| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Masayuki Nagahashi | Q87606415 |
| P2093 | author name string | Kazuaki Takabe | |
| Toshifumi Wakai | |||
| Kenji Sakimura | |||
| Manabu Abe | |||
| P2860 | cites work | Hallmarks of Cancer: The Next Generation | Q22252312 |
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| Resolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancer | Q26741524 | ||
| Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential | Q26766425 | ||
| Sphingosine-1-phosphate in chronic intestinal inflammation and cancer | Q26852824 | ||
| Export of sphingosine-1-phosphate and cancer progression | Q27009557 | ||
| Cancer-related inflammation | Q27860907 | ||
| Inflammation and cancer: back to Virchow? | Q28036756 | ||
| Conjugated bile acid-activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression | Q28250778 | ||
| Molecular mechanisms of cancer development in obesity | Q28253823 | ||
| Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis | Q28271008 | ||
| Sphingosine-1-phosphate lyase in immunity and cancer: silencing the siren | Q28297052 | ||
| The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice | Q28588851 | ||
| Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network | Q28591658 | ||
| Prevalence and trends in obesity among US adults, 1999-2008 | Q29547759 | ||
| Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1 | Q29619644 | ||
| Sphingosine-1-phosphate: an enigmatic signalling lipid | Q29620563 | ||
| Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory | Q30605352 | ||
| Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning | Q33615222 | ||
| Twofer anti-vascular therapy targeting sphingosine-1-phosphate for breast cancer. | Q33635116 | ||
| Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. | Q33773569 | ||
| Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2. | Q33796082 | ||
| Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation | Q33886596 | ||
| Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2. | Q34079007 | ||
| Sphingosine 1-phosphate and cancer | Q34121255 | ||
| The Sphingosine 1-Phosphate Transporter, SPNS2, Functions as a Transporter of the Phosphorylated Form of the Immunomodulating Agent FTY720 | Q34150336 | ||
| Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription. | Q34165938 | ||
| Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis. | Q34251293 | ||
| Sphingosine‐1‐phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration | Q34502695 | ||
| "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets | Q34593159 | ||
| The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors | Q34901297 | ||
| STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors. | Q34936215 | ||
| Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1 - Jekyll Hidden behind Hyde | Q35264010 | ||
| Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer. | Q35568516 | ||
| Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes | Q35631762 | ||
| Biologically active sphingolipids in cancer pathogenesis and treatment | Q35852313 | ||
| Inflammatory networks underlying colorectal cancer | Q35925068 | ||
| Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist | Q35978652 | ||
| The role of obesity in cancer survival and recurrence | Q36152955 | ||
| The role of sphingosine-1-phosphate in breast cancer tumor-induced lymphangiogenesis. | Q36241051 | ||
| Different Roles of Sphingosine Kinase 1 and 2 in Pancreatic Cancer Progression | Q93334151 | ||
| Shaping the landscape: metabolic regulation of S1P gradients | Q36356934 | ||
| Obesity and prognosis of breast cancer | Q36622232 | ||
| Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer. | Q36627430 | ||
| Plasma sphingosine 1-phosphate metabolism and analysis. | Q36991070 | ||
| Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods | Q37100281 | ||
| Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease | Q37259737 | ||
| Emerging Role of Sphingosine-1-phosphate in Inflammation, Cancer, and Lymphangiogenesis | Q37341131 | ||
| Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion. | Q37391105 | ||
| Sphingosine-1-phosphate in the lymphatic fluid determined by novel methods | Q37543777 | ||
| Inflammation and colon cancer | Q37737408 | ||
| Dissecting the role of the S1P/S1PR axis in health and disease. | Q37830235 | ||
| Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs | Q37965743 | ||
| Cancer-related inflammation: common themes and therapeutic opportunities | Q37972525 | ||
| Role of sphingosine 1-phosphate receptors, sphingosine kinases and sphingosine in cancer and inflammation | Q38597438 | ||
| DNA damage response and sphingolipid signaling in liver diseases | Q38619642 | ||
| Aspirin and colorectal cancer: the promise of precision chemoprevention. | Q38730064 | ||
| Targeting colorectal cancer cells by a novel sphingosine kinase 1 inhibitor PF-543. | Q38802701 | ||
| Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation and infection | Q38880225 | ||
| The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. | Q38909010 | ||
| Ceramidases, roles in sphingolipid metabolism and in health and disease | Q38988326 | ||
| TGFβ1 evokes myoblast apoptotic response via a novel signaling pathway involving S1P4 transactivation upstream of Rho-kinase-2 activation. | Q39115522 | ||
| Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1. | Q39383982 | ||
| The role of sphingosine in cell growth regulation and transmembrane signaling | Q40844224 | ||
| High levels of sphingolipids in human breast cancer. | Q40964594 | ||
| Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis | Q41089511 | ||
| Crystal Structure of Sphingosine Kinase 1 with PF-543 | Q41680076 | ||
| Sphingosine-1-phosphate transporters as targets for cancer therapy. | Q42181059 | ||
| The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish. | Q42551908 | ||
| Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens | Q42805681 | ||
| SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism | Q42810891 | ||
| Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients | Q46265539 | ||
| Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate | Q46494392 | ||
| Type 4 sphingosine 1-phosphate G protein-coupled receptor (S1P4) transduces S1P effects on T cell proliferation and cytokine secretion without signaling migration | Q46620860 | ||
| Targeting the SphK1/S1P/S1PR1 axis that links obesity, chronic inflammation and breast cancer metastasis. | Q47851281 | ||
| S1P Lyase Regulation of Thymic Egress and Oncogenic Inflammatory Signaling | Q48247517 | ||
| Expression of phosphorylated sphingosine kinase 1 is associated with diffuse type and lymphatic invasion in human gastric cancer | Q49686005 | ||
| Sphingolipid metabolism in cancer signalling and therapy | Q49950035 | ||
| Obesity, inflammation, and postmenopausal breast cancer: therapeutic implications. | Q51382532 | ||
| ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer. | Q52663621 | ||
| A Phase I Study of ABC294640, a First-in-Class Sphingosine Kinase-2 Inhibitor, in Patients with Advanced Solid Tumors. | Q55001442 | ||
| Ceramide species are elevated in human breast cancer and are associated with less aggressiveness. | Q55002300 | ||
| Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer | Q57024688 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial | Q6936496 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | neoplasm | Q1216998 |
| inflammation | Q101991 | ||
| P304 | page(s) | 3671-3678 | |
| P577 | publication date | 2018-10-15 | |
| 2018-12-01 | |||
| P1433 | published in | Cancer Science | Q326125 |
| P1476 | title | The role of sphingosine-1-phosphate in inflammation and cancer progression | |
| P478 | volume | 109 |
| Q90219783 | Lipid mediators of insulin signaling in diabetic kidney disease |
| Q91738678 | Roles of sphingosine-1-phosphate signaling in cancer |
| Q89552038 | Sphingosine-1-Phosphate in the Tumor Microenvironment: A Signaling Hub Regulating Cancer Hallmarks |
| Q101407729 | Therapeutic potential of Fingolimod in triple negative breast cancer preclinical models |
| Q92960121 | Triple-Negative Breast Cancer with High Levels of Annexin A1 Expression Is Associated with Mast Cell Infiltration, Inflammation, and Angiogenesis |
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