| human | Q5 |
| P496 | ORCID iD | 0000-0002-2122-9977 |
| P735 | given name | Michael | Q4927524 |
| Michael | Q4927524 | ||
| P106 | occupation | researcher | Q1650915 |
| P21 | sex or gender | male | Q6581097 |
| Q62835353 | A novel UGT1 marker associated with better tolerance against irinotecan-induced severe neutropenia in metastatic colorectal cancer patients |
| Q43248398 | A pharmacogenetics study of the human glucuronosyltransferase UGT1A4. |
| Q92708639 | Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability |
| Q51538549 | Age-related changes in the pharmacokinetic disposition of diazepam in foals. |
| Q37951689 | Anaesthesia and central nervous system disease in small animals. Part I: General considerations |
| Q37951690 | Anaesthesia and central nervous system disease in small animals. Part II: Anaesthetic management for specific diseases and procedures |
| Q38605451 | Anaesthesia for small animal patients with disease of the hepatic, renal or gastrointestinal system |
| Q51724201 | Anaesthesia for small animal patients with neuromuscular disease. |
| Q39524880 | Anaesthetic management of small animal patients with endocrine disease |
| Q38694663 | Anaesthetic management of the traumatized small animal patient |
| Q35650772 | Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases |
| Q73533620 | Biochemical basis for deficient paracetamol glucuronidation in cats: an interspecies comparison of enzyme constraint in liver microsomes |
| Q73253792 | Biotransformation of chlorzoxazone by hepatic microsomes from humans and ten other mammalian species |
| Q42698767 | Bisphenol-A glucuronidation in human liver and breast: identification of UDP-glucuronosyltransferases (UGTs) and influence of genetic polymorphisms |
| Q37184431 | CYP2B6 (c.516G→T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients |
| Q33918576 | CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants. |
| Q108275191 | CYP2B6(C.516G>T)and CYP2A6(*9B and *17) polymorphisms are independent preictors of efavirenz plasma concentrations in HIV -infected patients, |
| Q24606937 | CYP2B6, CYP2A6 and UGT2B7 genetic polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients |
| Q37422663 | Candidate gene polymorphisms in patients with acetaminophen-induced acute liver failure |
| Q93085021 | Canine Albumin Polymorphisms and Their Impact on Drug Plasma Protein Binding |
| Q98193051 | Canine orosomucoid (alpha-1 acid glycoprotein) variants and their influence on drug plasma protein binding |
| Q38083753 | Challenges in exploring the cytochrome P450 system as a source of variation in canine drug pharmacokinetics |
| Q46532736 | Comparative metabolism of mycophenolic acid by glucuronic acid and glucose conjugation in human, dog, and cat liver microsomes |
| Q52070687 | Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: ratios of accessory proteins as sources of discrepancies between the approaches. |
| Q46655056 | Comparison of chemotherapeutic drug resistance in cells transfected with canine ABCG2 or feline ABCG2. |
| Q24647242 | Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor |
| Q43514687 | Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes |
| Q51555719 | Development and validation of an ultrafast chromatographic method for quantification of the immunosuppressant mycophenolic acid in canine, feline and human plasma. |
| Q34702634 | Diabetes mellitus reduces activity of human UDP-glucuronosyltransferase 2B7 in liver and kidney leading to decreased formation of mycophenolic acid acyl-glucuronide metabolite |
| Q43129902 | Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10. |
| Q92091314 | Effect of First-Line Antituberculosis Therapy on Nevirapine Pharmacokinetics in Children Younger than Three Years Old |
| Q52742072 | Effect of Genetic Variation of NAT2 on Isoniazid and SLCO1B1 and CES2 on Rifampin Pharmacokinetics in Ghanaian Children with Tuberculosis. |
| Q36629228 | Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers |
| Q44666465 | Effect of age on in vitro triazolam biotransformation in male human liver microsomes |
| Q36729945 | Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers |
| Q44894927 | Effect of dietary soy on serum thyroid hormone concentrations in healthy adult cats |
| Q46972814 | Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: comparison with ritonavir |
| Q51674982 | Effect of midazolam infusion and flumazenil administration on epinephrine arrhythmogenicity in dogs anesthetized with halothane. |
| Q58609292 | Effect of rifampin/isoniazid-containing antituberculosis therapy on efavirenz pharmacokinetics in HIV-infected children aged 3 to 14 years old |
| Q37231835 | Effects of dietary soy isoflavones on health, steroidogenesis, and thyroid gland function in dogs |
| Q44160854 | Equine post-anesthetic lameness. A retrospective study |
| Q44550578 | Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism |
| Q44982091 | Evaluation of 5-hydroxytryptophol and other endogenous serotonin (5-hydroxytryptamine) analogs as substrates for UDP-glucuronosyltransferase 1A6. |
| Q37471079 | Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion |
