review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Steven A Rosenzweig | Q61100598 |
P2860 | cites work | A single IGF1 allele is a major determinant of small size in dogs | Q24645092 |
Association of FOXO3A variation with human longevity confirmed in German centenarians | Q24646035 | ||
One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug | Q26747572 | ||
Imprinting disorders: a group of congenital disorders with overlapping patterns of molecular changes affecting imprinted loci | Q26995324 | ||
GSK-3β, a pivotal kinase in Alzheimer disease. | Q38218085 | ||
IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity | Q38247021 | ||
Insulin/IGF signaling and its regulation in Drosophila | Q38330262 | ||
Tau and neurodegenerative disease: the story so far. | Q38658752 | ||
Diabetes, Dementia and Hypoglycemia | Q38700492 | ||
Insulin Resistance and Neurodegeneration: Progress Towards the Development of New Therapeutics for Alzheimer's Disease | Q39042377 | ||
Molecular interaction between type 2 diabetes and Alzheimer's disease through cross-seeding of protein misfolding | Q39043775 | ||
Long-acting intranasal insulin detemir improves cognition for adults with mild cognitive impairment or early-stage Alzheimer's disease dementia | Q39102611 | ||
Closing in on a mechanism for activation | Q42136307 | ||
A brain circuit that synchronizes growth and maturation revealed through Dilp8 binding to Lgr3. | Q47071893 | ||
The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications. | Q47138434 | ||
Insulin-like Growth Factor 1 (IGF-1) as a marker of cognitive decline in normal ageing: A review. | Q47565092 | ||
Insulin Receptor Isoforms in Physiology and Disease: An Updated View | Q47668280 | ||
Intranasal insulin in Alzheimer's disease: Food for thought | Q47815013 | ||
Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums | Q47835103 | ||
Anti-Insulin-like Growth Factor Therapy in Breast Cancer. | Q49598271 | ||
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas | Q28217509 | ||
Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor | Q28611335 | ||
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice | Q29616382 | ||
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function | Q29618026 | ||
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes? | Q29619535 | ||
Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescence | Q30968725 | ||
Intranasal insulin enhances brain functional connectivity mediating the relationship between adiposity and subjective feeling of hunger | Q33686304 | ||
Insulin action in brain regulates systemic metabolism and brain function | Q33789365 | ||
Will targeting insulin growth factor help us or hurt us?: An oncologist's perspective | Q33926307 | ||
Alzheimer's disease is type 3 diabetes-evidence reviewed | Q34020000 | ||
Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study | Q34065827 | ||
Defining the pathway to insulin-like growth factor system targeting in cancer | Q34107722 | ||
The BATTLE trial: personalizing therapy for lung cancer | Q34275011 | ||
Insulin-like growth factors and neoplasia. | Q34330521 | ||
Teprotumumab for Thyroid-Associated Ophthalmopathy. | Q34556184 | ||
Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease. | Q35002762 | ||
Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice | Q35112453 | ||
Prediagnostic plasma IGFBP-1, IGF-1 and risk of prostate cancer | Q35178839 | ||
Insulin receptor substrate 2 is a negative regulator of memory formation | Q35211528 | ||
How IGF-1 activates its receptor | Q35240427 | ||
Insulin and the insulin receptor in experimental models of learning and memory. | Q35749624 | ||
Acquired resistance to drugs targeting receptor tyrosine kinases | Q35823437 | ||
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline | Q35858095 | ||
What's new in the IGF-binding proteins? | Q35874076 | ||
Molecular interactions of the IGF system | Q36152450 | ||
IGF1R levels in the brain negatively correlate with longevity in 16 rodent species. | Q36835828 | ||
The GSK3 hypothesis of Alzheimer's disease | Q37035378 | ||
Changes in insulin and insulin signaling in Alzheimer's disease: cause or consequence? | Q37179048 | ||
