scholarly article | Q13442814 |
P356 | DOI | 10.1002/GLIA.23634 |
P698 | PubMed publication ID | 31033014 |
P50 | author | Markus J Hofer | Q89305070 |
P2093 | author name string | Iain L Campbell | |
Barney Viengkhou | |||
Phillip K West | |||
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Lupus antibodies induce behavioral changes mediated by microglia and blocked by ACE inhibitors | Q91303656 | ||
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Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature. | Q37508060 | ||
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IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia | Q37615661 | ||
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Retracted article: Microglia-dependent synapse loss in type I interferon-mediated lupus | Q38725841 | ||
Microglial Interferon Signaling and White Matter. | Q38765964 | ||
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The role of interleukin-6 signaling in nervous tissue | Q38789542 | ||
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Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner | Q28267444 | ||
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature | Q28275605 | ||
Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy | Q28284465 | ||
Aicardi-Goutières syndrome: an update and results of interferon-alpha studies | Q28291222 | ||
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A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis | Q29615952 | ||
Fate mapping analysis reveals that adult microglia derive from primitive macrophages | Q29616177 | ||
Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome | Q30090228 | ||
Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse | Q30696856 | ||
Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology. | Q30805627 | ||
Colony-stimulating factor 1 receptor blockade prevents fractionated whole-brain irradiation-induced memory deficits | Q30805782 | ||
Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice | Q30843381 | ||
Clinical findings and adverse outcome in neonates with symptomatic congenital cytomegalovirus (SCCMV) infection | Q31048548 | ||
Glial contributions to neurodegeneration in tauopathies | Q32173558 | ||
Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis | Q33560182 | ||
Neurotoxic reactive astrocytes are induced by activated microglia | Q33602850 | ||
Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor. | Q33662701 | ||
Microglial depletion alters the brain neuroimmune response to acute binge ethanol withdrawal | Q33711718 | ||
A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica | Q33727402 | ||
Depletion of microglia exacerbates postischemic inflammation and brain injury | Q33727629 | ||
Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice | Q33730419 | ||
Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage | Q33828692 | ||
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Aicardi-Goutières syndrome is caused by IFIH1 mutations. | Q33858615 | ||
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IL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitis | Q34014515 | ||
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. | Q34123789 | ||
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Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells | Q48221138 | ||
Sall1 is a transcriptional regulator defining microglia identity and function. | Q48264747 | ||
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Inhibition of RGMa alleviates symptoms in a rat model of neuromyelitis optica. | Q48293438 | ||
Investigation Into the Effects of Tenilsetam on Markers of Neuroinflammation in GFAP-IL6 Mice. | Q48300482 | ||
Intracranial calcification with congenital rubella syndrome in a mother with serologic immunity. | Q48304304 | ||
Increased cerebrospinal fluid metalloproteinase-2 and interleukin-6 are associated with albumin quotient in neuromyelitis optica: Their possible role on blood-brain barrier disruption. | Q48493417 | ||
Site-specific production of IL-6 in the central nervous system retargets and enhances the inflammatory response in experimental autoimmune encephalomyelitis. | Q48524409 | ||
Microglia modulate wiring of the embryonic forebrain. | Q48583475 | ||
Neuroradiographic abnormalities in congenital cytomegalovirus infection. | Q48585880 | ||
Chronic complement C3 gene expression in the CNS of transgenic mice with astrocyte-targeted interleukin-6 expression. | Q48901153 | ||
Intrathecal synthesis of different alpha-interferons in patients with various neurological diseases. | Q49183237 | ||
A transcriptomic atlas of aged human microglia. | Q49578602 | ||
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy. | Q49789449 | ||
An open-label trial of JAK 1/2 blockade in progressive IFIH1-associated neuroinflammation. | Q50102108 | ||
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease. | Q50533712 | ||