| Q51389216 | Evidence for propofol hydroxylation by cytochrome P4502B11 in canine liver microsomes: breed and gender differences. |
| Q45415992 | Evidence for regulation of UDP-glucuronosyltransferase (UGT) 1A1 protein expression and activity via DNA methylation in healthy human livers |
| Q57172984 | Ex vivo binding of the immunosuppressant mycophenolic acid to dog and cat plasma proteins and the effect of co-incubated dexamethasone and prednisolone |
| Q37626582 | Factors associated with variability in rifampin plasma pharmacokinetics and the relationship between rifampin concentrations and induction of efavirenz clearance |
| Q48705097 | Factors influencing midazolam hydroxylation activity in human liver microsomes |
| Q36243643 | Favipiravir inhibits acetaminophen sulfate formation but minimally affects systemic pharmacokinetics of acetaminophen |
| Q51788360 | General anaesthesia for small animal patients with respiratory insufficiency. |
| Q61815001 | Genomes of Three Closely Related Caribbean Amazons Provide Insight for Species History and Conservation |
| Q46496009 | Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo |
| Q33714567 | Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases |
| Q24310887 | Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3 |
| Q28269219 | Human pregnane X receptor: genetic polymorphisms, alternative mRNA splice variants, and cytochrome P450 3A metabolic activity |
| Q28261566 | Identification and concentration of soy phytoestrogens in commercial dog foods |
| Q36354228 | Identification and validation of microRNAs directly regulating the UDP-glucuronosyltransferase 1A subfamily enzymes by a functional genomics approach |
| Q47724010 | Identification and validation of the microRNA response elements in the 3'-untranslated region of the UDP glucuronosyltransferase (UGT) 2B7 and 2B15 genes by a functional genomics approach. |
| Q90976192 | Identification of canine cytochrome P-450s (CYPs) metabolizing the tramadol (+)-M1 and (+)-M2 metabolites to the tramadol (+)-M5 metabolite in dog liver microsomes |
| Q45000626 | Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver. |
| Q37207247 | Identification of polymorphisms in the 3'-untranslated region of the human pregnane X receptor (PXR) gene associated with variability in cytochrome P450 3A (CYP3A) metabolism |
| Q37415778 | In vitro glucuronidation of fenofibric acid by human UDP-glucuronosyltransferases and liver microsomes. |
| Q51571189 | Influence of vaporizer setting on mask induction of dogs with isoflurane using an in-circuit vaporizer. |
| Q39836104 | Inhalation therapy. Oxygen administration, humidification, and aerosol therapy |
| Q72316122 | Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants |
| Q42931493 | Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase |
| Q43566974 | Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6. |
| Q43803829 | Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms. |
| Q24648578 | Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation |
| Q51770308 | Interstitial pH and pressure in the dependent biceps femoris muscle of laterally recumbent anesthetized horses. |
| Q69775804 | Investigation into the use of narcotic antagonists in the treatment of a stereotypic behavior pattern (crib-biting) in the horse |
| Q33798516 | Isoniazid mediates the CYP2B6*6 genotype-dependent interaction between efavirenz and antituberculosis drug therapy through mechanism-based inactivation of CYP2A6. |
| Q40534510 | Levothyroxine up-regulates P-glycoprotein independent of the pregnane X receptor |
| Q31011263 | Measurement of muscle surface capillary blood flow by laser Doppler flowmetry |
| Q45344293 | Mechanism of cytochrome P450-3A inhibition by ketoconazole |
| Q51422200 | Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms. |
| Q35065867 | Modest but variable effect of rifampin on steady-state plasma pharmacokinetics of efavirenz in healthy African-American and Caucasian volunteers |
| Q73394955 | Molecular basis for deficient acetaminophen glucuronidation in cats. An interspecies comparison of enzyme kinetics in liver microsomes |
| Q28138886 | Molecular genetic basis for deficient acetaminophen glucuronidation by cats: UGT1A6 is a pseudogene, and evidence for reduced diversity of expressed hepatic UGT1A isoforms |
| Q34638862 | Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10. |
| Q36951893 | Novel polymorphic human UDP-glucuronosyltransferase 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction |
| Q58113646 | Oral co-administration of fluconazole with tramadol markedly increases plasma and urine concentrations of tramadol and the O-desmethyltramadol metabolite (M1) in healthy dogs |
| Q44253445 | Paradoxically elevated efavirenz concentrations in HIV/tuberculosis- coinfected patients with CYP2B6 516TT genotype on rifampin-containing antituberculous therapy |
| Q91588228 | Personalized medicine: going to the dogs? |
| Q34313342 | Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes |
| Q92528050 | Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization |
| Q68107533 | Pharmacokinetics and milk residues of butorphanol in dairy cows after single intravenous administration |
