The antimicrobial peptide PFR induces necroptosis mediated by ER stress and elevated cytoplasmic calcium and mitochondrial ROS levels: cooperation with Ara-C to act against acute myeloid leukemia

scientific article published on 04 October 2019

The antimicrobial peptide PFR induces necroptosis mediated by ER stress and elevated cytoplasmic calcium and mitochondrial ROS levels: cooperation with Ara-C to act against acute myeloid leukemia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41392-019-0073-6
P932PMC publication ID6799817
P698PubMed publication ID31637016

P50authorCai Y FuQ80666635
Gang ShaoQ90783170
P2093author name stringLingfei Wang
Xi Wang
Tianxin Yang
Qiyu Zhang
Yuanting Jin
Feiyan Huang
Yudie Lv
Yueming Meng
P2860cites workEndoplasmic reticulum stress: cell life and death decisions.Q24536108
Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptidesQ35065154
APD3: the antimicrobial peptide database as a tool for research and educationQ36434966
PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cellsQ36565575
Ca(2+) homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signalingQ38496568
Regulation of necroptosis signaling and cell death by reactive oxygen speciesQ38751186
Effect of cytosine arabinoside metabolizing enzyme expression on drug toxicity in acute myeloid leukemiaQ47131526
The independence of and associations among apoptosis, autophagy, and necrosisQ89395265
Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overloadQ93132954
P921main subjectacute myeloid leukemiaQ264118
necroptosisQ3346925
P304page(s)38
P577publication date2019-10-04
P1476titleThe antimicrobial peptide PFR induces necroptosis mediated by ER stress and elevated cytoplasmic calcium and mitochondrial ROS levels: cooperation with Ara-C to act against acute myeloid leukemia
P478volume4

Reverse relations

Q104795183Nrf2 overexpression increases risk of high tumor mutation burden in acute myeloid leukemia by inhibiting MSH2cites workP2860

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