Plasma Levels of the Bioactive Sphingolipid Metabolite S1P in Adult Cystic Fibrosis Patients: Potential Target for Immunonutrition?

scientific article published on 14 March 2020

Plasma Levels of the Bioactive Sphingolipid Metabolite S1P in Adult Cystic Fibrosis Patients: Potential Target for Immunonutrition? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/NU12030765
P932PMC publication ID7146441
P698PubMed publication ID32183316

P50authorKonrad HoetzeneckerQ38640028
Burkhard KleuserQ59916784
Michael TraunerQ62560551
Eva UntersmayrQ88238661
Emina HalilbasicQ90399354
Peter JakschQ90399357
P2093author name stringLili Kazemi-Shirazi
Lukasz Japtok
Denise Heiden
Elisabeth Fuerst
Askin Kulu
Susanne C Diesner
P2860cites workExport of sphingosine-1-phosphate and cancer progressionQ27009557
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein MQ27667968
Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphateQ28205285
Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseasesQ28265044
Structure and function of the CFTR chloride channelQ28295591
World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjectsQ28300546
Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) ActivityQ28548390
Sphingosine-1-phosphate: an enigmatic signalling lipidQ29620563
Immunonutrition in patients with cyctic fibrosis leads to drop of serum amyloid A and increase of oxidative stressQ33751136
Sphingosine 1-phosphate modulates antigen capture by murine Langerhans cells via the S1P2 receptor subtypeQ34474499
Ozanimod Induction and Maintenance Treatment for Ulcerative ColitisQ34524946
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosisQ34765872
Sphingolipid metabolites in inflammatory diseaseQ35061720
CFTR and sphingolipids mediate hypoxic pulmonary vasoconstrictionQ35279508
Sphingosine-1-phosphate signaling and its role in diseaseQ35661485
Sources, metabolism, and regulation of circulating sphingosine-1-phosphateQ35776618
Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxisQ36151548
Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxisQ36399383
Low sphingosine-1-phosphate impairs lung dendritic cells in cystic fibrosisQ36703926
The alliance of sphingosine-1-phosphate and its receptors in immunityQ37010807
Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signalingQ37173184
Sphingosine-1-phosphate receptor-1 (S1P1) is expressed by lymphocytes, dendritic cells, and endothelium and modulated during inflammatory bowel diseaseQ37317783
Lipid metabolism in cystic fibrosisQ37390419
Prevalence of dyslipidemia in adults with cystic fibrosisQ37624200
Lipids in cystic fibrosisQ37920895
The role of sphingolipids in respiratory diseaseQ37928817
Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activationQ38346649
Cystic fibrosis from the gastroenterologist's perspectiveQ38704228
Ceramide mediates lung fibrosis in cystic fibrosisQ39884057
Serum Lipoprotein Concentrations in Cystic FibrosisQ40126324
Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humansQ41979804
Lipoprotein patterns in adult cystic fibrosis: a cause for concern or marker for survival?Q42960756
Therapeutic efficacy and safety of amitriptyline in patients with cystic fibrosis.Q45933447
Targeting S1P Receptors, A New Mechanism of Action for Inflammatory Bowel Disease Therapy.Q46035910
Dietary and Endogenous Sphingolipid Metabolism in Chronic InflammationQ47170906
Tumor necrosis factor-α-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failureQ48548660
Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931.Q48678102
Erythrocytes store and release sphingosine 1-phosphate in blood.Q51084957
Relationship of decreased hepatic lipase activity and lipoprotein abnormalities to essential fatty acid deficiency in cystic fibrosis patientsQ69701881
Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serumQ73436742
Role of CD95 in pulmonary inflammation and infection in cystic fibrosisQ83400699
Therapy of CF-patients with amitriptyline and placebo--a randomised, double-blind, placebo-controlled phase IIb multicenter, cohort-studyQ86568123
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P921main subjectcystic fibrosisQ178194
sphingolipidsQ410395
P577publication date2020-03-14
P1433published inNutrientsQ7070485
P1476titlePlasma Levels of the Bioactive Sphingolipid Metabolite S1P in Adult Cystic Fibrosis Patients: Potential Target for Immunonutrition?
P478volume12