Deficiency of HIF-1α enhances influenza A virus replication by promoting autophagy in alveolar type II epithelial cells

scientific article published on 01 December 2020

Deficiency of HIF-1α enhances influenza A virus replication by promoting autophagy in alveolar type II epithelial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1080/22221751.2020.1742585
P932PMC publication ID7144238
P698PubMed publication ID32208814

P50authorCaiqi ZhaoQ90625296
P2093author name stringJie Chen
Xiao Su
Yiyu Yang
Lianping Cheng
Kaifeng Xu
P2860cites workHIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensingQ24291102
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagyQ24312147
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxiaQ24315006
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1Q24320257
Human host factors required for influenza virus replicationQ24629972
Cancer-related inflammationQ27860907
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domainsQ28114920
A history of influenzaQ28189170
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1Q28506431
Methods in mammalian autophagy researchQ29547276
Autophagy as a regulated pathway of cellular degradationQ29547914
HIF-1alpha is essential for myeloid cell-mediated inflammationQ29617581
Control of influenza virus infection by immunity to conserved viral features.Q30343902
Antiviral agents active against influenza A viruses.Q30358429
Pandemic influenza: an inconvenient mutation.Q30375657
Three fatal cases of pandemic 2009 influenza A virus infection in Shenzhen are associated with cytokine storm.Q30396240
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressorsQ33261811
Surfactant proteins SP-B and SP-C and their precursors in bronchoalveolar lavages from children with acute and chronic inflammatory airway diseaseQ33327761
Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profilingQ33577373
The molecular mechanism of autophagyQ34520654
Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseasesQ34657382
Unraveling the mystery of swine influenza virusQ34986617
HIF transcription factors, inflammation, and immunityQ35137138
Cutting Edge: Critical Role of Glycolysis in Human Plasmacytoid Dendritic Cell Antiviral ResponsesQ36600894
Type 2 alveolar cells are stem cells in adult lung.Q36966911
A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infectionQ37148404
Influenza A Virus Entry: Implications in Virulence and Future TherapeuticsQ38077952
Role of HIF-1α and HIF-2α in osteoarthritisQ38305626
AMPK and autophagy in glucose/glycogen metabolismQ38571698
Nuclear translocation of HIF-1α induced by influenza A (H1N1) infection is critical to the production of proinflammatory cytokinesQ38768252
Local lung hypoxia determines epithelial fate decisions during alveolar regeneration.Q40122514
Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic InterventionQ40188145
Autophagy induction regulates influenza virus replication in a time-dependent mannerQ40218963
Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 CellsQ40410446
HIF-1alpha expression regulates the bactericidal capacity of phagocytesQ42876119
Autophagy is involved in influenza A virus replicationQ44330006
Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathwayQ44509761
BNIP3 mediates pre-myelinating oligodendrocyte cell death in hypoxia and ischemiaQ46946551
Into Thin Air: How We Sense and Respond to HypoxiaQ47658553
The evolution of epidemic influenzaQ53579716
Viral hijacking of cellular metabolismQ66679091
Deficiency of HIF-1α in myeloid cells protects Escherichia coli or LPS-induced acute lung injuryQ90282269
Autophagy Promotes Replication of Influenza A Virus In VitroQ90434138
Autophagy-related gene expression regulated by HIF-1α in salivary adenoid cystic carcinomaQ91474186
Antagonism between Antiviral Signaling and GlycolysisQ92212000
Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVSQ92470725
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectautophagyQ288322
influenza A virusQ834390
P304page(s)691-706
P577publication date2020-12-01
P1433published inEmerging Microbes & InfectionsQ27724513
P1476titleDeficiency of HIF-1α enhances influenza A virus replication by promoting autophagy in alveolar type II epithelial cells
P478volume9

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cites work (P2860)
Q97638090Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
Q99240951Hypoxia response and acute lung and kidney injury: possible implications for therapy of COVID-19

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