review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1038/S41584-019-0307-6 |
P698 | PubMed publication ID | 31597952 |
P2093 | author name string | Nathalie C Lambert | |
P2860 | cites work | Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis | Q21144954 |
The DNA sequence of the human X chromosome | Q21735931 | ||
The Sequence of the Human Genome | Q22065842 | ||
X-inactivation profile reveals extensive variability in X-linked gene expression in females | Q22122481 | ||
Functional coherence of the human Y chromosome | Q24309552 | ||
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4 | Q24538382 | ||
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus | Q24630434 | ||
Global variation in copy number in the human genome | Q24658083 | ||
Risk for rheumatic disease in relation to ethnicity and admixture | Q24806807 | ||
eXclusion: toward integrating the X chromosome in genome-wide association analyses | Q36817316 | ||
Participation of women and sex analyses in late-phase clinical trials of new molecular entity drugs and biologics approved by the FDA in 2007-2009. | Q36991121 | ||
Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients | Q37052138 | ||
Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome | Q37083442 | ||
Dosage compensation and gene expression on the mammalian X chromosome: one plus one does not always equal two. | Q37085468 | ||
Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero | Q37111577 | ||
The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease | Q37138675 | ||
Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus | Q37159097 | ||
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation | Q37252315 | ||
Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases | Q37350872 | ||
CD40 and autoimmunity: the dark side of a great activator. | Q37365433 | ||
Microchimerism is strongly correlated with tolerance to noninherited maternal antigens in mice | Q37398315 | ||
Chimeric maternal cells with tissue-specific antigen expression and morphology are common in infant tissues | Q37439231 | ||
X-Linked miRNAs Associated with Gender Differences in Rheumatoid Arthritis. | Q37465525 | ||
Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases. | Q37536886 | ||
A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases | Q37621413 | ||
X chromosome inactivation: new players in the initiation of gene silencing | Q37730204 | ||
The X chromosome and immune associated genes | Q37969410 | ||
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells | Q27860714 | ||
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors | Q27860900 | ||
The influence of fetal loss on the presence of fetal cell microchimerism: a systematic review | Q28183659 | ||
Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope | Q28266117 | ||
Dosage compensation is less effective in birds than in mammals | Q28292598 | ||
Maternal-fetal immunology and autoimmune disease: is some autoimmune disease auto-alloimmune or allo-autoimmune? | Q28292677 | ||
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors | Q28303818 | ||
The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling | Q28306258 | ||
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis | Q28306666 | ||
Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: the Lyon repeat hypothesis | Q28776573 | ||
Genetics of rheumatoid arthritis contributes to biology and drug discovery | Q29417000 | ||
Non-coding RNAs in human disease | Q29618039 | ||
Gene action in the X-chromosome of the mouse (Mus musculus L.) | Q29618263 | ||
Estrogen modulation of endosome-associated toll-like receptor 8: an IFNα-independent mechanism of sex-bias in systemic lupus erythematosus. | Q30407671 | ||
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis | Q30419111 | ||
Detection of parent-of-origin effects for quantitative traits using general pedigree data. | Q30847614 | ||
Genomic environment predicts expression patterns on the human inactive X chromosome | Q33258823 | ||
Increased incidence of spontaneous abortion and infertility in women with scleroderma before disease onset: a controlled study | Q33560897 | ||
Adverse reproductive outcomes in women who subsequently develop rheumatoid arthritis | Q33561280 | ||
Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1. | Q33649753 | ||
Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome | Q33670694 | ||
Advances in lupus stemming from the parent-into-F1 model | Q33903169 | ||
A lesson in tolerance--maternal instruction to fetal cells | Q33915257 | ||
X-chromosome inactivation: counting, choice and initiation | Q33938436 | ||
Copy number variation in the human genome and its implication in autoimmunity | Q34016146 | ||
Chromosomal silencing and localization are mediated by different domains of Xist RNA. | Q34108304 | ||
The causes and consequences of random and non-random X chromosome inactivation in humans | Q34120150 | ||
