Abstract is: Teixobactin (/ˌteɪksoʊˈbæktɪn/) is a peptide-like secondary metabolite of some species of bacteria, that kills some gram-positive bacteria. It appears to belong to a new class of antibiotics, and harms bacteria by binding to lipid II and , important precursor molecules for forming the cell wall. Teixobactin was discovered using a new method of culturing bacteria in soil, which allowed researchers to grow a previously unculturable bacterium now named Eleftheria terrae, which produces the antibiotic. Teixobactin was shown to kill Staphylococcus aureus and Mycobacterium tuberculosis.
type of chemical entity | Q113145171 |
peptide | Q172847 |
depsipeptide | Q413248 |
P1889 | different from | isomer of teixobactin | Q77517295 |
P703 | found in taxon | Eleftheria terrae | Q18759674 |
P2067 | mass | 1241.713207 | |
P3364 | stereoisomer of | isomer of teixobactin | Q77517295 |
P2868 | subject has role | antibiotic | Q12187 |
polypeptide antibiotic | Q3818190 |
Q24091299 | A new antibiotic kills pathogens without detectable resistance |
Q46549407 | Alanine scan reveals modifiable residues in teixobactin |
Q35595463 | Antibiotic discovery goes underground: The discovery of teixobactin could revitalise the search for new antibiotics based on the novel method the researchers used to identify the compound |
Q47267177 | Binding Modes of Teixobactin to Lipid II: Molecular Dynamics Study |
Q47609673 | Binding site and potency prediction of Teixobactin and other Lipid II ligands by statistical base scoring of conformational space maps. |
Q48221915 | Chemistry and Biology of Teixobactin |
Q47969690 | Converting Teixobactin into a Cationic Antimicrobial Peptide (AMP). |
Q90270711 | Dissecting the Binding Interactions of Teixobactin with the Bacterial Cell-Wall Precursor Lipid II |
Q40566928 | Dual Targeting of Cell Wall Precursors by Teixobactin Leads to Cell Lysis. |
Q37616543 | Elucidation of the Teixobactin Pharmacophore |
Q64062429 | Genomewide Profiling of the Enterococcus faecalis Transcriptional Response to Teixobactin Reveals CroRS as an Essential Regulator of Antimicrobial Tolerance |
Q92092107 | Gram-scale total synthesis of teixobactin promoting binding mode study and discovery of more potent antibiotics |
Q112938483 | Investigating Teixobactin Tolerance in Enterococcus faecalis |
Q112936990 | Investigating resistance in Enterococcus faecalis against the new antibiotic teixobactin |
Q87891234 | Lipopeptidomimetics derived from teixobactin have potent antibacterial activity against Staphylococcus aureus |
Q96171617 | Mode of action of teixobactins in cellular membranes |
Q52866776 | Multiple attack on bacteria by the new antibiotic teixobactin. |
Q91419607 | Probing key elements of teixobactin-lipid II interactions in membranes |
Q112932109 | Regulation of Antimicrobial Resistance in Enterococcus faecalis |
Q91025129 | Solution-phase total synthesis of teixobactin |
Q90972846 | Structural studies suggest aggregation as one of the modes of action for teixobactin |
Q91625649 | Synthesis and structure-activity relationships of teixobactin |
Q99708838 | Teixobactin Provides Protection against Inhalation Anthrax in the Rabbit Model |
Q38647719 | Teixobactin and Its Analogues: A New Hope in Antibiotic Discovery. |
Q46745179 | Teixobactin as a scaffold for unlimited new antimicrobial peptides: SAR study. |
Q113480788 | Teixobactin kills bacteria by a two-pronged attack on the cell envelope |
Q38531889 | Teixobactin, the first of a new class of antibiotics discovered by iChip technology? |
Q96291752 | Teixobactin: A Paving Stone towards A New Class of Antibiotics? |
Q93197947 | Teixobactin: a novel anti-infective agent |
Q40032243 | Teixobactin: a novel antibiotic in treatment of gram positive bacterial infections |
Q91595245 | Teixobactins: a new class of 21st century antibiotics to combat multidrug-resistant bacterial pathogens |
Q95839089 | The Killing Mechanism of Teixobactin against Methicillin-Resistant Staphylococcus aureus: an Untargeted Metabolomics Study |
Q92266971 | The Necessity of d-Thr in the New Antibiotic Teixobactin: A Molecular Dynamics Study |
Q53785473 | Total Synthesis of Teixobactin. |
Q42375863 | Total synthesis of teixobactin. |
Q46386811 | X-ray crystallographic structure of a teixobactin analogue reveals key interactions of the teixobactin pharmacophore. |
Q77517295 | isomer of teixobactin | different from | P1889 |
Q77517295 | isomer of teixobactin | stereoisomer of | P3364 |
Category:Teixobactin | wikimedia | |
Arabic (ar / Q13955) | تيكسوباكتين | wikipedia |
Теиксобактин | wikipedia | |
Catalan (ca / Q7026) | Teixobactina | wikipedia |
Teixobactin | wikipedia | |
Teixobactin | wikipedia | |
Teixobactin | wikipedia | |
Teixobactina | wikipedia | |
Persian (fa / Q9168) | تیکسوباکتین | wikipedia |
Teiksobaktiini | wikipedia | |
Teixobactine | wikipedia | |
hi | टीक्सोबैक्टीन | wikipedia |
Teixobaktin | wikipedia | |
Teixobactin | wikipedia | |
nb | Teixobactin | wikipedia |
Teixobactine | wikipedia | |
Tejksobaktyna | wikipedia | |
Teixobactina | wikipedia | |
Teixobactină | wikipedia | |
Теиксобактин | wikipedia | |
Теїксобактин | wikipedia | |
Teixobactin | wikipedia |
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