Placental Galectins Are Key Players in Regulating the Maternal Adaptive Immune Response

scientific article published on 19 June 2019

Placental Galectins Are Key Players in Regulating the Maternal Adaptive Immune Response is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FIMMU.2019.01240
P932PMC publication ID6593412
P698PubMed publication ID31275299

P50authorAdi L TarcaQ88155056
Nandor Gabor ThanQ90970765
Petronella HupucziQ92812903
Sonia S HassanQ96619726
Hamutal MeiriQ114449283
Sinuhe HahnQ114449284
Kata JuhaszQ114449306
Roberto RomeroQ42734915
Katalin ParéjQ84829148
Andrea BaloghQ56257003
Offer ErezQ59705822
P2093author name stringZoltan Papp
Eva Pallinger
Peter Zavodszky
Simona W Rossi
Eszter Toth
Istvan Hajdu
Janos Matko
Arpad F Kovacs
Diana Csala
Nikolett L Szenasi
P2860cites workComparative analysis of decidual and peripheral immune cells and immune-checkpoint molecules during pregnancy in wild-type and PACAP-deficient miceQ90848759
Immune responses at the maternal-fetal interfaceQ91009830
Increased placental expression of Placental Protein 5 (PP5) / Tissue Factor Pathway Inhibitor-2 (TFPI-2) in women with preeclampsia and HELLP syndrome: Relevance to impaired trophoblast invasion?Q91900684
A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell deathQ24317162
Evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genesQ24629424
Galectins: guardians of eutherian pregnancy at the maternal-fetal interfaceQ26823092
Galectin-1 research in T cell immunity: Past, present and futureQ26825120
Leukocyte driven-decidual angiogenesis in early pregnancyQ26851470
Placental Protein 13 (PP13) - A Placental Immunoregulatory Galectin Protecting PregnancyQ26861380
A leading role for the immune system in the pathophysiology of preeclampsiaQ27003069
Modulation of neutrophil NETosis: interplay between infectious agents and underlying host physiologyQ27693200
Galectins: Double-edged Swords in the Cross-roads of Pregnancy Complications and Female Reproductive Tract Inflammation and NeoplasiaQ28081459
Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiencyQ28216587
Functional analyses of placental protein 13/galectin-13Q28249207
Purification and characterization of two new soluble placental tissue proteins (PP13 and PP17)Q28275001
Decidual lymphocytes of human spontaneous abortions induce apoptosis but not necrosis in JEG-3 extravillous trophoblast cells.Q40701583
Changes in T Cell and Dendritic Cell Phenotype from Mid to Late Pregnancy Are Indicative of a Shift from Immune Tolerance to Immune ActivationQ41665214
Differential expression of Galectin-1 and Galectin-3 during first trimester human embryogenesisQ42443034
Placenta-derived soluble MHC class I chain-related molecules down-regulate NKG2D receptor on peripheral blood mononuclear cells during human pregnancy: a possible novel immune escape mechanism for fetal survival.Q42491660
Fas ligand mediates activation-induced cell death in human T lymphocytesQ42942730
Interleukin-1 alpha and interleukin-1 beta in preterm and term human parturitionQ44937474
Dimeric galectin-1 induces IL-10 production in T-lymphocytes: an important tool in the regulation of the immune responseQ45147481
Effects of placental protein 13 on the cardiovascular system in gravid and non-gravid rodentsQ45783688
Comparative analysis of maternal-fetal interface in preeclampsia and preterm labor.Q45985749
Apoptosis of T cells mediated by galectin-1.Q46356564
A pivotal role for galectin-1 in fetomaternal toleranceQ46891030
Human Chorionic Gonadotropin as a Pivotal Endocrine Immune Regulator Initiating and Preserving Fetal ToleranceQ47109145
Circulating angiogenic factors and the risk of preeclampsiaQ47217679
Recruitment of transferrin receptor to immunological synapse in response to TCR engagementQ47579077
VEGF and VEGFR1 levels in different regions of the normal and preeclampsia placentaeQ47997086
Progesterone-induced blocking factor (PIBF) modulates cytokine production by lymphocytes from women with recurrent miscarriage or preterm deliveryQ47997242
The role of indoleamine-2,3-dioxygenase in normal and pathological pregnanciesQ48272907
