| P50 | author | Feng Shao | Q24836687 |
| | Pablo Pelegrín | Q55241090 |
| | Petr Broz | Q37378371 |
| P2860 | cites work | Nonsyndromic hearing impairment is associated with a mutation in DFNA5 | Q22003955 |
| | Structure, expression and chromosome mapping of MLZE, a novel gene which is preferentially expressed in metastatic melanoma cells | Q24290867 |
| | The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein | Q24300486 |
| | GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling | Q24304350 |
| | The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta | Q24305136 |
| | Active caspase-1 is a regulator of unconventional protein secretion | Q24308770 |
| | Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells | Q24523640 |
| | Caspase target drives pyroptosis | Q57937434 |
| | Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during infection | Q58091450 |
| | Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death | Q58563671 |
| | Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome | Q58606016 |
| | Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice | Q58617888 |
| | Delineating Immune-Mediated Mechanisms Underlying Hair Follicle Destruction in the Mouse Mutant Defolliculated | Q59384354 |
| | Gasdermin D Promotes AIM2 Inflammasome Activation and Is Required for Host Protection against Francisella novicida | Q59550079 |
| | Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion | Q60600312 |
| | Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection | Q60932493 |
| | Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation | Q64056422 |
| | The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes. | Q64881383 |
| | GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever. | Q64905464 |
| | Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture. | Q64984330 |
| | Polymorphisms in GSDMA and GSDMB are associated with asthma susceptibility, atopy and BHR | Q83453146 |
| | Microparticulate P2X7 and GSDM-D mediated regulation of functional IL-1β release | Q90470315 |
| | Gasdermin D plays a vital role in the generation of neutrophil extracellular traps | Q91132424 |
| | Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis | Q91132436 |
| | Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis | Q91253074 |
| | IRF2 transcriptionally induces GSDMD expression for pyroptosis | Q92198064 |
| | Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage | Q92766303 |
| | Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression | Q93199775 |
| | ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation | Q93358360 |
| | The clearance of dying cells: table for two | Q26753825 |
| | Inflammasome-dependent IL-1β release depends upon membrane permeabilisation | Q27331474 |
| | Pore-forming activity and structural autoinhibition of the gasdermin family | Q27709423 |
| | The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response | Q28242527 |
| | Structural basis of pore formation by the bacterial toxin pneumolysin | Q28246818 |
| | Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages | Q28250671 |
| | Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion | Q28270330 |
| | Non-canonical inflammasome activation targets caspase-11 | Q28506831 |
| | A new mutation Rim3 resembling Re(den) is mapped close to retinoic acid receptor alpha (Rara) gene on mouse chromosome 11 | Q28509564 |
| | Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner | Q28511298 |
| | Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores | Q28511994 |
| | Gasdermin (Gsdm) localizing to mouse Chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells | Q28585189 |
| | The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3 | Q28587608 |
| | Gsdma3 mutation causes bulge stem cell depletion and alopecia mediated by skin inflammation | Q28591264 |
| | Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous gland | Q28591374 |
| | Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy | Q28594398 |
| | Pro-inflammatory programmed cell death | Q29300293 |
| | CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin | Q30152651 |
| | GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death | Q30370004 |
| | Macrophages mediate flagellin induced inflammasome activation and host defense in zebrafish | Q30813096 |
| | Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium | Q34893093 |
| | The Association of GSDMB and ORMDL3 Gene Polymorphisms With Asthma: A Meta-Analysis | Q35123925 |
| | Gasdermin-B promotes invasion and metastasis in breast cancer cells | Q35133195 |
| | N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting | Q35770495 |
| | Gene Expression-Genotype Analysis Implicates GSDMA, GSDMB, and LRRC3C as Contributors to Inflammatory Bowel Disease Susceptibility | Q36119638 |
| | Membrane Repair: Mechanisms and Pathophysiology. | Q36146335 |
| | Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation | Q36190022 |
| | Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes | Q36266939 |
| | A p.C343S missense mutation in PJVK causes progressive hearing loss | Q36501157 |
| | Activation of human monocytes induces differential resistance to apoptosis with rapid down regulation of caspase-8/FLICE. | Q36733758 |
| | Expression of GSDML Associates with Tumor Progression in Uterine Cervix Cancer | Q36831403 |
