategies for hepatocellular carcinoma
Q89528234New landscapes and horizons in hepatocellular carcinoma therapy
Q90333546Potent Activity of Composite Cyclin Dependent Kinase Inhibition against Hepatocellular Carcinoma

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