Life and Death of Activated T Cells: How Are They Different from Naïve T Cells?Q49636303
Innate lymphoid cells at the human maternal-fetal interface in spontaneous preterm laborQ49861059
The role of decidual immune cells on human pregnancy.Q50064264
The inflammation paradox in the evolution of mammalian pregnancy: turning a foe into a friendQ50280596
Pro- and antiinflammatory cytokines in threatened miscarriagesQ83938012
Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell deathQ84391873
First‐trimester placental protein 13 and placental growth factor: markers for identification of women destined to develop early‐onset pre‐eclampsiaQ85029222
Prediction of preeclampsia by placental protein 13 and background risk factors and its prevention by aspirinQ87415142
Innate and adaptive immune interactions at the fetal-maternal interface in healthy human pregnancy and pre-eclampsiaQ37683540
Immune regulation of conception and embryo implantation-all about quality control?Q37720005
Th1/Th2/Th17 and regulatory T-cell paradigm in pregnancyQ37747554
Physiologic Uterine Inflammation and Labor Onset: Integration of Endocrine and Mechanical SignalsQ38012004
First trimester serum markers to predict preeclampsiaQ38020351
Interleukin-6 in pregnancy and gestational disordersQ38028200
Mechanisms of T cell tolerance towards the allogeneic fetusQ38067209
Immune balance at the foeto-maternal interface as the fulcrum of reproductive successQ38083842
Fetomaternal immune cross-talk and its consequences for maternal and offspring's healthQ38104878
Galectin signature in normal pregnancy and preeclampsiaQ38129503
Understanding the complexity of the immune system during pregnancy.Q38226317
Evolving mechanistic insights into galectin functionsQ38254055
Abnormal blood biomarkers in early pregnancy are associated with preeclampsia: a meta-analysisQ38259145
Expression of galectin-1, -3 (gal-1, gal-3) and the Thomsen-Friedenreich (TF) antigen in normal, IUGR, preeclamptic and HELLP placentasQ38299585
Galectins bind to the multivalent glycoprotein asialofetuin with enhanced affinities and a gradient of decreasing binding constantsQ38321186
Galectins in angiogenesis: consequences for gestationQ38333109
CD25 blockade protects T cells from activation-induced cell death (AICD) via maintenance of TOSO expressionQ38351173
Decidual cytokines and pregnancy complications: focus on spontaneous miscarriageQ38378099
The American College of Obstetricians and Gynecologists Practice Bulletin no. 150. Early pregnancy lossQ38453417
The Paternal Contribution to Fetal ToleranceQ38547913
Molecular Cross-Talk at the Feto-Maternal InterfaceQ38589205
An immune clock of human pregnancy.Q38597262
To serve and to protect: the role of decidual innate immune cells on human pregnancyQ38634374
Embryo implantation evolved from an ancestral inflammatory attachment reactionQ38659288
Immunological implications of pregnancy-induced microchimerism.Q38686693
The T helper type 17/regulatory T cell paradigm in pregnancyQ38725966
Pathophysiology of preeclampsia: an angiogenic imbalance and long-lasting systemic vascular dysfunctionQ38796954
Tim-3: Expression on immune cells and roles at the maternal-fetal interfaceQ38803020
Placental Protein 13 Administration to Pregnant Rats Lowers Blood Pressure and Augments Fetal Growth and Venous RemodelingQ38969936
HLA-G: At the Interface of Maternal-Fetal ToleranceQ39171643
Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancyQ39273203
Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss.Q39321607
Sampling and Definitions of Placental Lesions: Amsterdam Placental Workshop Group Consensus Statement.Q39737414
Up-and-down immunity of pregnancy in humans.Q40092856
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell deathQ40333858
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunityQ28281686
Mother's little helpers: mechanisms of maternal-fetal toleranceQ28297770
Orchestration of angiogenesis by immune cellsQ28389236
PP13, maternal ABO blood groups and the risk assessment of pregnancy complicationsQ28742192
Cloning and expression of a novel human galectin cDNA, predominantly expressed in placenta(1).Q30706429