| | The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles | Q36863973 |
| | Late-Onset Cryopyrin-Associated Periodic Syndromes Caused by Somatic NLRP3 Mosaicism-UK Single Center Experience | Q47129557 |
| | Ensembl 2018. | Q47151007 |
| | The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity | Q47251504 |
| | The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice | Q47258910 |
| | The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages. | Q47341459 |
| | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. | Q47843948 |
| | Social network architecture of human immune cells unveiled by quantitative proteomics | Q47967815 |
| | A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis. | Q50060224 |
| | Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes | Q50351560 |
| | Involvement of DFNB59 mutations in autosomal recessive nonsyndromic hearing impairment | Q50458450 |
| | Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages. | Q51065823 |
| | Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death. | Q51763136 |
| | Cryo-EM structure of the gasdermin A3 membrane pore. | Q52716591 |
| | A new Gsdma3 mutation affecting anagen phase of first hair cycle. | Q53546270 |
| | Gsdma3I359N is a novel ENU-induced mutant mouse line for studying the function of Gasdermin A3 in the hair follicle and epidermis | Q57315017 |
| | Mechanism of membrane pore formation by human gasdermin-D | Q57805428 |
| | GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes | Q37102414 |
| | Functional conservation of Gsdma cluster genes specifically duplicated in the mouse genome | Q37213439 |
| | Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. | Q37230975 |
| | Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. | Q37408201 |
| | An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells | Q37416793 |
| | Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics | Q37563863 |
| | Zebrafish tissue injury causes upregulation of interleukin-1 and caspase-dependent amplification of the inflammatory response | Q37566128 |
| | Gasdermin B expression predicts poor clinical outcome in HER2-positive breast cancer | Q37636623 |
| | Chromosome 17q21 Genes ORMDL3 and GSDMB in Asthma and Immune Diseases | Q38639458 |
| | Giant MACPF/CDC pore forming toxins: A class of their own. | Q38647638 |
| | AIM2 Engages Active but Unprocessed Caspase-1 to Induce Noncanonical Activation of the NLRP3 Inflammasome. | Q38659885 |
| | Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process | Q38746852 |
| | Human Monocytes Engage an Alternative Inflammasome Pathway | Q38781456 |
| | Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. | Q38835006 |
| | Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death | Q38835009 |
| | Inflammasomes: mechanism of assembly, regulation and signalling | Q38862650 |
| | P2X7 receptors mediate resistance to toxin-induced cell lysis | Q39028078 |
| | Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death | Q39033542 |
| | Programmed cell death as a defence against infection | Q39110327 |
| | Recent Insights into the Molecular Mechanisms Underlying Pyroptosis and Gasdermin Family Functions | Q39135386 |
| | Differential expression and localisation of gasdermin-like (GSDML), a novel member of the cancer-associated GSDMDC protein family, in neoplastic and non-neoplastic gastric, hepatic, and colon tissues | Q40044775 |
| | Brief Report: Late-Onset Cryopyrin-Associated Periodic Syndrome Due to Myeloid-Restricted Somatic NLRP3 Mosaicism | Q40102364 |
| | Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan | Q40626889 |
| | Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins | Q40629931 |
| | Rapid secretion of interleukin-1beta by microvesicle shedding | Q40765816 |
| | Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux | Q41108579 |
| | Loss of conserved Gsdma3 self-regulation causes autophagy and cell death | Q41136425 |
| | Shigella flexneri induces apoptosis in infected macrophages | Q41614246 |
| | Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides. | Q41836654 |
| | Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein. | Q42112444 |
| | The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge | Q42205331 |
| | The splicing mutant of the human tumor suppressor protein DFNA5 induces programmed cell death when expressed in the yeast Saccharomyces cerevisiae | Q42249031 |
| | The first cytokine sequence within cartilaginous fish: IL-1 beta in the small spotted catshark (Scyliorhinus canicula). | Q42672676 |
| | Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development | Q42689576 |
| | The Genotype-Tissue Expression (GTEx) Project | Q43115454 |
| | The deafness gene dfna5 is crucial for ugdh expression and HA production in the developing ear in zebrafish. | Q44737163 |
| | Ensembl Genomes 2018: an integrated omics infrastructure for non-vertebrate species. | Q46270713 |
| | Distribution of pejvakin in human spiral ganglion: An immunohistochemical study | Q46512012 |
| | Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. | Q47035972 |
| P433 | issue | 3 | |
| P921 | main subject | cell death | Q2383867 |
| P304 | page(s) | 143-157 | |
| P577 | publication date | 2019-11-05 | |
| P1433 | published in | Nature Reviews Immunology | Q43355 |
| P1476 | title | The gasdermins, a protein family executing cell death and inflammation | |
| P478 | volume | 20 | |