| scholarly article | Q13442814 |
| P50 | author | Kazuaki Takabe | Q41089558 |
| P2093 | author name string | Sarah Spiegel | |
| P2860 | cites work | Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases | Q24311877 |
| Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2 | Q24336131 | ||
| Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling | Q24337047 | ||
| The role of sphingosine-1-phosphate transporter Spns2 in immune system function | Q24599540 | ||
| Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation | Q24629370 | ||
| Role of ABCC1 in export of sphingosine-1-phosphate from mast cells | Q24671687 | ||
| Principles of bioactive lipid signalling: lessons from sphingolipids | Q28265743 | ||
| The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice | Q28588851 | ||
| Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network | Q28591658 | ||
| STATs in cancer inflammation and immunity: a leading role for STAT3 | Q29547203 | ||
| Accessories to the crime: functions of cells recruited to the tumor microenvironment | Q29620161 | ||
| Sphingosine-1-phosphate: an enigmatic signalling lipid | Q29620563 | ||
| S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites. | Q30514214 | ||
| Discovery and evaluation of inhibitors of human sphingosine kinase | Q31004970 | ||
| Vascular endothelium as a contributor of plasma sphingosine 1-phosphate | Q33378571 | ||
| Fluid shear stress enhances the sphingosine 1-phosphate responses in cell-cell interactions between platelets and endothelial cells | Q80356980 | ||
| FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1. | Q33422807 | ||
| Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning | Q33615222 | ||
| Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. | Q33773569 | ||
| Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2. | Q33796082 | ||
| Sphingosine kinase 1 in cancer | Q33853998 | ||
| Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro. | Q34017124 | ||
| Lymphangiogenesis: A new player in cancer progression | Q34084937 | ||
| Sphingosine 1-phosphate and cancer | Q34121255 | ||
| Sphingolipid transport: rafts and translocators. | Q34128462 | ||
| The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720. | Q34150336 | ||
| Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis. | Q34251293 | ||
| Regulation of limb development by the sphingosine 1-phosphate receptor S1p1/EDG-1 occurs via the hypoxia/VEGF axis. | Q34310949 | ||
| Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells | Q34314035 | ||
| Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond | Q34364844 | ||
| Role of sphingosine kinase 2 in cell migration toward epidermal growth factor | Q34425898 | ||
| Sphingosine‐1‐phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration | Q34502695 | ||
| Functions of the multifaceted family of sphingosine kinases and some close relatives | Q34585774 | ||
| "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets | Q34593159 | ||
| The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors | Q34901297 | ||
| STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors. | Q34936215 | ||
| Neural crest-derived pericytes promote egress of mature thymocytes at the corticomedullary junction | Q35022130 | ||
| The MRP family of drug efflux pumps | Q35567296 | ||
| Biologically active sphingolipids in cancer pathogenesis and treatment | Q35852313 | ||
| The outs and the ins of sphingosine-1-phosphate in immunity | Q36011196 | ||
| Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1 | Q36117441 | ||
| S1PR1 is an effective target to block STAT3 signaling in activated B cell-like diffuse large B-cell lymphoma. | Q36177932 | ||
| Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development | Q36236992 | ||
| Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis. | Q36386459 | ||
| Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation | Q36530007 | ||
| High expression of ATP-binding cassette transporter ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survival | Q36576187 | ||
| Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer. | Q36627430 | ||
| Mrp1 is essential for sphingolipid signaling to p-glycoprotein in mouse blood-brain and blood-spinal cord barriers | Q36655374 | ||
| Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways | Q36835075 | ||
| Sphingosine-1-phosphate and interleukin-1 independently regulate plasminogen activator inhibitor-1 and urokinase-type plasminogen activator receptor expression in glioblastoma cells: implications for invasiveness | Q36982983 | ||
| Role for sphingosine kinase 1 in colon carcinogenesis. | Q37072425 | ||
| A novel method to quantify sphingosine 1-phosphate by immobilized metal affinity chromatography (IMAC). | Q37106169 | ||
| Targeting sphingosine kinase 1 inhibits Akt signaling, induces apoptosis, and suppresses growth of human glioblastoma cells and xenografts | Q37364840 | ||
| Characterization of the ATP-dependent sphingosine 1-phosphate transporter in rat erythrocytes | Q37371999 | ||