Influence of MIF, CD40, and CD226 polymorphisms on risk of rheumatoid arthritis | Q34149621 | ||
Prenatal and postnatal prevalence of Klinefelter syndrome: a national registry study | Q34175866 | ||
The epidemiology of autoimmune diseases | Q34212462 | ||
Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis | Q34235185 | ||
Environmental risk factors in systemic sclerosis | Q34320718 | ||
Triple X syndrome: a review of the literature | Q34328701 | ||
Naturally acquired microchimerism: implications for transplantation outcome and novel methodologies for detection | Q34352679 | ||
A census of mammalian imprinting. | Q34430259 | ||
Sex differences and genomics in autoimmune diseases | Q37972053 | ||
Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: role of secretome and exosomes. | Q38107736 | ||
Graft-versus-host reactions: clues to the etiopathology of a spectrum of immunological diseases | Q38257691 | ||
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication | Q38313174 | ||
Genetic architectures of seropositive and seronegative rheumatic diseases | Q38439633 | ||
Association between FCGR3B copy number variations and susceptibility to autoimmune diseases: a meta-analysis | Q38592975 | ||
Maternal microchimerism in health and disease | Q38649974 | ||
Immunological implications of pregnancy-induced microchimerism. | Q38686693 | ||
Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases | Q38748557 | ||
Increased risk of rheumatoid arthritis among mothers with children who carry DRB1 risk-associated alleles | Q38846110 | ||
The genetics revolution in rheumatology: large scale genomic arrays and genetic mapping | Q39343367 | ||
Sex Differences in Pediatric Rheumatology. | Q40041622 | ||
Variant IL-1 receptor-associated kinase-1 mediates increased NF-kappa B activity | Q40085277 | ||
Rare X chromosome abnormalities in systemic lupus erythematosus and Sjögren's syndrome | Q40141505 | ||
Projections of US prevalence of arthritis and associated activity limitations | Q40361739 | ||
Expression of Long Interspersed Nuclear Element 1 Retroelements and Induction of Type I Interferon in Patients With Systemic Autoimmune Disease | Q40513722 | ||
Association between IRAK1 rs3027898 and miRNA-499 rs3746444 polymorphisms and rheumatoid arthritis : A case control study and meta-analysis | Q40599768 | ||
Association of TRAF1-C5 with risk of uveitis in juvenile idiopathic arthritis. | Q40670963 | ||
The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation | Q40690782 | ||
Allogeneic stem cell transplantation for rheumatic autoimmune diseases | Q42415511 | ||
Mosaic pattern of maternal and paternal keratinocyte clones in normal human epidermis revealed by analysis of X-chromosome inactivation | Q42506928 | ||
Landscape of X chromosome inactivation across human tissues | Q42696435 | ||
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy | Q42971266 | ||
Increased frequency of extremely skewed X chromosome inactivation in juvenile idiopathic arthritis | Q44388758 | ||
Association of pre-miRNA-146a rs2910164 and pre‑miRNA-499 rs3746444 polymorphisms and susceptibility to rheumatoid arthritis | Q44570330 | ||
Phenotypic differences in mosaic Klinefelter patients as compared with non-mosaic Klinefelter patients | Q46819221 | ||
Demethylation of CD40LG on the inactive X in T cells from women with lupus | Q46942094 | ||
Cytogenetics and fluorescence in situ hybridization assessment of sex-chromosome mosaicism in Klinefelter's syndrome | Q46975373 | ||
TLR7 escapes X chromosome inactivation in immune cells. | Q47548717 | ||
Sex, Symptom Severity, and Quality of Life in Rheumatology | Q47671088 | ||
Impaired reproductive fitness in mothers of children with juvenile autoimmune arthropathies | Q47857618 | ||
Dual effects of testosterone in Behcet's disease: implications for a role in disease pathogenesis | Q48034822 | ||
Corrected Estimates for the Prevalence of Self-Reported Doctor-Diagnosed Arthritis Among US Adults: Comment on the Article by Hootman et al. | Q48176398 | ||
X-chromosome-located microRNAs in immunity: might they explain male/female differences? The X chromosome-genomic context may affect X-located miRNAs and downstream signaling, thereby contributing to the enhanced immune response of females | Q49046928 | ||
Rheumatoid arthritis: Forward and reverse inheritance - the yin and the yang | Q49183897 | ||
Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis. | Q50095442 | ||
Mapping QTL affecting a systemic sclerosis-like disorder in a cross between UCD-200 and red jungle fowl chickens. | Q50506899 | ||
Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease. | Q50585017 | ||
X-Chromosome complement and estrogen receptor signaling independently contribute to the enhanced TLR7-mediated IFN-α production of plasmacytoid dendritic cells from women. | Q51105373 | ||
Female patients with ankylosing spondylitis: analysis of the impact of gender across treatment studies. | Q51286442 | ||