Interleukin-6 analysis of 572 consecutive CSF samples from neurological disorders: A special focus on neuromyelitis optica. | Q51102172 | ||
CSF cytokine and chemokine profiles in acute disseminated encephalomyelitis. | Q51982590 | ||
Development of a Validated Interferon Score Using NanoString Technology. | Q52594390 | ||
In Utero Administration of Drugs Targeting Microglia Improves the Neurodevelopmental Outcome Following Cytomegalovirus Infection of the Rat Fetal Brain. | Q52645969 | ||
Immunohistochemistry using antibodies to alpha-interferon and its induced protein, MxA, in Alzheimer's and Parkinson's disease brain tissues. | Q53204231 | ||
Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6. | Q53778368 | ||
Targeting macrophage and microglia activation with colony stimulating factor 1 receptor inhibitor is an effective strategy to treat injury-triggered neuropathic pain. | Q53824229 | ||
Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1. | Q54295783 | ||
A potential role for interferon-alpha in the pathogenesis of HIV-associated dementia. | Q54713181 | ||
Depletion of microglia augments the dopaminergic neurotoxicity of MPTP. | Q55395566 | ||
Aquaporin-4 Autoantibodies From Neuromyelitis Optica Spectrum Disorder Patients Induce Complement-Independent Immunopathologies in Mice. | Q55498468 | ||
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies. | Q55548365 | ||
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Different responses to interferon beta-1b treatment in patients with neuromyelitis optica and multiple sclerosis | Q56771955 | ||
Markedly increased CSF interleukin-6 levels in neuromyelitis optica, but not in multiple sclerosis | Q56772014 | ||
Microglia in Alzheimer's disease | Q56922819 | ||
Type I interferonopathies: a novel set of inborn errors of immunity | Q56923635 | ||
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy | Q57265227 | ||
Effects of astrocyte-targeted production of interleukin-6 in the mouse on the host response to nerve injury | Q58027329 | ||
Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain | Q58027335 | ||
Enforced microglial depletion and repopulation as a promising strategy for the treatment of neurological disorders | Q58095253 | ||
Neuropsychiatric systemic lupus erythematosus | Q59924786 | ||
Analysis of IL-6/gp130 family receptor expression reveals that in contrast to astroglia, microglia lack the oncostatin M receptor and functional responses to oncostatin M | Q62658810 | ||
Activation of gp 130 by IL-6/soluble IL-6 receptor induces neuronal differentiation | Q62658913 | ||
Epigenetic regulation of brain region-specific microglia clearance activity. | Q64985968 | ||
Reactive gliosis as a consequence of interleukin-6 expression in the brain: studies in transgenic mice | Q71686282 | ||
Microglial localization of α-interferon receptor in human brain tissues | Q71874807 | ||
Expression of cytokine receptors in cultured neuronal and glial cells | Q72624819 | ||
Soluble interleukin 6 receptor in biological fluids from human origin | Q72775784 | ||
Intrathecal cytokines in systemic lupus erythematosus with central nervous system involvement | Q73086927 | ||
Development of extensive brain lesions following interferon beta therapy in relapsing neuromyelitis optica and longitudinally extensive myelitis | Q79838192 | ||
Cytokine-mediated inflammation, tumorigenesis, and disease-associated JAK/STAT/SOCS signaling circuits in the CNS | Q81683770 | ||
Does interferon beta treatment exacerbate neuromyelitis optica spectrum disorder? | Q83485788 | ||
Astrocyte-targeted production of interleukin-6 reduces astroglial and microglial activation in the cuprizone demyelination model: Implications for myelin clearance and oligodendrocyte maturation. | Q38809608 | ||
DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity | Q38908391 | ||
Microglia Priming with Aging and Stress | Q38948754 | ||
Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease | Q39059270 | ||
Intracellular Nucleic Acid Detection in Autoimmunity. | Q39112112 | ||
Type I interferon pathway in CNS homeostasis and neurological disorders. | Q39315038 | ||
Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases | Q39444706 | ||
IL-1β potently stabilizes IL-6 mRNA in human astrocytes | Q39596628 | ||
Predictors of clinical outcomes in patients with neuropsychiatric systemic lupus erythematosus. | Q40129046 | ||
Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice | Q40231922 | ||
Central inhibition of interleukin-6 trans-signaling during peripheral infection reduced neuroinflammation and sickness in aged mice | Q40282211 | ||
A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains | Q40371888 | ||
Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity. | Q40580578 | ||
Targeting the colony stimulating factor 1 receptor alleviates two forms of Charcot-Marie-Tooth disease in mice | Q40617443 | ||
Reexamination of the role of ubiquitin-like modifier ISG15 in the phenotype of UBP43-deficient mice | Q40701351 | ||
