δ C-H (hetero)arylation via Cu-catalyzed radical relay

scientific article published on 09 November 2018

δ C-H (hetero)arylation via Cu-catalyzed radical relay is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1039/C8SC04366C
P932PMC publication ID6349054
P698PubMed publication ID30774920

P50authorDavid A. NagibQ42293165
Zuxiao ZhangQ85487357
Leah M StatemanQ114531200
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Direct C(sp3)-H Cross Coupling Enabled by Catalytic Generation of Chlorine Radicals.Q40818908
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Pd-Catalyzed γ-C(sp3)-H Arylation of Free Amines Using a Transient Directing GroupQ43980973
Intramolecular hydrogen abstraction reaction promoted by N-radicals in carbohydrates. Synthesis of chiral 7-oxa-2-azabicyclo[2.2.1]heptane and 8-oxa-6-azabicyclo[3.2.1]octane ring systemsQ44296814
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Catalytic alkylation of remote C-H bonds enabled by proton-coupled electron transferQ47108193
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Copper-catalyzed remote (δ) C(sp3)-H bond amination: a practical strategy to construct pyrrolidine derivatives.Q48160580
Directed γ-C(sp3)-H Alkylation of Carboxylic Acid Derivatives through Visible Light Photoredox CatalysisQ48205331
General, Auxiliary-Enabled Photoinduced Pd-Catalyzed Remote Desaturation of Aliphatic AlcoholsQ48220526
Asymmetric Cu-Catalyzed Intermolecular Trifluoromethylarylation of Styrenes: Enantioselective Arylation of Benzylic RadicalsQ48223918
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Feedstocks to Pharmacophores: Cu-Catalyzed Oxidative Arylation of Inexpensive Alkylarenes Enabling Direct Access to Diarylalkanes.Q48363687
α-Aminoxy-Acid-Auxiliary-Enabled Intermolecular Radical γ-C(sp3 )-H Functionalization of KetonesQ48367334
Sulfamate Esters Guide Selective Radical-Mediated Chlorination of Aliphatic C-H BondsQ48374886
Catalytic Asymmetric Csp3 -H Functionalization under Photoredox Conditions by Radical Translocation and Stereocontrolled Alkene AdditionQ49027736
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An Iodine-Catalyzed Hofmann-Löffler Reaction.Q50972067
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Second-Generation Palladium Catalyst System for Transannular C-H Functionalization of Azabicycloalkanes.Q52590108
Site-Selective δ-C(sp3 )-H Alkylation of Amino Acids and Peptides with Maleimides via a Six-Membered Palladacycle.Q52631370
Ligand-Enabled γ-C(sp3)-H Activation of Ketones.Q52685327
Visible-light-promoted remote C(sp(3))-H amidation and chlorination.Q53268699
Highly efficient syntheses of azetidines, pyrrolidines, and indolines via palladium catalyzed intramolecular amination of C(sp3)-H and C(sp2)-H bonds at γ and δ positions.Q53393802
Visible-Light-Mediated Remote Aliphatic C-H Functionalizations through a 1,5-Hydrogen Transfer Cascade.Q53684066
Site-selective bromination of sp3 C-H bonds.Q53831835
β C–H di-halogenation via iterative hydrogen atom transfer† †Electronic supplementary information (ESI) available. CCDC 1581032. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8sc01214h.Q54998743
Chemo- and regioselective oxygenation of C(sp3)-H bonds in aliphatic alcohols using a covalently bound directing activator and atmospheric oxygen.Q55287312
Primary, Secondary, and Tertiary γ-C(sp)-H Vinylation of Amides via Organic Photoredox-Catalyzed Hydrogen Atom TransferQ56984794
A highly site-selective radical sp C-H amination of azaheterocyclesQ57496225
Diverse secondary C(sp)-H bond functionalization site-selective trifluoroacetoxylation of aliphatic aminesQ57496659
Site-Selective Remote Radical C−H Functionalization of Unactivated C−H Bonds in Amides Using Sulfone ReagentsQ59222715
Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen RadicalsQ60494093
Fluorine transfer to alkyl radicalsQ83413068
Iron-catalyzed C-C bond formation at alpha-position of aliphatic amines via C-H bond activation through 1,5-hydrogen transferQ83980131
Palladium-catalyzed picolinamide-directed alkylation of unactivated C(sp3)-H bonds with alkyl iodidesQ85958043
Generation of Alkoxyl Radicals by Photoredox Catalysis Enables Selective C(sp(3))-H Functionalization under Mild Reaction ConditionsQ86932953
Site-Selective Alkenylation of δ-C(sp(3))-H Bonds with Alkynes via a Six-Membered PalladacycleQ88137615
Iron-Catalyzed, Fluoroamide-Directed C-H FluorinationQ88429547
Remote C-H Functionalization via Selective Hydrogen Atom TransferQ88654204
Regio- and chemoselective Csp3-H arylation of benzylamines by single electron transfer/hydrogen atom transfer synergistic catalysisQ90442645
Photoredox-Catalyzed Intermolecular Remote C-H and C-C Vinylation via Iminyl RadicalsQ91098596
Copper-Catalyzed Radical Relay for Asymmetric Radical TransformationsQ91295179
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue4
P304page(s)1207-1211
P577publication date2018-11-09
P1433published inChemical ScienceQ2962267
P1476titleδ C-H (hetero)arylation via Cu-catalyzed radical relay
P478volume10

Reverse relations

cites work (P2860)
Q91933120Copper-catalyzed enantioselective Sonogashira-type oxidative cross-coupling of unactivated C(sp3)-H bonds with alkynes
Q96816615Dual electrocatalysis enables enantioselective hydrocyanation of conjugated alkenes
Q92823683Functionalization of remote C(sp3)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes
Q92485985Practical, metal-free remote heteroarylation of amides via unactivated C(sp3)-H bond functionalization
Q64275248Primary α-tertiary amine synthesis α-C-H functionalization
Q90811707Site-selective remote C(sp3)-H heteroarylation of amides via organic photoredox catalysis
Q90105996Vicinal, Double C-H Functionalization of Alcohols via an Imidate Radical-Polar Crossover Cascade
Q90187399Visible-Light-Induced Palladium-Catalyzed Generation of Aryl Radicals from Aryl Triflates
Q90470809Visible-light promoted regioselective amination and alkylation of remote C(sp3)-H bonds

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