Probing key elements of teixobactin-lipid II interactions in membranes

scientific article published on 20 July 2018

Probing key elements of teixobactin-lipid II interactions in membranes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1039/C8SC02616E
P932PMC publication ID6124899
P698PubMed publication ID30210775

P50authorPo-Chao WenQ58140638
Susan B. RempeQ88213004
Emad TajkhorshidQ28052921
P2093author name stringJuan M Vanegas
P2860cites workSynthesis and structure-activity relationship of teixobactin analogues via convergent Ser ligationQ61779084
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Design and syntheses of highly potent teixobactin analogues against Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE) in vitro and in vivoQ49030931
Efficient total syntheses and biological activities of two teixobactin analoguesQ49064838
Synthesis and antibacterial studies of teixobactin analogues with non-isostere substitution of enduracididineQ49341522
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Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of l-allo-enduracididine with its isosteres.Q50560970
Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding.Q52641511
Multiple attack on bacteria by the new antibiotic teixobactin.Q52866776
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Rational design and synthesis of modified teixobactin analogues: in vitro antibacterial activity against Staphylococcus aureus, Propionibacterium acnes and Pseudomonas aeruginosa.Q54217425
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Bacterial lipid composition and the antimicrobial efficacy of cationic steroid compounds (Ceragenins).Q54438950
Wild-type Escherichia coli cells regulate the membrane lipid composition in a "window" between gel and non-lamellar structures.Q54591793
Re-evaluation of the N-terminal substitution and the D-residues of teixobactinQ57179926
Lysine Scanning of Arg-Teixobactin: Deciphering the Role of Hydrophobic and Hydrophilic ResiduesQ58034891
A new antibiotic kills pathogens without detectable resistanceQ24091299
Structural insight into the transglycosylation step of bacterial cell-wall biosynthesisQ27644008
Crystal structures of the complexes between vancomycin and cell-wall precursor analogsQ27652716
Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanismQ27678437
High-resolution crystal structure reveals molecular details of target recognition by bacitracinQ27679545
Targeting Antibiotic ResistanceQ28078130
MICs of mutacin B-Ny266, nisin A, vancomycin, and oxacillin against bacterial pathogensQ28343810
Update of the CHARMM all-atom additive force field for lipids: validation on six lipid typesQ29616710
Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activityQ31473388
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CHARMM additive all-atom force field for carbohydrate derivatives and its utility in polysaccharide and carbohydrate-protein modeling.Q34085563
The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibioticsQ34550741
At the membrane frontier: a prospectus on the remarkable evolutionary conservation of polyprenols and polyprenyl-phosphates.Q35661322
The antibiotic resistance crisis, with a focus on the United StatesQ36293305
Lipid II as a target for antibioticsQ36419233
Optimization of the additive CHARMM all-atom protein force field targeting improved sampling of the backbone φ, ψ and side-chain χ(1) and χ(2) dihedral anglesQ36546184
The penicillin-binding proteins: structure and role in peptidoglycan biosynthesisQ37081708
Elucidation of the Teixobactin PharmacophoreQ37616543
Lipid-linked oligosaccharides in membranes sample conformations that facilitate binding to oligosaccharyltransferaseQ38302930
Bacterial membrane lipids: diversity in structures and pathwaysQ38415713
Antibiotic innovation for future public health needsQ38666414
New Found Hope for Antibiotic Discovery: Lipid II InhibitorsQ38889355
Antimicrobial resistance in healthcare, agriculture and the environment: the biochemistry behind the headlinesQ39160453
Targeting a cell wall biosynthesis hot spotQ39413308
Dual Targeting of Cell Wall Precursors by Teixobactin Leads to Cell Lysis.Q40566928
Antibiotic effectiveness: balancing conservation against innovationQ41741779
New insights into the mode of action of the lantibiotic salivaricin B.Q41884008
Assembly and stability of nisin-lipid II poresQ45045783
X-ray crystallographic structure of a teixobactin analogue reveals key interactions of the teixobactin pharmacophore.Q46386811
Alanine scan reveals modifiable residues in teixobactinQ46549407
Investigation of the N-Terminus Amino Function of Arg10-TeixobactinQ46690045
Teixobactin as a scaffold for unlimited new antimicrobial peptides: SAR study.Q46745179
Binding Modes of Teixobactin to Lipid II: Molecular Dynamics StudyQ47267177
Converting Teixobactin into a Cationic Antimicrobial Peptide (AMP).Q47969690
Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activitiesQ48310474
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue34
P921main subjectteixobactinQ18720369
lipid IIQ21099571
P304page(s)6997-7008
P577publication date2018-07-20
P1433published inChemical ScienceQ2962267
P1476titleProbing key elements of teixobactin-lipid II interactions in membranes
P478volume9