Multimodal Regulation of NET Formation in Pregnancy: Progesterone Antagonizes the Pro-NETotic Effect of Estrogen and G-CSFQ30830726
VEGFR1 and VEGFR2 involvement in extracellular galectin-1- and galectin-3-induced angiogenesisQ31121321
Proteomic analysis on the alteration of protein expression in the placental villous tissue of early pregnancy lossQ33245316
Endocrine factors modulating immune responses in pregnancyQ33611653
Innate immune system and preeclampsiaQ33658840
Characteristic Changes in Decidual Gene Expression Signature in Spontaneous Term ParturitionQ33729663
The change in concentrations of angiogenic and anti-angiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the subsequent development of preeclampsia and small-for-gestational age.Q33755648
Gestational Diabetes Mellitus Is Associated with Altered Neutrophil ActivityQ33794472
Maternal plasma concentrations of angiogenic/antiangiogenic factors in the third trimester of pregnancy to identify the patient at risk for stillbirth at or near term and severe late preeclampsiaQ33863973
Immune surveillance of the maternal/fetal interface: controversies and implicationsQ33940662
Dysregulated complement activation as a common pathway of injury in preeclampsia and other pregnancy complicationsQ33976312
Galectinomics: finding themes in complexityQ34148905
Gimme shelter: the immune system during pregnancyQ34177939
Preterm labor: one syndrome, many causesQ34314824
Evolutionary origins of the placental expression of chromosome 19 cluster galectins and their complex dysregulation in preeclampsiaQ34372600
Immune cells in term and preterm laborQ34455630
Recent Insight into the Role of the PD-1/PD-L1 Pathway in Feto-Maternal Tolerance and PregnancyQ34460789
Trophoblast-microbiome interaction: a new paradigm on immune regulation.Q34496498
Normal pregnancy is characterized by systemic activation of the complement systemQ34499492
Evolution of non-cytotoxic uterine natural killer cellsQ34590583
First-trimester placental protein 13 screening for preeclampsia and intrauterine growth restrictionQ34647428
Neutrophil NETs: a novel contributor to preeclampsia-associated placental hypoxia?Q34648192
IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesisQ34648364
HLA Class Ib Molecules and Immune Cells in Pregnancy and PreeclampsiaQ34763454
Inflammation and pregnancy: the role of the immune system at the implantation siteQ34806659
Natural killer cells and pregnancyQ34810250
Peripheral blood TIM-3 positive NK and CD8+ T cells throughout pregnancy: TIM-3/galectin-9 interaction and its possible role during pregnancyQ35126662
Interleukin-10: a pleiotropic regulator in pregnancyQ35243821
Recurrent Pregnancy Loss through the Lens of ImmunologyQ35276432
CD8+ effector T cells at the fetal-maternal interface, balancing fetal tolerance and antiviral immunity.Q37014401
Glycobiology simplified: diverse roles of glycan recognition in inflammationQ37111287
Inflammation and pregnancy: the role of toll-like receptors in trophoblast-immune interactionQ37149772
Potential markers of preeclampsia--a reviewQ37278804
Tolerance to noninherited maternal antigens, reproductive microchimerism and regulatory T cell memory: 60 years after 'Evidence for actively acquired tolerance to Rh antigens'.Q37337149
Severe preeclampsia is characterized by increased placental expression of galectin-1Q37416956
Placental protein 13 (galectin-13) has decreased placental expression but increased shedding and maternal serum concentrations in patients presenting with preterm pre-eclampsia and HELLP syndrome.Q37416997
Preeclampsia and small-for-gestational age are associated with decreased concentrations of a factor involved in angiogenesis: soluble Tie-2.Q37428029
Galectin-1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 functionQ37434727
Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammationQ37443866
First-trimester maternal serum PP13 in the risk assessment for preeclampsia.Q37444801
Microarray profiling reveals that placental transcriptomes of early-onset HELLP syndrome and preeclampsia are similarQ37567589
Immunoregulatory molecules in human placentas: potential for diverse roles in pregnancyQ37598149
