scholarly article | Q13442814 |
P2093 | author name string | H Zhang | |
S Spiegel | |||
T Seki | |||
A Olivera | |||
G Brooker | |||
N N Desai | |||
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Metabolism of sphingosine bases. 13. Enzymatic synthesis of 1-phosphate esters of 4t-sphingenine (sphingosine), sphinganine (dihydrosphingosine), 4-hydroxysphinganine (phytosphingosine) and 3-dehydrosphinganine by erythrocytes. | Q53782925 | ||
A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis | Q68544672 | ||
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Enzymatic Formation of Dihydrosphingosine 1-Phosphate | Q71473185 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 13 | |
P304 | page(s) | 155-167 | |
P577 | publication date | 1991-07-01 | |
P1433 | published in | Journal of Cell Biology | Q1524550 |
P1476 | title | Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation | |
P478 | volume | 114 |
Q34593159 | "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets |
Q37305365 | 1-O-acylceramides are natural components of human and mouse epidermis |
Q44927619 | A novel approach for preventing esophageal stricture formation: sphingosylphosphorylcholine-enhanced tissue remodeling |
Q42804390 | ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3'-kinase through an extracellular site. Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate |
Q47947326 | Aberrant sphingolipid metabolism in the human fallopian tube with ectopic pregnancy |
Q39215469 | Ablation of sphingosine kinase-2 inhibits tumor cell proliferation and migration |
Q41989817 | Accumulation of phosphorylated sphingoid long chain bases results in cell growth inhibition in Saccharomyces cerevisiae |
Q42992854 | Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells |
Q41151107 | Adiponectin and its Hydrolase-Activated Receptors |
Q27310161 | Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain |
Q45129798 | Altered de novo sphingolipid biosynthesis is involved in the serum deprivation-induced cell death in LLC-PK1 cells |
Q58604755 | An update on sphingosine-1-phosphate receptor 1 modulators |
Q73186728 | Analysis of ceramide 1-phosphate and sphingosine-1-phosphate phosphatase activities |
Q39494222 | Analysis of phosphorylated sphingolipid long-chain bases reveals potential roles in heat stress and growth control in Saccharomyces. |
Q73186722 | Assaying sphingosine kinase activity |
Q78428565 | B-5354a, b and c, New Sphingosine Kinase Inhibitors, Produced by a Marine Bacterium. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Structure Determination. |
Q37396760 | Beyond the cherry-red spot: Ocular manifestations of sphingolipid-mediated neurodegenerative and inflammatory disorders |
Q37141279 | Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening. |
Q70870850 | Biosynthesis of N-acetylsphingosine by platelet-activating factor: sphingosine CoA-independent transacetylase in HL-60 cels |
Q41199299 | Ca2+ mobilizing action of sphingosine in Jurkat human leukemia T cells. Evidence that sphingosine releases Ca2+ from inositol trisphosphate- and phosphatidic acid-sensitive intracellular stores through a mechanism independent of inositol trisphospha |
Q71737267 | Calcium signalling by G protein-coupled sphingolipid receptors in bovine aortic endothelial cells |
Q42830058 | Cell cycle arrest induced by an inhibitor of glucosylceramide synthase. Correlation with cyclin-dependent kinases |
Q24653552 | Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate |
Q46400730 | Ceramide 1-phosphate phosphatase activity in brain |
Q73186716 | Ceramide kinase |
Q35084457 | Ceramide structure predicts tumor ganglioside immunosuppressive activity |
Q35740323 | Ceramide-1-phosphate: a novel regulator of cell activation |
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Q28483643 | Characterization of isoenzyme-selective inhibitors of human sphingosine kinases |
Q42805853 | Cis-4-methylsphingosine phosphate induces apoptosis in neuroblastoma cells by opposite effects on p38 and ERK mitogen-activated protein kinases |
Q24319856 | Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling? |
Q44433921 | Correlation of S1P1 and ERp29 expression to progression, metastasis, and poor prognosis of gallbladder adenocarcinoma |
Q27644028 | Crystal structure of YegS, a homologue to the mammalian diacylglycerol kinases, reveals a novel regulatory metal binding site |
Q36764024 | Current perspectives on FTY720. |
Q39835135 | Decrease of Tau hyperphosphorylation by 17β estradiol requires sphingosine kinase in a glutamate toxicity model. |
Q40755466 | Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein |
Q44009044 | Delayed ERK activation by ceramide reduces melanin synthesis in human melanocytes |