The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor α signaling. | Q51386967 | ||
Predicting response to anti-TNF treatment in rheumatoid arthritis patients. | Q51826669 | ||
Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance. | Q51973202 | ||
The Klinefelter syndrome is associated with high recurrence of copy number variations on the X chromosome with a potential role in the clinical phenotype. | Q53205705 | ||
Foxp3 expression in CD4+ T cells of patients with systemic lupus erythematosus: a comparative phenotypic analysis. | Q53531553 | ||
X chromosome monosomy: a common mechanism for autoimmune diseases. | Q53669531 | ||
Microchimerism and HLA-compatible relationships of pregnancy in scleroderma. | Q53782517 | ||
Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study | Q34431258 | ||
Cells from a vanished twin as a source of microchimerism 40 years later | Q34503687 | ||
Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients | Q34554770 | ||
Chromosome abnormalities found among 34,910 newborn children: results from a 13-year incidence study in Arhus, Denmark | Q34618515 | ||
Rheumatoid arthritis in a New England town. A prevalence study in Sudbury, Massachusetts | Q34703317 | ||
Ligation of TLR7 by rheumatoid arthritis synovial fluid single strand RNA induces transcription of TNFα in monocytes | Q34802780 | ||
Analysis of gender differences in genetic risk: association of TNFAIP3 polymorphism with male childhood-onset systemic lupus erythematosus in the Japanese population | Q34983538 | ||
A research study of the association between maternal microchimerism and systemic lupus erythematosus in adults: a comparison between patients and healthy controls based on single-nucleotide polymorphism using quantitative real-time PCR | Q34990102 | ||
Genetic susceptibility to systemic lupus erythematosus in the genomic era | Q35102487 | ||
Detection of parent-of-origin effects for quantitative traits in complete and incomplete nuclear families with multiple children | Q35198553 | ||
Acquisition of the rheumatoid arthritis HLA shared epitope through microchimerism | Q35282764 | ||
The global challenges and opportunities in the practice of rheumatology: white paper by the World Forum on Rheumatic and Musculoskeletal Diseases | Q35533763 | ||
Overexpression of transcripts containing LINE-1 in the synovia of patients with rheumatoid arthritis. | Q35552816 | ||
Association of the programmed cell death 1 (PDCD1) gene polymorphism with ankylosing spondylitis in the Korean population | Q35630023 | ||
Having older siblings is associated with gut microbiota development during early childhood | Q35732214 | ||
An overview of microRNAs | Q35858483 | ||
Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus | Q35884207 | ||
DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations | Q35896328 | ||
Increased incidence of pregnancy complications in women who later develop scleroderma: a case control study | Q35907714 | ||
Evaluation of X Chromosome Inactivation with Respect to HLA Genetic Susceptibility in Rheumatoid Arthritis and Systemic Sclerosis | Q36063970 | ||
Sex differences in the response to viral infections: TLR8 and TLR9 ligand stimulation induce higher IL10 production in males | Q36069263 | ||
Sex and gender differences in health. Science & Society Series on Sex and Science | Q36073394 | ||
Prospective assessment of fetal-maternal cell transfer in miscarriage and pregnancy termination | Q36152318 | ||
Mechanisms of X-chromosome inactivation | Q36251094 | ||
Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women | Q36302403 | ||
Skewing of X-inactivation ratios in blood cells of aging women is confirmed by independent methodologies | Q36510064 | ||
A female preponderance for chemically induced lupus in SJL/J mice | Q36536962 | ||
Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups | Q36595002 | ||
The rise, fall and subsequent triumph of thalidomide: lessons learned in drug development | Q36612613 | ||
A role for sex chromosome complement in the female bias in autoimmune disease | Q36639999 | ||
Overexpression of X-linked genes in T cells from women with lupus | Q36755936 | ||
Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse | Q36756652 | ||
Unusual maintenance of X chromosome inactivation predisposes female lymphocytes for increased expression from the inactive X | Q36802536 | ||
STAT4 polymorphism in a Chinese Han population with Vogt-Koyanagi-Harada syndrome and Behçet's disease. | Q54429851 | ||
Transfer of the shared epitope through microchimerism in women with rheumatoid arthritis. | Q54500832 | ||
Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. | Q54539944 | ||
Quantification of maternal microchimerism by HLA-specific real-time polymerase chain reaction: studies of healthy women and women with scleroderma. | Q54725774 | ||
Human adipose mesenchymal stem cells as potent anti-fibrosis therapy for systemic sclerosis. | Q54778469 | ||
