scholarly article | Q13442814 |
P356 | DOI | 10.1002/CMDC.201900604 |
P698 | PubMed publication ID | 31808981 |
P50 | author | Stefan Geschwindner | Q87739999 |
Gerhard Klebe | Q87855685 | ||
Andreas Heine | Q89174405 | ||
Engi Hassaan | Q91753278 | ||
Per-Olof Eriksson | Q91753294 | ||
P2860 | cites work | Theory for electrostatic interaction chromatography of proteins | Q52422741 |
XDSAPP: a graphical user interface for the convenient processing of diffraction data usingXDS | Q57973386 | ||
Nuclear magnetic resonance of paramagnetic metalloproteins | Q57975839 | ||
Introduction to protein crystallization | Q58287960 | ||
Improving biosensor analysis | Q73170565 | ||
High-affinity inhibitors of Zymomonas mobilis tRNA-guanine transglycosylase through convergent optimization | Q87350725 | ||
PHENIX: a comprehensive Python-based system for macromolecular structure solution | Q24654617 | ||
A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase | Q27629578 | ||
Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies | Q27648851 | ||
An integrative approach combining noncovalent mass spectrometry, enzyme kinetics and X-ray crystallography to decipher Tgt protein-protein and protein-RNA interaction | Q27656669 | ||
Crystal packing modifies ligand binding affinity: The case of aldose reductase | Q27670601 | ||
A small nonrule of 3 compatible fragment library provides high hit rate of endothiapepsin crystal structures with various fragment chemotypes | Q27674738 | ||
Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor | Q27678289 | ||
Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery | Q27679154 | ||
What Glues a Homodimer Together: Systematic Analysis of the Stabilizing Effect of an Aromatic Hot Spot in the Protein-Protein Interface of the tRNA-Modifying Enzyme Tgt | Q27700741 | ||
XDS | Q27860472 | ||
Coot: model-building tools for molecular graphics | Q27860505 | ||
Phasercrystallographic software | Q27860930 | ||
The CCP4 suite: programs for protein crystallography | Q27861090 | ||
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density | Q29578786 | ||
Soaking suggests "alternative facts": Only co-crystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-of-inhibition | Q33574433 | ||
A ‘Rule of Three’ for fragment-based lead discovery? | Q33973131 | ||
Fragment-based approaches in drug discovery and chemical biology | Q34303994 | ||
Learning from our mistakes: the 'unknown knowns' in fragment screening | Q34657185 | ||
A three-stage biophysical screening cascade for fragment-based drug discovery. | Q35025905 | ||
One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists | Q35741775 | ||
Site-specific modification of Shigella flexneri virF mRNA by tRNA-guanine transglycosylase in vitro | Q35945409 | ||
vacC, a virulence-associated chromosomal locus of Shigella flexneri, is homologous to tgt, a gene encoding tRNA-guanine transglycosylase (Tgt) of Escherichia coli K-12 | Q35967502 | ||
Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library | Q36006936 | ||
Experimental Active-Site Mapping by Fragments: Hot Spots Remote from the Catalytic Center of Endothiapepsin | Q36087260 | ||
The crystallization and structural analysis of cellulases (and other glycoside hydrolases): strategies and tactics | Q38011446 | ||
Fragment-based lead discovery and design | Q38184631 | ||
Proper modelling of ligand binding requires an ensemble of bound and unbound states | Q38746014 | ||
Experiences in fragment-based drug discovery | Q39635128 | ||
Genetic dissection of synthesis and function of modified nucleosides in bacterial transfer RNA. | Q40400715 | ||
A detergent-based assay for the detection of promiscuous inhibitors | Q42007896 | ||
P433 | issue | 3 | |
P304 | page(s) | 324-337 | |
P577 | publication date | 2020-01-29 | |
P1433 | published in | ChemMedChem | Q2962252 |
P1476 | title | Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies | |
P478 | volume | 15 |
Search more.