| K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5. | Q37686404 | ||
| Regulation of sphingosine kinase and sphingolipid signaling. | Q37792598 | ||
| Extracellular and intracellular sphingosine-1-phosphate in cancer. | Q37946282 | ||
| Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs | Q37965743 | ||
| Angiopoietin-2: an attractive target for improved antiangiogenic tumor therapy | Q38087230 | ||
| Sphingosine kinase-1 enhances resistance to apoptosis through activation of PI3K/Akt/NF-κB pathway in human non-small cell lung cancer | Q38411992 | ||
| Clinical significance of sphingosine kinase-1 expression in human astrocytomas progression and overall patient survival | Q38424345 | ||
| ATP-binding cassette ABCC1 is involved in the release of sphingosine 1-phosphate from rat uterine leiomyoma ELT3 cells and late pregnant rat myometrium | Q39497978 | ||
| The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate | Q39589659 | ||
| Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients | Q39881982 | ||
| Recycling of sphingosine is regulated by the concerted actions of sphingosine-1-phosphate phosphohydrolase 1 and sphingosine kinase 2. | Q40076316 | ||
| Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages | Q40306295 | ||
| Sphingosine kinase 1 is up-regulated in colon carcinogenesis | Q40345686 | ||
| Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells | Q40367377 | ||
| Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines | Q40384186 | ||
| The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish. | Q42551908 | ||
| Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate | Q42556020 | ||
| Sphingosine 1-phosphate receptors and sphingosine kinase 1: novel biomarkers for clinical prognosis in breast, prostate, and hematological cancers | Q42593194 | ||
| Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer. | Q42638803 | ||
| Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens | Q42805681 | ||
| SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism | Q42810891 | ||
| Sphingosine kinase-1 activity and expression in human prostate cancer resection specimens | Q42849747 | ||
| Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphate | Q43148560 | ||
| The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2. | Q43563466 | ||
| Critical role of ABCA1 transporter in sphingosine 1-phosphate release from astrocytes | Q44091518 | ||
| Sphingosine kinase transmits estrogen signaling in human breast cancer cells. | Q44526063 | ||
| Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720. | Q45086529 | ||
| Involvement of the ABC-transporter ABCC1 and the sphingosine 1-phosphate receptor subtype S1P(3) in the cytoprotection of human fibroblasts by the glucocorticoid dexamethasone | Q46049440 | ||
| Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate | Q46494392 | ||
| Immunohistochemical distribution of sphingosine kinase 1 in normal and tumor lung tissue | Q46516547 | ||
| Sphingosine kinase 1 protein and mRNA are overexpressed in non-Hodgkin lymphomas and are attractive targets for novel pharmacological interventions | Q46615363 | ||
| Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner | Q46863524 | ||
| S1P1 inhibits sprouting angiogenesis during vascular development | Q47073640 | ||
| Modulation of P-glycoprotein function by sphingosine kinase-1 in brain endothelial cells | Q48266093 | ||
| Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors. | Q50718278 | ||
| Erythrocytes store and release sphingosine 1-phosphate in blood. | Q51084957 | ||
| Sphingosine kinase 1 overexpression is regulated by signaling through PI3K, AKT2, and mTOR in imatinib-resistant chronic myeloid leukemia cells. | Q53289280 | ||
| Metabolism and functional effects of sphingolipids in blood cells | Q73231016 | ||
| Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum | Q73436742 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1839-1846 | |
| P577 | publication date | 2014-09-01 | |
| P1433 | published in | Journal of Lipid Research | Q6295449 |
| P1476 | title | Export of sphingosine-1-phosphate and cancer progression | |
| P478 | volume | 55 |
| Q52663621 | ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer. |
| Q37662151 | An oncogenic role for sphingosine kinase 2. |
| Q36405432 | Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase |
| Q41638170 | Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase. |
| Q57128749 | Bile acids as global regulators of hepatic nutrient metabolism |
| Q64101121 | Bioactive sphingolipid profile in a xenograft mouse model of head and neck squamous cell carcinoma |
| Q41089511 | Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis |
| Q64904602 | Ceramide and Exosomes: A Novel Target in Cancer Biology and Therapy. |
| Q41622885 | Clinical Impact of Sphingosine-1-Phosphate in Breast Cancer |
| Q61701703 | Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma |
| Q58772957 | Diffuse Gastric Cancer: A Summary of Analogous Contributing Factors for Its Molecular Pathogenicity |