IL-6, IL-8, IP-10, MCP-1 and G-CSF are significantly increased in cerebrospinal fluid but not in sera of patients with central neuropsychiatric lupus erythematosus | Q40804722 | ||
Shared receptor components but distinct complexes for alpha and beta interferons | Q41008873 | ||
Interferon-alpha in lupus psychosis | Q41092098 | ||
Cytokines and matrix metalloproteinases in the cerebrospinal fluid of patients with acute transverse myelitis: an outcome analysis | Q41095945 | ||
The Lifespan and Turnover of Microglia in the Human Brain | Q41217922 | ||
Long-term Therapy With Interleukin 6 Receptor Blockade in Highly Active Neuromyelitis Optica Spectrum Disorder | Q41222751 | ||
Cytomegalovirus-induced brain malformations in fetuses | Q41930828 | ||
Interferon-α and the calcifying microangiopathy in Aicardi-Goutières syndrome. | Q42072565 | ||
Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution | Q42252166 | ||
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner. | Q42366438 | ||
Localization of metallothionein-I and -III expression in the CNS of transgenic mice with astrocyte-targeted expression of interleukin 6. | Q42462809 | ||
Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia | Q42512130 | ||
Regulation of microglial proliferation during chronic neurodegeneration | Q42713015 | ||
Interferon Beta treatment in neuromyelitis optica: increase in relapses and aquaporin 4 antibody titers | Q42942128 | ||
Cytomegalovirus induces interferon-stimulated gene expression and is attenuated by interferon in the developing brain. | Q42957459 | ||
Astrocytic damage is far more severe than demyelination in NMO: a clinical CSF biomarker study | Q42965338 | ||
Context-dependent IL-6 potentiation of interferon- gamma-induced IL-12 secretion and CD40 expression in murine microglia. | Q43284924 | ||
Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease | Q43736405 | ||
Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6. | Q43850180 | ||
Cytokines and other markers of intrathecal immune response in patients with herpes simplex encephalitis | Q44060297 | ||
Cerebrospinal fluid interleukin-6 and glial fibrillary acidic protein levels are increased during initial neuromyelitis optica attacks | Q44312623 | ||
Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease | Q44465591 | ||
Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-Goutières syndrome | Q44815605 | ||
Layer V cortical neurons require microglial support for survival during postnatal development. | Q45205743 | ||
A novel microglial subset plays a key role in myelinogenesis in developing brain | Q45248956 | ||
Prognostic value of cerebrospinal fluid cytokine changes in herpes simplex virus encephalitis | Q45386195 | ||
CD4+ and CD8+ cells accumulate in the brains of acquired immunodeficiency syndrome patients with human immunodeficiency virus encephalitis | Q45729143 | ||
TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. | Q45972218 | ||
A new fate mapping system reveals context-dependent random or clonal expansion of microglia | Q46046152 | ||
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy | Q46160288 | ||
Evolution of Neuropathologic Abnormalities Associated with Blood-Brain Barrier Breakdown in Transgenic Mice Expressing lnterleukin-6 in Astrocytes | Q46191027 | ||
Microglia and macrophages in brain homeostasis and disease | Q46461757 | ||
Age-related myelin degradation burdens the clearance function of microglia during aging. | Q46707647 | ||
Minimal role for STAT1 in interleukin-6 signaling and actions in the murine brain | Q46893501 | ||
The role of microglia and their CX3CR1 signaling in adult neurogenesis in the olfactory bulb | Q47141465 | ||
Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy | Q47175712 | ||
A progressive familial encephalopathy in infancy with calcifications of the basal ganglia and chronic cerebrospinal fluid lymphocytosis | Q34267120 | ||
Identification and validation of Ifit1 as an important innate immune bottleneck | Q34321053 | ||
Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation | Q34394932 | ||
Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. | Q34419957 | ||
Directing transition from innate to acquired immunity: defining a role for IL-6. | Q34449051 | ||
Brain MRI in patients with diffuse psychiatric/neuropsychological syndromes in systemic lupus erythematosus | Q34478835 | ||
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection | Q34548112 | ||
Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica. | Q34621516 | ||
Type I interferon receptors: biochemistry and biological functions. | Q34628239 | ||
Microglia regulate the number of neural precursor cells in the developing cerebral cortex | Q34649089 | ||
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. | Q34659689 | ||
Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus. | Q34671403 | ||
Characteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis | Q34700673 | ||