Q30417604 | Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors |
Q38335935 | Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes |
Q41932606 | Differential Roles of de Novo Sphingolipid Biosynthesis and Turnover in the “Burst” of Free Sphingosine and Sphinganine, and Their 1-Phosphates and N-Acyl-Derivatives, That Occurs upon Changing the Medium of Cells in Culture |
Q41079756 | Differential effects of sphingomyelinase and cell-permeable ceramide analogs on proliferation of Swiss 3T3 fibroblasts |
Q71907697 | Differential effects of synthetic sphingosine derivatives on melanoma cell motility, growth, adhesion and invasion in vitro |
Q28138229 | Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5 |
Q37830235 | Dissecting the role of the S1P/S1PR axis in health and disease. |
Q77780124 | Diversity and complexity of ceramide signalling in apoptosis |
Q36256204 | Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival |
Q34389208 | Effect of acidic phospholipids on sphingosine kinase |
Q41991229 | Effect of sphingosine derivatives on calcium fluxes in thyroid FRTL-5 cells |
Q41533197 | Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx |
Q30439954 | Engineering vascularized tissues using natural and synthetic small molecules |
Q40646901 | Enhanced Serine Palmitoyltransferase Expression in Proliferating Fibroblasts, Transformed Cell Lines, and Human Tumors |
Q36118256 | Entry of muscle satellite cells into the cell cycle requires sphingolipid signaling. |
Q40843502 | Enzymatic method for measurement of sphingosine 1-phosphate |
Q41015800 | Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins |
Q37408557 | Export and functions of sphingosine-1-phosphate. |
Q27009557 | Export of sphingosine-1-phosphate and cancer progression |
Q41832728 | Extracellular sphingosine 1-phosphate stimulates formation of ethanolamine from phosphatidylethanolamine: modulation of sphingosine 1-phosphate-induced mitogenesis by ethanolamine |
Q74044934 | F-12509A, a new sphingosine kinase inhibitor, produced by a discomycete |
Q36052555 | FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism |
Q91964712 | Fingolimod Plays Role in Attenuation of Myocardial Injury Related to Experimental Model of Cardiac Arrest and Extracorporeal Life Support Resuscitation |
Q55285115 | First evidence of SGPL1 expression in the cell membrane silencing the extracellular S1P siren in mammary epithelial cells. |
Q49014246 | Functional expression and signaling properties of cloned human parathyroid hormone receptor in Xenopus oocytes. Evidence for a novel signaling pathway |
Q31640177 | Functions of a new family of sphingosine-1-phosphate receptors |
Q47174627 | G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts |
Q35824021 | Ganglioside/glycosphingolipid turnover: new concepts |
Q42205646 | Gelsolin and functionally similar actin-binding proteins are regulated by lysophosphatidic acid |
Q34361286 | Glial cell responses to lipids bound to albumin in serum and plasma |
Q33808022 | Growth-limiting role of endothelial cells in endoderm development |
Q39392240 | H-Ras increases release of sphingosine resulting in down-regulation of TSP-1 in non-transformed cells. |
Q41871959 | Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells |
Q90655362 | Human Remyelination Promoting Antibody Stimulates Astrocytes Proliferation Through Modulation of the Sphingolipid Rheostat in Primary Rat Mixed Glial Cultures |
Q40471900 | Human placental lipid induces melanogenesis by increasing the expression of tyrosinase and its related proteins in vitro. |
Q44044901 | Human placental lipid induces mitogenesis and melanogenesis in B16F10 melanoma cells |
Q22254319 | Human sphingosine kinase: molecular cloning, functional characterization and tissue distribution |
Q42066158 | Identification and subcellular localization of sphinganine-phosphatases in rat liver |
Q24316056 | Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids |
Q73487746 | Identification of lysophospholipid receptors in human platelets: the relation of two agonists, lysophosphatidic acid and sphingosine 1-phosphate |
Q36898368 | Implication of sphingosin-1-phosphate in cardiovascular regulation |
Q39396610 | Induction of Ca2+ oscillations by selective, U73122-mediated, depletion of inositol-trisphosphate-sensitive Ca2+ stores in rabbit pancreatic acinar cells. |
Q64038867 | Influence of lipid diets on the number of metastases and ganglioside content of H59 variant tumors |
Q40870274 | Inhibition of chemotactic motility and trans-endothelial migration of human neutrophils by sphingosine 1-phosphate |
Q41272671 | Interaction of Ceramides, Sphingosine, and Sphingosine 1-Phosphate in Regulating DNA Synthesis and Phospholipase D Activity |