Changes of placental syndecan-1 expression in preeclampsia and HELLP syndromeQ37612423
Evidence of an imbalance of angiogenic/antiangiogenic factors in massive perivillous fibrin deposition (maternal floor infarction): a placental lesion associated with recurrent miscarriage and fetal deathQ37612429
Activating T regulatory cells for tolerance in early pregnancy - the contribution of seminal fluidQ37624139
Lectins as pattern recognition molecules: the effects of epitope density in innate immunityQ37638925
The role of chemokines in term and premature rupture of the fetal membranes: a reviewQ37678741
Predicting the Risk to Develop Preeclampsia in the First Trimester Combining Promoter Variant -98A/C of LGALS13 (Placental Protein 13), Black Ethnicity, Previous Preeclampsia, Obesity, and Maternal Age.Q50879778
Binding characteristics of galectin-3 fusion proteins.Q50944219
Placental protein 13 (PP13)-induced vasodilation of resistance arteries from pregnant and nonpregnant rats occurs via endothelial-signaling pathwaysQ50992588
Maternal lymphocyte subpopulations (CD45RA+ and CD45RO+) in preeclampsiaQ52009983
Maternal-fetal cross talk through cell-free fetal DNA, telomere shortening, microchimerism, and inflammation.Q52632153
Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.Q53279655
Activation of villous trophoblastic p38 and ERK1/2 signaling pathways in preterm preeclampsia and HELLP syndromeQ53639289
Changes in the distribution pattern of galectin-1 and galectin-3 in human placenta correlates with the differentiation pathways of trophoblastsQ53754044
Meta-Analysis of Maternal and Fetal Transcriptomic Data Elucidates the Role of Adaptive and Innate Immunity in Preterm BirthQ55011065
Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell deathQ56169018
Placental Protein 13 and Decidual Zones of Necrosis: An Immunologic Diversion That May be Linked to PreeclampsiaQ56794716
Disruption in the Regulation of Immune Responses in the Placental Subtype of PreeclampsiaQ56996369
Regulatory T cells in embryo implantation and the immune response to pregnancyQ57057008
Tumor necrosis factor in preterm and term labor.Q57081409
Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent PregnanciesQ57083113
Immune Cells at the Fetomaternal Interface: How the Microenvironment Modulates Immune Cells To Foster Fetal DevelopmentQ57260799
The anti-inflammatory limb of the immune response in preterm labor, intra-amniotic infection/inflammation, and spontaneous parturition at term: A role for interleukin-10Q58417804
Antibodies: The major participants in maternal-fetal interactionQ58588673
Clonally Expanded Decidual Effector Regulatory T Cells Increase in Late Gestation of Normal Pregnancy, but Not in Preeclampsia, in HumansQ58705281
Galectin-9 binds IgM-BCR to regulate B cell signalingQ58770912
Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycansQ58771173
Human Innate Lymphoid Cells: Their Functional and Cellular Interactions in DeciduaQ58781730
Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of PreeclampsiaQ58795465
Dynamic changes in maternal decidual leukocyte populations from first to second trimester gestationQ60793578
Identification of a Novel Neutrophil Population: Proangiogenic Granulocytes in Second-Trimester Human DeciduaQ60793580
The Role of Extracellular Vesicles and PIBF in Embryo-Maternal Immune-InteractionsQ60956644
Neutrophil attractant/activating peptide-1/interleukin-8: association with histologic chorioamnionitis, preterm delivery, and bioactive amniotic fluid leukoattractantsQ61845768
Peripheral blood galectin-1-expressing T and natural killer cells in normal pregnancy and preeclampsiaQ63441869
Immune Checkpoint Molecules in Reproductive ImmunologyQ64102290
Placental protein 13 (PP13) stimulates rat uterine vessels after slow subcutaneous administrationQ64112776
Mechanisms of growth inhibition by anti-transferrin receptor monoclonal antibodiesQ70126722
A progesterone-dependent immunomodulatory protein alters the Th1/Th2 balanceQ71717342
Trophoblasts express Fas ligand: a proposed mechanism for immune privilege in placenta and maternal invasionQ73691401
