MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers

scholarly article by H Atakan Ekiz et al published 21 March 2019 in JCI insight

MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI.INSIGHT.126543
P932PMC publication ID6482995
P698PubMed publication ID30721153

P50authorThomas B HuffakerQ106584674
June L RoundQ87779262
P2093author name stringRyan M O'Connell
W Zac Stephens
Allie H Grossmann
Matthew A Williams
H Atakan Ekiz
P2860cites workGene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 proteinQ24641913
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorderQ24649158
CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation controlQ24676449
MicroRNA-155 is induced during the macrophage inflammatory responseQ24683841
MicroRNA gene expression deregulation in human breast cancerQ27860690
Regulation of microRNA biogenesisQ28243976
MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic diseaseQ28596130
limma powers differential expression analyses for RNA-sequencing and microarray studiesQ29617988
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TCGA Workflow: Analyze cancer genomics and epigenomics data using Bioconductor packagesQ31165459
MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 geneQ34107532
Regulation of the MIR155 host gene in physiological and pathological processesQ34318174
Genomic Classification of Cutaneous MelanomaQ34670776
miR-155 augments CD8+ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γc cytokines.Q34985536
Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancerQ35871752
Exosome-delivered microRNAs modulate the inflammatory response to endotoxinQ36018633
Tumor-induced myeloid-derived suppressor cell function is independent of IFN-γ and IL-4Rα.Q36905043
OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in CancerQ37059796
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seqQ37094024
Macrophage polarization in tumour progressionQ37158140
MicroRNA-155 confers encephalogenic potential to Th17 cells by promoting effector gene expressionQ37172065
Comprehensive analyses of tumor immunity: implications for cancer immunotherapyQ37193493
MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancerQ37210788
Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer.Q37586065
Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunityQ37734258
Control of immune response by amino acid metabolismQ37773432
Tumor-infiltrating lymphocytes and their significance in melanoma prognosisQ38164610
Identifying cell populations with scRNASeq.Q38676765
Revisit linear regression-based deconvolution methods for tumor gene expression dataQ38692499
MYC regulates the antitumor immune response through CD47 and PD-L1Q38787131
Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progressionQ39087629
MicroRNA-155 is a novel suppressor of ovarian cancer-initiating cells that targets CLDN1.Q39176725
Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunityQ39234961
Mechanisms and Dynamics of T Cell-Mediated Cytotoxicity In Vivo.Q39302905
microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasisQ39377895
MicroRNA-155 targets the SKI gene in human melanoma cell linesQ39564201
The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.Q41052928
Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers.Q42380545
miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammationQ42631760
A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice.Q43787598
Tumor promotion by intratumoral plasmacytoid dendritic cells is reversed by TLR7 ligand treatmentQ43881058
A description of the Molecular Signatures Database (MSigDB) Web siteQ46317320
Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade.Q47799445
IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients.Q47883923
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.Q52126962
Understanding the tumor immune microenvironment (TIME) for effective therapy.Q52311744
ImmPort, toward repurposing of open access immunological assay data for translational and clinical research.Q52683341
The Immune Landscape of Cancer.Q52720878
Quantifying tumor-infiltrating immune cells from transcriptomics data.Q52726457
Mutation load estimation model as a predictor of the response to cancer immunotherapy.Q55261882
Integrating single-cell transcriptomic data across different conditions, technologies, and speciesQ88243551
Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor MicroenvironmentQ89367617
The effect of cellular context on miR-155-mediated gene regulation in four major immune cell typesQ91495449
P4510describes a project that useslimmaQ112236343
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
Expression profilingQ60147249
single cell transcriptomicsQ105406038
P577publication date2019-03-21
P1433published inJCI insightQ27727187
P1476titleMicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers
P478volume4

Reverse relations

cites work (P2860)
Q90044590Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development
Q90243992T Cell-Expressed microRNA-155 Reduces Lifespan in a Mouse Model of Age-Related Chronic Inflammation
Q98465623microRNAs Shape Myeloid Cell-Mediated Resistance to Cancer Immunotherapy

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