Q45919951 | Intracellular IL-15 controls mast cell survival. |
Q28743138 | Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase |
Q42806506 | Involvement of sphingolipids metabolites in cellular proliferation modulated by ganglioside GM1. |
Q33808769 | Isoflurane protects human kidney proximal tubule cells against necrosis via sphingosine kinase and sphingosine-1-phosphate generation |
Q45177699 | Janus kinase 3: a novel target for selective transplant immunosupression |
Q24657671 | Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1 |
Q64098656 | Links between accelerated replicative cellular senescence and down-regulation of SPHK1 transcription |
Q36282427 | Lipidomic approach for stratification of acute myeloid leukemia patients |
Q30424618 | Local delivery of FTY720 accelerates cranial allograft incorporation and bone formation |
Q47233200 | Lysophosphatidic Acid Signaling Axis Mediates Ceramide 1-Phosphate-Induced Proliferation of C2C12 Myoblasts |
Q42540355 | Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist |
Q42131433 | Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis. |
Q37173208 | Lysophospholipid receptors in vertebrate development, physiology, and pathology |
Q93370188 | Metabolic pathways modulate the neuronal toxicity associated with fragile X-associated tremor/ataxia syndrome |
Q57364601 | Metabolism and physiological functions of sphingolipids |
Q34747143 | Mitochondria and ceramide: intertwined roles in regulation of apoptosis |
Q41728046 | Modulation of cell signalling by ceramides. |
Q37707542 | Molecular cloning and characterization of SCaMPER, a sphingolipid Ca2+ release-mediating protein from endoplasmic reticulum |
Q77998315 | N-acetyl-sphingenine-1-phosphate is a potent calcium mobilizing agent |
Q36881675 | New insights into glycosphingolipid functions--storage, lipid rafts, and translocators |
Q72134308 | On the presence of phosphorylated sphingoid bases in rat tissues. A mass-spectrometric approach |
Q37070994 | PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation |
Q41093160 | Pertussis toxin- and PMA-insensitive calcium mobilization by sphingosine in CFPAC-1 cells: evidence for a phosphatidic acid-dependent mechanism |
Q30410634 | Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors |
Q58691421 | Phospholipid and Lipid Derivatives as Potential Neuroprotective Compounds |
Q42826788 | Phosphorylated cis-4-methylsphingosine mimics the mitogenic effect of sphingosine-1-phosphate in Swiss 3T3 fibroblasts |
Q33930354 | Physiology and pathophysiology of sphingolipid metabolism and signaling |
Q35146936 | Pleiotropic actions of sphingosine-1-phosphate |
Q42467452 | Predominance of the acylation route in the metabolic processing of exogenous sphingosine in neural and extraneural cells in culture |
Q74182787 | Prenatal alcohol exposure increases TNFalpha-induced cytotoxicity in primary astrocytes |
Q36727326 | Protein kinase C-epsilon regulates sphingosine 1-phosphate-mediated migration of human lung endothelial cells through activation of phospholipase D2, protein kinase C-zeta, and Rac1. |
Q34559806 | Regulating survival and development in the retina: key roles for simple sphingolipids |
Q36715339 | Regulation and functional roles of sphingosine kinases |
Q48128990 | Regulation of mitogen-activated protein kinases by sphingolipid products in oligodendrocytes. |
Q40890957 | Regulation of proliferation and apoptosis by Ras and Rho GTPases through specific phospholipid-dependent signaling |
Q37415111 | Regulation of vascular physiology and pathology by the S1P2 receptor subtype. |
Q38358894 | Regulatory role of ceramide in interleukin (IL)-1 beta-induced E-selectin expression in human umbilical vein endothelial cells. Ceramide enhances IL-1 beta action, but is not sufficient for E-selectin expression |
Q36553395 | Reminiscence of our research on membrane phospholipids in mammalian cells by using the novel technology |
Q30464665 | Responses to sphingosine-1-phosphate in X. laevis oocytes: similarities with lysophosphatidic acid signaling |
Q26996672 | Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy |
Q51606648 | Rheumatology mini focus. |
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Q34017124 | Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro. |
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Q34879183 | Roles of sphingosine 1-phosphate on tumorigenesis |
Q37699303 | Roles of sphingosine-1-phosphate in reproduction |
Q39169246 | Runx1 Orchestrates Sphingolipid Metabolism and Glucocorticoid Resistance in Lymphomagenesis. |
Q33886533 | S1P metabolism in cancer and other pathological conditions |