Chimeric cells of maternal origin in juvenile idiopathic inflammatory myopathies | Q56001877 | ||
Female predisposition to TLR7-driven autoimmunity: gene dosage and the escape from X chromosome inactivation | Q57062603 | ||
Allogeneic hematopoietic stem cell transplantation for severe, refractory juvenile idiopathic arthritis | Q57094411 | ||
Evidence for an influence of chemokine ligand 3-like 1 (CCL3L1) gene copy number on susceptibility to rheumatoid arthritis | Q57154947 | ||
Two independent pathways of maternal cell transmission to offspring: through placenta during pregnancy and by breast-feeding after birth | Q57174534 | ||
Association of PDCD1 with susceptibility to systemic lupus erythematosus | Q57307140 | ||
Autoimmune diseases in women with Turner's Syndrome | Q57422870 | ||
Soluble HLA-G Expression Inversely Correlates With Fetal Microchimerism Levels in Peripheral Blood From Women With Scleroderma | Q57612657 | ||
Independent replication establishes the CD247 gene as a genetic systemic sclerosis susceptibility factor | Q57612950 | ||
PADI4 polymorphism predisposes male smokers to rheumatoid arthritis | Q58234815 | ||
The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis | Q58234902 | ||
Systemic lupus erythematosus and microchimerism in autoimmunity | Q60196112 | ||
Chromosomal abnormalities are related to location and grade of osteoarthritis | Q60203939 | ||
Maternal HLA class II compatibility in men with systemic lupus erythematosus | Q61283020 | ||
Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis | Q61651901 | ||
miRBase: from microRNA sequences to function | Q63649149 | ||
Altered X-chromosome inactivation in T cells may promote sex-biased autoimmune diseases | Q64076900 | ||
Regulating IRFs in IFN Driven Disease | Q64102243 | ||
Sonar evidence of early pregnancy failure in patients with twin conceptions | Q67555064 | ||
Rheumatoid arthritis in a Chippewa Band. I. Pilot screening study of disease prevalence | Q70786753 | ||
Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40 | Q72093299 | ||
HLA-DQA1*0501 is associated with diffuse systemic sclerosis in Caucasian men | Q73028022 | ||
Detection of maternofetal transfusion by placental alkaline phosphatase levels | Q73341631 | ||
Chimerism in children with juvenile dermatomyositis | Q73470675 | ||
Cutting edge: persistent fetal microchimerism in T lymphocytes is associated with HLA-DQA1*0501: implications in autoimmunity | Q73812144 | ||
FcgammaRIIA, FcgammaRIIIA and FcgammaRIIIB polymorphisms in Spanish patients with systemic lupus erythematosus | Q74470486 | ||
Microchimerism: incidental byproduct of pregnancy or active participant in human health? | Q77731243 | ||
The association between Turner's syndrome and juvenile rheumatoid arthritis | Q78166611 | ||
Myocardial-tissue-specific phenotype of maternal microchimerism in neonatal lupus congenital heart block | Q79313545 | ||
Mode of delivery - effects on gut microbiota and humoral immunity | Q79914166 | ||
Ankylosing spondylitis in a patient with Turner syndrome: a case report | Q80179220 | ||
Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells | Q80800895 | ||
Skewed X chromosome inactivation in blood cells of women with scleroderma | Q81726595 | ||
Rheumatic diseases and Klinefelter's syndrome | Q84071419 | ||
Skewed X chromosomal inactivation impacts T regulatory cell function in systemic sclerosis | Q84713390 | ||
The price of silence | Q84819921 | ||
A polymorphism in the 3’-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility | Q85092957 | ||
Age at symptom onset in ankylosing spondylitis: is there a gender difference? | Q87526642 | ||
Extensive cellular heterogeneity of X inactivation revealed by single-cell allele-specific expression in human fibroblasts | Q90226482 | ||
Fetal microchimerism by mode of delivery: a prospective cohort study | Q90917806 | ||
Mother-child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers | Q91011191 | ||
Although female patients with ankylosing spondylitis score worse on disease activity than male patients and improvement in disease activity is comparable, male patients show more radiographic progression during treatment with TNF-α inhibitors | Q91733334 | ||
Convergence in LINE-1 nucleotide variations can benefit redundantly forming triplexes with lncRNA in mammalian X-chromosome inactivation | Q92434468 | ||
P433 | issue | 11 | |
P921 | main subject | rheumatism | Q684924 |
gender bias | Q1501326 | ||
P304 | page(s) | 673-686 | |
P577 | publication date | 2019-10-09 | |
P1433 | published in | Nature Reviews Rheumatology | Q2107227 |
P1476 | title | Nonendocrine mechanisms of sex bias in rheumatic diseases | |
P478 | volume | 15 |
Q100428152 | Sex steroids and autoimmune rheumatic diseases: state of the art |
Q96304897 | The contribution of epigenetics to the pathogenesis and gender dimorphism of systemic sclerosis: a comprehensive overview |
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