| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Elisa Giannoni | |
| Luigi Ippolito | |||
| Paola Chiarugi | |||
| Matteo Parri | |||
| P2860 | cites work | How do changes in the mtDNA and mitochondrial dysfunction influence cancer and cancer therapy? Challenges, opportunities and models | Q22252348 |
| The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 | Q24300456 | ||
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| Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase | Q28302589 | ||
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| Mitochondrial thioredoxin reductase regulates major cytotoxicity pathways of proteasome inhibitors in multiple myeloma cells. | Q33701777 | ||
| Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma | Q33798098 | ||
| Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer | Q33931343 | ||
| Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment | Q34099325 | ||
| Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation | Q34100946 | ||
| Vitamin C and survival among women with breast cancer: a meta-analysis | Q34409256 | ||
| Functional polarization of tumour-associated macrophages by tumour-derived lactic acid. | Q34429912 | ||
| Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198. | Q34493791 | ||
| ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis | Q34590025 | ||
| Serine catabolism regulates mitochondrial redox control during hypoxia | Q34644383 | ||
| The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. | Q34762767 | ||
| Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death | Q34771531 | ||
| Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines. | Q34893991 | ||
| Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells | Q35038005 | ||
| Interactions of mitochondrial thiols with nitric oxide | Q35184766 | ||
| Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function | Q35223050 | ||
| Metabolic state of glioma stem cells and nontumorigenic cells | Q35229102 | ||
| Phase 1, open-label, dose escalation, safety, and pharmacokinetics study of ME-344 as a single agent in patients with refractory solid tumors | Q35522903 | ||
| Enhanced NIR radiation-triggered hyperthermia by mitochondrial targeting | Q35557867 | ||
| Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism | Q35767081 | ||
| MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells. | Q35771944 | ||
| Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma | Q35899174 | ||
| Glucose oxidation modulates anoikis and tumor metastasis. | Q35943920 | ||
| Oxidative stress inhibits distant metastasis by human melanoma cells | Q36277720 | ||
| Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy | Q36416129 | ||
| Targeting antioxidants to mitochondria by conjugation to lipophilic cations. | Q36609730 | ||
| Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. | Q36639793 | ||
| Mitochondria: promising organelle targets for cancer diagnosis and treatment | Q91291136 | ||
| Stromal-induced mitochondrial re-education: Impact on epithelial-to-mesenchymal transition and cancer aggressiveness | Q92158952 | ||
| Cell Clustering Promotes a Metabolic Switch that Supports Metastatic Colonization | Q92854763 | ||
| Mitochondrial ROS Production Protects the Intestine from Inflammation through Functional M2 Macrophage Polarization. | Q50207597 | ||
| High vitamin D levels increase survival rates in patients with metastatic colorectal cancer. | Q53174683 | ||
| Signaling Pathways Regulating Redox Balance in Cancer Metabolism. | Q54979494 | ||
| Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells. | Q55031214 | ||
| Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth | Q57160050 | ||
| Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression | Q59799202 | ||
| PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers | Q60916001 | ||
| Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer | Q63884166 | ||
| Elevated level of mitochondrial reactive oxygen species via fatty acid β-oxidation in cancer stem cells promotes cancer metastasis by inducing epithelial-mesenchymal transition. | Q64923377 | ||
| Mitohormesis Primes Tumor Invasion and Metastasis. | Q64955421 | ||
| NRF2 and the Hallmarks of Cancer | Q88582817 | ||
| Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth | Q89565535 | ||
| Radiation-Induced Myofibroblasts Promote Tumor Growth via Mitochondrial ROS-Activated TGFβ Signaling | Q90451113 | ||
| Mitochondrial complex III is essential for suppressive function of regulatory T cells | Q90971059 | ||
| Mitochondrial miRNA Determines Chemoresistance by Reprogramming Metabolism and Regulating Mitochondrial Transcription | Q91116611 | ||
| Reductive carboxylation supports redox homeostasis during anchorage-independent growth | Q36883158 | ||
| The metabolic co-regulator PGC1α suppresses prostate cancer metastasis. | Q36944849 | ||
| IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism | Q36948088 | ||
| Does scavenging of mitochondrial superoxide attenuate cancer prosurvival signaling pathways? | Q36978013 | ||
| Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells | Q37059785 | ||
| Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II. | Q37158312 | ||
| Mitochondrial reactive oxygen species regulate hypoxic signaling | Q37603588 | ||
| Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity | Q37626226 | ||
| Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes | Q37653023 | ||
| Metformin increases PDH and suppresses HIF-1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma | Q37688194 | ||
| Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells | Q37723101 | ||
| Mitochondrial reactive oxygen species and cancer. | Q38351698 | ||
| Proteomic analysis of the vitamin C effect on the doxorubicin cytotoxicity in the MCF-7 breast cancer cell line. | Q38746649 | ||
| NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism. | Q38807020 | ||
| Hallmarks of cancer stem cell metabolism. | Q38842974 | ||
| Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread. | Q38852121 | ||
| A mitochondrial switch promotes tumor metastasis. | Q38971261 | ||
| Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration | Q39069327 | ||
| PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. | Q39193337 | ||
| The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction | Q39518049 | ||
| Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma | Q39621563 | ||
| A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis | Q39885131 | ||
| Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis. | Q40060668 | ||
| Metabolic shifts in residual breast cancer drive tumor recurrence | Q40201374 | ||
| Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. | Q40234453 | ||
| Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice. | Q40257551 | ||
| Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells. An in vitro comparative study | Q40394882 | ||
| Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression | Q41437712 | ||
| Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression | Q41522811 | ||
| Metabolic changes in cancer cells upon suppression of MYC. | Q42129085 | ||
| Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells by a non-apoptotic caspase-3 independent form of cell death | Q42458134 | ||
| Mitochondria as source of reactive oxygen species under oxidative stress. Study with novel mitochondria-targeted antioxidants--the "Skulachev-ion" derivatives | Q43109488 | ||
| PKC epsilon is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia | Q46263645 | ||
| Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor. | Q46272404 | ||
| MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation | Q46294767 | ||
| A Mitochondria-Targeted Cryptocyanine-Based Photothermogenic Photosensitizer. | Q46345602 | ||
| Oxidative stress in malignant melanoma enhances tumor necrosis factor-α secretion of tumor-associated macrophages that promote cancer cell invasion | Q46413110 | ||
| Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages | Q46485595 | ||
| The promise and perils of antioxidants for cancer patients | Q46868736 | ||
| Attenuation of CD4+CD25+ Regulatory T Cells in the Tumor Microenvironment by Metformin, a Type 2 Diabetes Drug | Q47126247 | ||
| Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer | Q47615969 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P304 | page(s) | 256 | |
| P577 | publication date | 2020-02-28 | |
| P1433 | published in | Frontiers in Oncology | Q26839986 |
| P1476 | title | Mitochondrial Redox Hubs as Promising Targets for Anticancer Therapy | |
| P478 | volume | 10 |
| Q100295054 | Mitochondrial DNA Haplotypes as Genetic Modifiers of Cancer | cites work | P2860 |
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