Neuromyelitis optica unique area postrema lesions: nausea, vomiting, and pathogenic implications | Q34743150 | ||
Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition | Q34878224 | ||
Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia | Q34918881 | ||
Microglia as a source and target of cytokines | Q34963658 | ||
Cerebrospinal fluid interleukin-6 in central nervous system inflammatory diseases | Q34981487 | ||
Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques | Q35030015 | ||
Inhibition of interleukin-6 trans-signaling in the brain facilitates recovery from lipopolysaccharide-induced sickness behavior | Q35040208 | ||
Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study. | Q35147055 | ||
Activation of neuronal NMDA receptors triggers transient ATP-mediated microglial process outgrowth. | Q35220649 | ||
Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. | Q35623089 | ||
Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis | Q35663520 | ||
Transverse Myelitis: pathogenesis, diagnosis and treatment | Q35672760 | ||
USP18 lack in microglia causes destructive interferonopathy of the mouse brain | Q35762623 | ||
Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice | Q35793406 | ||
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis. | Q35810427 | ||
Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology | Q35813745 | ||
Chronic IL-1β-mediated neuroinflammation mitigates amyloid pathology in a mouse model of Alzheimer's disease without inducing overt neurodegeneration | Q35827454 | ||
Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms | Q35870397 | ||
Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNalpha/beta and IL-1beta responses in the diseased brain and exacerbates chronic neurodegeneration | Q35906528 | ||
Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice | Q35908248 | ||
Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord | Q35962565 | ||
A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone | Q35995933 | ||
Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain | Q35998206 | ||
Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation. | Q36400800 | ||
Immunoinflammatory diseases of the central nervous system - the tale of two cytokines | Q36547012 | ||
Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6 | Q36631212 | ||
Principal components derived from CSF inflammatory profiles predict outcome in survivors after severe traumatic brain injury | Q36664950 | ||
Type I interferon response in the central nervous system | Q36780318 | ||
Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model | Q36799810 | ||
Neuropathology of early HIV-1 infection | Q36826608 | ||
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques | Q36863174 | ||
Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function | Q36907335 | ||
Interleukin-6 trans-signaling in the senescent mouse brain is involved in infection-related deficits in contextual fear conditioning. | Q36975857 | ||
Interleukin 6 plasma concentration associates with cognitive decline: the northern Manhattan study | Q37051184 | ||
Microglia ablation alleviates myelin-associated catatonic signs in mice | Q47281583 | ||
Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke. | Q47349753 | ||
Microglia are required for protection against lethal coronavirus encephalitis in mice | Q47548394 | ||
Expression profiling suggests microglial impairment in HIV neuropathogenesis. | Q47548985 | ||
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases | Q47568641 | ||
Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan | Q47642958 | ||
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models | Q47853785 | ||
Reduced cuprizone-induced cerebellar demyelination in mice with astrocyte-targeted production of IL-6 is associated with chronically activated, but less responsive microglia | Q47989996 | ||
Follicular Dendritic Cell Activation by TLR Ligands Promotes Autoreactive B Cell Responses. | Q47995140 | ||
Site-specific hippocampal pathophysiology due to cerebral overexpression of interleukin-6 in transgenic mice | Q48087469 | ||
Intrathecal synthesis of interferon-alpha in infants with progressive familial encephalopathy | Q48096912 | ||
Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging. | Q48137631 | ||
Neuromyelitis optica-like pathology is dependent on type I interferon response. | Q48151829 | ||
Expression of MRP14, 27E10, interferon-alpha and leukocyte common antigen by reactive microglia in postmortem human brain tissue | Q48164017 | ||
Cognitive impairment and cortical degeneration in neuromyelitis optica | Q48178165 | ||
P433 | issue | 10 | |
P921 | main subject | microglia | Q1622829 |
P304 | page(s) | 1821-1841 | |
P577 | publication date | 2019-04-29 | |
P1433 | published in | Glia | Q15716658 |
P1476 | title | Microglia responses to interleukin-6 and type I interferons in neuroinflammatory disease | |
P478 | volume | 67 |
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