Galectin-1 and -3 in cells of the first trimester placental bedQ74510168
An innate view of human pregnancyQ77326117
Human cell surface glycoprotein related to cell proliferation is the receptor for transferrinQ35362960
Best practice no 178. Examination of the human placenta.Q35587870
First Trimester Pregnancy Loss and the Expression of Alternatively Spliced NKp30 Isoforms in Maternal Blood and Placental Tissue.Q35669969
Macrophages and apoptotic cell clearance during pregnancyQ35814538
Impact of Exogenous Galectin-9 on Human T Cells: CONTRIBUTION OF THE T CELL RECEPTOR COMPLEX TO ANTIGEN-INDEPENDENT ACTIVATION BUT NOT TO APOPTOSIS INDUCTION.Q35860538
Placental oxidative stress: from miscarriage to preeclampsiaQ35879133
Tim-3 Is Upregulated in NK Cells during Early Pregnancy and Inhibits NK Cytotoxicity toward Trophoblast in Galectin-9 Dependent PathwayQ35898865
Galectins as self/non-self recognition receptors in innate and adaptive immunity: an unresolved paradox.Q36093631
HLA-G and immune tolerance in pregnancyQ36109416
B7 family molecules as regulators of the maternal immune system in pregnancyQ36185034
Is the trophoblast an immune regulator? The role of Toll-like receptors during pregnancyQ36259491
Evidence of perturbations of the cytokine network in preterm laborQ36372845
Neutrophil NETs in reproduction: from infertility to preeclampsia and the possibility of fetal lossQ36424780
Placental protein 13 (PP13/galectin-13) undergoes lipid raft-associated subcellular redistribution in the syncytiotrophoblast in preterm preeclampsia and HELLP syndrome.Q36480074
The role of regulatory T cells in alloantigen toleranceQ36563567
CXCL10/IP-10: a missing link between inflammation and anti-angiogenesis in preeclampsia?Q36676660
Evidence for a role for the adaptive immune response in human term parturitionQ36692481
Genetic communication between fetus and mother: short- and long-term consequencesQ36778092
The role of the immune system in preeclampsiaQ36791219
Immunology of pregnancy: cellular mechanisms allowing fetal survival within the maternal uterusQ36802749
Neutrophil migration into the placenta: Good, bad or deadly?Q36857949
Dendritic cells: key to fetal tolerance?Q36862971
Regulatory T cells and regulatory natural killer (NK) cells play important roles in feto-maternal toleranceQ36875737
Role of placentally produced inflammatory and regulatory cytokines in pregnancy and the etiology of preeclampsiaQ36875755
Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells.Q36903097
Natural killer (NK) cells from killers to regulators: distinct features between peripheral blood and decidual NK cellsQ36903104
Emergence of hormonal and redox regulation of galectin-1 in placental mammals: implication in maternal-fetal immune toleranceQ36915292
Prototype and Chimera-Type Galectins in Placentas with Spontaneous and Recurrent MiscarriagesQ36939136
Preeclampsia and angiogenic imbalanceQ36971766
Placental pathology: a systematic approach with clinical correlationsQ36976570
A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a smaQ36984261
T cell apoptosis at the maternal-fetal interface in early human pregnancy, involvement of galectin-1.Q36985070
Interfering with Gal-1-mediated angiogenesis contributes to the pathogenesis of preeclampsiaQ37010679
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)1240
P577publication date2019-06-19
P1433published inFrontiers in ImmunologyQ27723748
P1476titlePlacental Galectins Are Key Players in Regulating the Maternal Adaptive Immune Response
P478volume10

Reverse relations

cites work (P2860)
Q92320999A versatile modular vector set for optimizing protein expression among bacterial, yeast, insect and mammalian hosts
Q90113804Identification of Structural Variation in Chimpanzees Using Optical Mapping and Nanopore Sequencing
Q92142500In vitro fertilization and embryo transfer alter human placental function through trophoblasts in early pregnancy
Q90164356Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape
Q89965744Placental Protein 13 (Galectin-13) Polarizes Neutrophils Toward an Immune Regulatory Phenotype
Q97521548Regulatory T Cells in Pregnancy: It Is Not All About FoxP3

Search more.