The cullin7 E3 ubiquitin ligase: a novel player in growth control | Q37300974 | ||
Risk of incident Alzheimer's disease in diabetic patients: a systematic review of prospective trials | Q37455807 | ||
The many faces of insulin-like peptide signalling in the brain | Q37994953 | ||
The role of neuronal insulin/insulin-like growth factor-1 signaling for the pathogenesis of Alzheimer's disease: possible therapeutic implications | Q38140979 | ||
Relationships of peripheral IGF-1, VEGF and BDNF levels to exercise-related changes in memory, hippocampal perfusion and volumes in older adults. | Q50550640 | ||
Insulin-like growth factor-1 predicts cognitive functions at 2-year follow-up in early, drug-naïve Parkinson's disease. | Q50750381 | ||
Depression and risk for onset of type II diabetes. A prospective population-based study. | Q50997140 | ||
How ligand binds to the type 1 insulin-like growth factor receptor. | Q52372488 | ||
Streptozotocin-Induced Diabetic Models in Mice and Rats. | Q53359503 | ||
Acquired Resistance to Drugs Targeting Tyrosine Kinases. | Q53701267 | ||
Streptozotocin Impairs Proliferation and Differentiation of Adult Hippocampal Neural Stem Cells in Vitro-Correlation With Alterations in the Expression of Proteins Associated With the Insulin System. | Q55254576 | ||
IGF-Binding Proteins: Why Do They Exist and Why Are There So Many? | Q55259134 | ||
Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling | Q57070244 | ||
Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones | Q58705586 | ||
Combined treatment with metformin and gefitinib overcomes primary resistance to EGFR-TKIs with EGFR mutation via targeting IGF-1R signaling pathway | Q58735770 | ||
Critical role of FOXO3a in carcinogenesis | Q60149868 | ||
Insulin Receptor Substrate Suppression by the Tyrphostin NT157 Inhibits Responses to Insulin-Like Growth Factor-I and Insulin in Breast Cancer Cells | Q62267699 | ||
Alzheimer's Disease and Cancer: When Two Monsters Cannot Be Together | Q64076827 | ||
Roles of Type 1 Insulin-Like Growth Factor (IGF) Receptor and IGF-II in Growth Regulation: Evidence From a Patient Carrying Both an 11p Paternal Duplication and 15q Deletion | Q64078621 | ||
The Role of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Nervous System | Q64104414 | ||
Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer's Disease Pathology and Shows Differential Expression in Transgenic Mice. | Q64899746 | ||
Three-dimensional co-culture of human monocytes and macrophages with tumor cells: analysis of macrophage differentiation and activation | Q71119389 | ||
Synthesis and characterization of insulin-like growth factor (IGF)-1 photoprobes selective for the IGF-binding proteins (IGFBPS). photoaffinity labeling of the IGF-binding domain on IGFBP-2 | Q73153548 | ||
Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects | Q81235261 | ||
40 YEARS of IGF1: IGF1: the Jekyll and Hyde of the aging brain | Q88608280 | ||
Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice | Q90559935 | ||
Structural basis of the activation of type 1 insulin-like growth factor receptor | Q90598146 | ||
Cross-Linking/Mass Spectrometry Uncovers Details of Insulin-Like Growth Factor Interaction With Insect Insulin Binding Protein Imp-L2 | Q90931091 | ||
Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior | Q91594974 | ||
Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model | Q91937435 | ||
Therapeutic Targeting of the IGF Axis | Q92642332 | ||
Multi-Loop Model of Alzheimer Disease: An Integrated Perspective on the Wnt/GSK3β, α-Synuclein, and Type 3 Diabetes Hypotheses | Q92649463 | ||
More Evidence of an Inverse Association Between Cancer and Alzheimer Disease | Q92934845 | ||
Rate of Memory Change Before and After Cancer Diagnosis | Q92934880 | ||
Cullin7 enhances resistance to trastuzumab therapy in Her2 positive breast cancer via degrading IRS-1 and downregulating IGFBP-3 to activate the PI3K/AKT pathway | Q92957757 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P577 | publication date | 2020-03-23 | |
P1433 | published in | F1000Research | Q27701587 |
P1476 | title | The Continuing Evolution of Insulin-like Growth Factor Signaling | |
P478 | volume | 9 |
Search more.