Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies

scientific article published on 29 January 2020

Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/CMDC.201900604
P698PubMed publication ID31808981

P50authorStefan GeschwindnerQ87739999
Gerhard KlebeQ87855685
Andreas HeineQ89174405
Engi HassaanQ91753278
Per-Olof ErikssonQ91753294
P2860cites workTheory for electrostatic interaction chromatography of proteinsQ52422741
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A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylaseQ27629578
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Crystal packing modifies ligand binding affinity: The case of aldose reductaseQ27670601
A small nonrule of 3 compatible fragment library provides high hit rate of endothiapepsin crystal structures with various fragment chemotypesQ27674738
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One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit ListsQ35741775
Site-specific modification of Shigella flexneri virF mRNA by tRNA-guanine transglycosylase in vitroQ35945409
vacC, a virulence-associated chromosomal locus of Shigella flexneri, is homologous to tgt, a gene encoding tRNA-guanine transglycosylase (Tgt) of Escherichia coli K-12Q35967502
Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment libraryQ36006936
Experimental Active-Site Mapping by Fragments: Hot Spots Remote from the Catalytic Center of EndothiapepsinQ36087260
The crystallization and structural analysis of cellulases (and other glycoside hydrolases): strategies and tacticsQ38011446
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P433issue3
P304page(s)324-337
P577publication date2020-01-29
P1433published inChemMedChemQ2962252
P1476titleFragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies
P478volume15

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