Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay

scientific article published on 01 February 2019

Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKY1260
P932PMC publication ID6379706
P698PubMed publication ID30566688

P2093author name stringEric E Swayze
Michael E Østergaard
Punit P Seth
Ruchi Gupta
Hans J Gaus
Alfred E Chappell
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P304page(s)1110-1122
P577publication date2019-02-01
P1433published inNucleic Acids ResearchQ135122
P1476titleCharacterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay
P478volume47

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cites work (P2860)
Q98386176Advances in oligonucleotide drug delivery
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Q92283429Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle
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Q90391306Mechanisms of palmitic acid-conjugated antisense oligonucleotide distribution in mice
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Q91604440Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins
Q92933262Understanding the effect of controlling phosphorothioate chirality in the DNA gap on the potency and safety of gapmer antisense oligonucleotides

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