Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade.

scientific article

Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M117.808121
P932PMC publication ID5682963
P698PubMed publication ID28912267

P50authorJacob ThompsonQ56837061
Dane K LarsenQ57125177
Margaret AlexanderQ57125216
Matthew WilliamsQ57424282
June L RoundQ87779262
Warren VothQ89444344
Marah C RuntschQ91619750
Thomas B HuffakerQ106584674
Andrew G RamsteadQ106585015
P2093author name stringRuozhen Hu
Ryan M O'Connell
Soh-Hyun Lee
William W Tang
Jared A Wallace
P2860cites workMicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell developmentQ24620604
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Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorderQ24649158
A viral microRNA functions as an orthologue of cellular miR-155Q24652947
MicroRNA-155 is induced during the macrophage inflammatory responseQ24683841
Nivolumab plus ipilimumab in advanced melanomaQ27852310
Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced CancerQ27860857
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
Immune checkpoint blockade: a common denominator approach to cancer therapyQ28083981
The widespread regulation of microRNA biogenesis, function and decayQ28131796
Combined Nivolumab and Ipilimumab or Monotherapy in Untreated MelanomaQ29615443
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumorsQ29619686
Nivolumab and ipilimumab versus ipilimumab in untreated melanomaQ29620657
MicroRNA-155 deficiency enhances the recruitment and functions of myeloid-derived suppressor cells in tumor microenvironment and promotes solid tumor growthQ34899627
miR-155 augments CD8+ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γc cytokines.Q34985536
MicroRNA-155 regulates inflammatory cytokine production in tumor-associated macrophages via targeting C/EBPbetaQ35011103
Host miR155 promotes tumor growth through a myeloid-derived suppressor cell-dependent mechanismQ35044328
Immune microenvironments in solid tumors: new targets for therapyQ35642044
miR-155 regulates IFN-γ production in natural killer cellsQ35885288
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompQ36375152
Interleukin-7 receptor expression: intelligent designQ36720948
miR-155-deficient bone marrow promotes tumor metastasisQ37107054
MicroRNA-155 confers encephalogenic potential to Th17 cells by promoting effector gene expressionQ37172065
MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancerQ37210788
Physiological and pathological roles for microRNAs in the immune systemQ37680666
IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasisQ38007051
miR-155: an ancient regulator of the immune systemQ38095500
Role of miR-155 in the regulation of lymphocyte immune function and disease.Q38168572
Tumor-associated macrophages: from mechanisms to therapyQ38230880
Tumor-associated macrophages as major players in the tumor microenvironmentQ38240110
Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targetingQ38320111
MicroRNAs as regulatory elements in immune system logicQ38819277
Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunityQ39234961
miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammationQ42631760
T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC.Q42687667
A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice.Q43787598
MicroRNA-155 and MicroRNA-21 promote the expansion of functional myeloid-derived suppressor cellsQ47035958
The earliest thymic progenitors for T cells possess myeloid lineage potential.Q50796225
Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.Q51014847
Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155Q84620188
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
P304page(s)18530-18541
P577publication date2017-09-14
P1433published inJournal of Biological ChemistryQ867727
P1476titleAntitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade
P478volume292

Reverse relations

cites work (P2860)
Q90166586Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients
Q58733261Effects of allergic stimulation and glucocorticoids on miR-155 in CD4 T-cells
Q89788065Inhibition of SHP-1 Expands the Repertoire of Antitumor T Cells Available to Respond to Immune Checkpoint Blockade
Q90435682Interferon gamma in cancer immunotherapy
Q55339993Key questions about the checkpoint blockade-are microRNAs an answer?
Q90389771LncRNA SNHG14/miR-5590-3p/ZEB1 positive feedback loop promoted diffuse large B cell lymphoma progression and immune evasion through regulating PD-1/PD-L1 checkpoint
Q64100323MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells
Q90609147MicroRNA (miR) dysregulation during Helicobacter pylori-induced gastric inflammation and cancer development: critical importance of miR-155
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Q90479399MicroRNAs as Immunotherapy Targets for Treating Gastroenterological Cancers
Q89836573Non-coding RNAs in CD8 T cell biology
Q89980594Noncoding RNAs in cancer immunity: functions, regulatory mechanisms, and clinical application
Q96609205Noncoding RNAs: the shot callers in tumor immune escape
Q60949868Oxymatrine and Cisplatin Synergistically Enhance Anti-tumor Immunity of CD8 T Cells in Non-small Cell Lung Cancer
Q90243992T Cell-Expressed microRNA-155 Reduces Lifespan in a Mouse Model of Age-Related Chronic Inflammation
Q89540099miR-155 Overexpression in OT-1 CD8+ T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen
Q58080415miR-155 expression in anti-tumor immunity: the higher the better?
Q98465623microRNAs Shape Myeloid Cell-Mediated Resistance to Cancer Immunotherapy

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