Interferon gamma in cancer immunotherapy

scientific article published on 23 July 2018

Interferon gamma in cancer immunotherapy is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1002/CAM4.1700
P932PMC publication ID6143921
P698PubMed publication ID30039553

P50authorJian LuQ81779949
Ling NiQ90435678
P2860cites workIFN-γ orchestrates tumor elimination, tumor dormancy, tumor escape, and progressionQ87848206
Interferon-gamma induces autophagy-associated apoptosis through induction of cPLA2-dependent mitochondrial ROS generation in colorectal cancer cellsQ88091546
Interferon Gamma Messenger RNA Signature in Tumor Biopsies Predicts Outcomes in Patients with Non-Small Cell Lung Carcinoma or Urothelial Cancer Treated with DurvalumabQ88537041
Myeloid-restricted ablation of Shp2 restrains melanoma growth by amplifying the reciprocal promotion of CXCL9 and IFN-γ production in tumor microenvironmentQ88796921
Interleukin 33 signaling restrains sporadic colon cancer in an interferon-gamma-dependent manner.Q49791560
Interferon-γ Signaling in Melanocytes and Melanoma Cells Regulates Expression of CTLA-4.Q49912481
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.Q50882019
Cellular teamwork in antibacterial innate immunity.Q50972079
Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity.Q50974735
IFN-γ-mediated inhibition of lung cancer correlates with PD-L1 expression and is regulated by PI3K-AKT signaling.Q52727974
Deficiency of interferon-gamma or its receptor promotes colorectal cancer development.Q54278902
PD-1 blockade augments Th1 and Th17 and suppresses Th2 responses in peripheral blood from patients with prostate and advanced melanoma cancerQ56898302
PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinationsQ28075712
The roles of IFN gamma in protection against tumor development and cancer immunoeditingQ28207895
Interferons, immunity and cancer immunoeditingQ28270336
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapyQ29619961
Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cellsQ33702231
MUC16 (CA125): tumor biomarker to cancer therapy, a work in progressQ33713506
IFN-γ regulates survival and function of tumor-induced CD11b+ Gr-1high myeloid derived suppressor cells by modulating the anti-apoptotic molecule Bcl2a1.Q34076238
The origins of cancer robustness and evolvability.Q34143477
VEGI-192, a new isoform of TNFSF15, specifically eliminates tumor vascular endothelial cells and suppresses tumor growthQ34439393
Comparison of the regulation of β-catenin signaling by type I, type II and type III interferons in hepatocellular carcinoma cellsQ34442738
RelA-Induced Interferon Response Negatively Regulates ProliferationQ35804406
Chimeric antigen receptor T cells shape myeloid cell function within the tumor microenvironment through IFN-γ and GM-CSF.Q36016640
Inflammatory mediators, tumor necrosis factor-α and interferon-γ, induce EMT in human PTC cell linesQ36085880
Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancerQ36260673
PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokinesQ36334073
Interferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cellsQ36521314
Interferon-gamma in the first-line therapy of ovarian cancer: a randomized phase III trialQ36621312
Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB.Q37046734
Anti-CTLA-4 therapy results in higher CD4+ICOShi T cell frequency and IFN-gamma levels in both nonmalignant and malignant prostate tissuesQ37115223
Downregulation of IFNG in CD4(+) T cells in lung cancer through hypermethylation: a possible mechanism of tumor-induced immunosuppressionQ37297734
Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer.Q37687020
IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor MicroenvironmentQ38699928
The untold story of IFN-γ in cancer biology.Q38922272
Interferon gamma induced by resveratrol analog, HS-1793, reverses the properties of tumor associated macrophagesQ38973749
Interferon-γ produced by tumor-infiltrating NK cells and CD4+ T cells downregulates TNFSF15 expression in vascular endothelial cellsQ39076405
Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunityQ39234961
IFN-γ mediates the antitumor effects of radiation therapy in a murine colon tumorQ41228057
Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.Q41493082
Interferon-γ-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expressionQ41590802
Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function.Q41954129
M2-polarised macrophages in infantile haemangiomas: correlation with promoted angiogenesisQ44492571
Toll-like receptor 2 ligand and interferon-γ suppress anti-tumor T cell responses by enhancing the immunosuppressive activity of monocytic myeloid-derived suppressor cellsQ47123300
Smac mimetics and type II interferon synergistically induce necroptosis in various cancer cell linesQ47783217
Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade.Q47799445
PD-L1 expression is mainly regulated by interferon gamma associated with JAK-STAT pathway in gastric cancer.Q48184221
Reversal of tumor acidosis by systemic buffering reactivates NK cells to express IFN-γ and induces NK cell-dependent lymphoma control without other immunotherapies.Q48240289
Interferon-γ and Colorectal Cancer: an up-to dateQ49199768
Interferon gamma, an important marker of response to immune checkpoint blockade in non-small cell lung cancer and melanoma patients.Q49501422
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue9
P921main subjectneoplasmQ1216998
immunotherapyQ1427096
immunologic factorQ50349184
P304page(s)4509-4516
P577publication date2018-07-23
2018-09-01
P1433published inCancer MedicineQ27724564
P1476titleInterferon gamma in cancer immunotherapy
P478volume7

Reverse relations

cites work (P2860)
Q100737000Baseline IFN-γ and IL-10 expression in PBMCs could predict response to PD-1 checkpoint inhibitors in advanced melanoma patients
Q98177744Clinical and Recent Patents Applications of PD-1/PD-L1 Targeting Immunotherapy in Cancer Treatment-Current Progress, Strategy, and Future Perspective
Q89576428Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma
Q92608513Existing and Emerging Biomarkers for Immune Checkpoint Immunotherapy in Solid Tumors
Q103756621IFNgamma-inducible CXCL10/CXCR3 axis alters the sensitivity of HEp-2 cells to ionizing radiation
Q99622572Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma
Q91711786NGS Evaluation of Colorectal Cancer Reveals Interferon Gamma Dependent Expression of Immune Checkpoint Genes and Identification of Novel IFNγ Induced Genes
Q64078881Novel predication of protein biomarkers in interferon-gamma-stimulated breast cancer cells
Q64117476PD-L1 upregulation in myeloma cells by panobinostat in combination with interferon-γ
Q98776112Searching for the real function of mTOR signaling in the regulation of PD-L1 expression
Q91898387Substantial remission of prostate adenocarcinoma with dendritic cell therapy APCEDEN® in combination with chemotherapy
Q97644684The Effects of Mesenchymal Stem Cells on Antimelanoma Immunity Depend on the Timing of Their Administration
Q96816703The interaction between ferroptosis and lipid metabolism in cancer
Q92669055Transcriptome meta-analysis reveals differences of immune profile between eutopic endometrium from stage I-II and III-IV endometriosis independently of hormonal milieu
Q101136383Using deep learning to predict anti-PD-1 response in melanoma and lung cancer patients from histopathology images

Search more.