| Q51678019 | Pharmacokinetics and preliminary observations of behavioral changes following administration of midazolam to dogs. |
| Q46309225 | Pharmacokinetics of a Sustained-release Formulation of Meloxicam After Subcutaneous Administration to Hispaniolan Amazon Parrots (Amazona ventralis). |
| Q69403368 | Pharmacokinetics of dantrolene sodium in horses |
| Q37186259 | Pharmacokinetics of efavirenz when co-administered with rifampin in TB/HIV co-infected patients: Pharmacogenetic effect of CYP2B6 variation |
| Q86199325 | Pharmacokinetics of meloxicam after intravenous, intramuscular, and oral administration of a single dose to Hispaniolan Amazon parrots (Amazona ventralis) |
| Q44961533 | Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats |
| Q47411407 | Polymorphisms in the canine glucocorticoid receptor alpha gene (NR3C1α). |
| Q87419978 | Pomegranate juice and pomegranate extract do not impair oral clearance of flurbiprofen in human volunteers: divergence from in vitro results |
| Q48618446 | Pomegranate juice does not impair clearance of oral or intravenous midazolam, a probe for cytochrome P450-3A activity: comparison with grapefruit juice |
| Q89149590 | Population variability in animal health: Influence on dose-exposure-response relationships: Part I: Drug metabolism and transporter systems |
| Q51769864 | Postanesthetic hind limb adductor myopathy in five horses. |
| Q51435651 | Propofol hydroxylation by dog liver microsomes: assay development and dog breed differences. |
| Q44419814 | Quantitation of CYP2B6, Constitutive Androstane Receptor, and Pregnane X Receptor mRNA levels |
| Q51850950 | Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues. |
| Q46140298 | Race, Gender, and Genetic Polymorphism Contribute to Variability in Acetaminophen Pharmacokinetics, Metabolism, and Protein-Adduct Concentrations in Healthy African-American and European-American Volunteers |
| Q39767875 | Recommended techniques in small animal anaesthesia. II. Intraoperative cardiac dysrhythmias and their treatment |
| Q39647553 | Recommended techniques in small animal anaesthesia. IV. Anaesthesia and cardiac disease |
| Q51839197 | Recommended techniques in small animal anaesthesia: an update. |
| Q38954155 | Relationship between the melanocortin-1 receptor (MC1R) variant R306ter and physiological responses to mechanical or thermal stimuli in Labrador Retriever dogs |
| Q83201640 | Ritonavir has minimal impact on the pharmacokinetic disposition of a single dose of bupropion administered to human volunteers |
| Q39733356 | Role for protein kinase C delta in the functional activity of human UGT1A6: implications for drug-drug interactions between PKC inhibitors and UGT1A6. |
| Q80057974 | Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice |
| Q37029122 | Role of NADPH-cytochrome P450 reductase and cytochrome-b5/NADH-b5 reductase in variability of CYP3A activity in human liver microsomes |
| Q46686015 | Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity |
| Q33909996 | Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes |
| Q44353598 | Serotonin (5-hydroxytryptamine) glucuronidation in vitro: assay development, human liver microsome activities and species differences |
| Q46109640 | Short-term clarithromycin administration impairs clearance and enhances pharmacodynamic effects of trazodone but not of zolpidem |
| Q35089862 | Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus |
| Q28208285 | Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9 |
| Q62836361 | THE NOVEL UGT1A9 INTRONIC I399 POLYMORPHISM APPEARS AS A PREDICTOR OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN GLUCURONIDATION LEVELS IN THE LIVER |
| Q36776594 | The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen- |
| Q51776737 | The clinical pharmacology of agents used to manage cardiovascular instability during general anaesthesia in small animals. |
| Q37427891 | Tramadol metabolism to O-desmethyl tramadol (M1) and N-desmethyl tramadol (M2) by dog liver microsomes: Species comparison and identification of responsible canine cytochrome P-450s (CYPs). |
| Q38751501 | Transcriptome association analysis identifies miR-375 as a major determinant of variable acetaminophen glucuronidation by human liver |
| Q46370914 | UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation |
| Q46370906 | UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: II. Functional impact of the three most common nonsynonymous UGT1A6 polymorphisms (S7A, T181A, and R184S). |
| Q28252818 | UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver |
| Q46573639 | UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver |
| Q46568226 | Udp-glucuronosyltransferase 2b7 is the major enzyme responsible for gemcabene glucuronidation in human liver microsomes |
| Q68488281 | Use of a narcotic antagonist (nalmefene) to suppress self-mutilative behavior in a stallion |
| Q67970663 | Use of narcotic antagonists to modify stereotypic self-licking, self-chewing, and scratching behavior in dogs |
| Q44251799 | Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6. |
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