| Q57043989 | Dihydro-sphingosine 1-phosphate interacts with carrier proteins in a manner distinct from that of sphingosine 1-phosphate |
| Q40994197 | Distinct mechanisms of B and T lymphocyte accumulation generate tumor-draining lymph node hypertrophy |
| Q45071199 | Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer. |
| Q62083308 | Dysregulation of Sphingolipid Metabolism in Melanoma: Roles in Pigmentation, Cell Survival and Tumor Progression |
| Q92823174 | Emerging therapeutic targets associated with the immune system in patients with intracerebral haemorrhage (ICH): From mechanisms to translation |
| Q36579672 | Extracellular Matrix Rigidity-dependent Sphingosine-1-phosphate Secretion Regulates Metastatic Cancer Cell Invasion and Adhesion |
| Q38723015 | Genome-wide in vivo screen identifies novel host regulators of metastatic colonization |
| Q40567317 | Host sphingosine kinase 1 worsens pancreatic cancer peritoneal carcinomatosis |
| Q36898368 | Implication of sphingosin-1-phosphate in cardiovascular regulation |
| Q52647500 | Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human. |
| Q37100281 | Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods |
| Q55020615 | Intravital microscopy in the study of the tumor microenvironment: from bench to human application. |
| Q88550889 | Iron excess upregulates SPNS2 mRNA levels but reduces sphingosine-1-phosphate export in human osteoblastic MG-63 cells |
| Q43204687 | Ketone strong: emerging evidence for a therapeutic role of ketone bodies in neurological and neurodegenerative diseases |
| Q93365978 | Lipid transporter Spns2 promotes microglia pro-inflammatory activation in response to amyloid-beta peptide |
| Q64884687 | Lysophospholipids in laboratory medicine. |
| Q33829692 | Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget |
| Q38720294 | Metastatic triple-negative breast cancer is dependent on SphKs/S1P signaling for growth and survival |
| Q37649145 | Mouse genomic screen reveals novel host regulator of metastasis |
| Q45073187 | Paradoxical Association of Postoperative Plasma Sphingosine-1-Phosphate with Breast Cancer Aggressiveness and Chemotherapy. |
| Q42220023 | Photoswitchable phospholipid FRET acceptor: Detergent free intermembrane transfer assay of fluorescent lipid analogs. |
| Q90399362 | Plasma Levels of the Bioactive Sphingolipid Metabolite S1P in Adult Cystic Fibrosis Patients: Potential Target for Immunonutrition? |
| Q38829760 | Resveratrol exerts a biphasic effect on apolipoprotein M. |
| Q26996672 | Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy |
| Q92009926 | Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma |
| Q91738678 | Roles of sphingosine-1-phosphate signaling in cancer |
| Q89587308 | S1P Signaling in the Tumor Microenvironment |
| Q42735904 | S1P promotes breast cancer progression by angiogenesis and lymphangiogenesis |
| Q35061720 | Sphingolipid metabolites in inflammatory disease |
| Q38332040 | Sphingolipids and mitochondrial apoptosis |
| Q47112312 | Sphingosine 1-phosphate (S1P) signaling in glioblastoma multiforme-A systematic review. |
| Q57471571 | Sphingosine kinase 1 activation by estrogen receptor α36 contributes to tamoxifen resistance in breast cancer |
| Q46726983 | Sphingosine kinase 1/sphingosine-1-phosphate (S1P)/S1P receptor axis is involved in ovarian cancer angiogenesis |
| Q39376014 | Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology |
| Q91877735 | Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling |
| Q26766425 | Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential |
| Q89552038 | Sphingosine-1-Phosphate in the Tumor Microenvironment: A Signaling Hub Regulating Cancer Hallmarks |
| Q40764980 | Sphingosine-1-phosphate and its effect on glucose deprivation/glucose reload stress: from gene expression to neuronal survival |
| Q42181059 | Sphingosine-1-phosphate transporters as targets for cancer therapy. |
| Q50665340 | Sphingosine-1-phosphate/sphingosine kinase 1-dependent lymph node metastasis in esophageal squamous cell carcinoma. |
| Q36299860 | Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases |
| Q47851281 | Targeting the SphK1/S1P/S1PR1 axis that links obesity, chronic inflammation and breast cancer metastasis. |
| Q92446113 | Targeting the Sphingolipid System as a Therapeutic Direction for Glioblastoma |
| Q61450263 | The Role of S1P and the Related Signaling Pathway in the Development of Tissue Fibrosis |
| Q47130227 | The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer. |
| Q26748927 | The emerging role of FTY720 (Fingolimod) in cancer treatment |
| Q45051424 | The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice |
| Q57153732 | The role of sphingosine-1-phosphate in inflammation and cancer progression |
| Q38734489 | The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications. |
| Q38909010 | The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. |
| Q43076657 | Upregulation of ABC transporters contributes to chemoresistance of sphingosine 1-phosphate lyase-deficient fibroblasts. |
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