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Q36843303 | Sphingolipid profile alters in retinal dystrophic P23H-1 rats and systemic FTY720 can delay retinal degeneration |
Q35675184 | Sphingolipid signaling and hematopoietic malignancies: to the rheostat and beyond |
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Q43559665 | Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells |
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Q36890026 | Sphingosine 1-phosphate potentiates human lung fibroblast chemotaxis through the S1P2 receptor |
Q79291156 | Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis: Role of intracellular calcium and nitric oxide |
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Q34126142 | Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors |
Q41122787 | Sphingosine 1-phosphate stimulates Na+/H+ exchange in thyroid FRTL-5 cells |
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Q34128454 | Sphingosine 1-phosphate, a key cell signaling molecule |
Q37249572 | Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness |
Q22011004 | Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5 |
Q28297208 | Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218 |
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Q36294755 | Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. |
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Q36235805 | Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction |
Q44371529 | Sphingosine-1-phosphate inhibits acid sphingomyelinase and blocks apoptosis in macrophages |
Q71034353 | Sphingosine-1-phosphate inhibits actin nucleation and pseudopodium formation to control cell motility of mouse melanoma cells |
Q38935993 | Sphingosine-1-phosphate inhibits differentiation of C3H10T1/2 cells into adipocyte |
Q44648524 | Sphingosine-1-phosphate inhibits human keratinocyte proliferation via Akt/protein kinase B inactivation |
Q54342529 | Sphingosine-1-phosphate mediates epidermal growth factor-induced muscle satellite cell activation. |
Q42444888 | Sphingosine-1-phosphate promotes mouse melanocyte survival via ERK and Akt activation |
Q41065014 | Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor |
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Q37317783 | Sphingosine-1-phosphate receptor-1 (S1P1) is expressed by lymphocytes, dendritic cells, and endothelium and modulated during inflammatory bowel disease |
Q42525224 | Sphingosine-1-phosphate stimulates human Caco-2 intestinal epithelial proliferation via p38 activation and activates ERK by an independent mechanism |
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Q41656256 | Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines |
Q35377676 | Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss |
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Q34264490 | Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator |
Q42556020 | Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate |
Q47982503 | Survival by Mac-1-mediated adherence and anoikis in phorbol ester-treated HL-60 cells |
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Q34255382 | Systemic distribution, subcellular localization and differential expression of sphingosine-1-phosphate receptors in benign and malignant human tissues |
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Q34364844 | Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond |
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Q36790267 | The apolipoprotein m-sphingosine-1-phosphate axis: biological relevance in lipoprotein metabolism, lipid disorders and atherosclerosis |
Q27657731 | The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen |
Q42982087 | The differential regulation of cyclic AMP by sphingomyelin-derived lipids and the modulation of sphingolipid-stimulated extracellular signal regulated kinase-2 in airway smooth muscle |
Q27935031 | The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses |
Q33918545 | The electrostatics of lipid surfaces |
Q45287768 | The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation |
Q30430805 | The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720. |
Q40963836 | The identification of myriocin-binding proteins |
Q38738515 | The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells |
Q37293864 | The influence of sphingosine-1-phosphate receptor signaling on lymphocyte trafficking: how a bioactive lipid mediator grew up from an "immature" vascular maturation factor to a "mature" mediator of lymphocyte behavior and function. |
Q34486205 | The interaction between C5a and sphingosine-1-phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation |
Q73212884 | The mycotoxin fumonisin B1 inhibits integrin-mediated cell-matrix adhesion |
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