TMEM16F/Anoctamin 6 in Ferroptotic Cell Death

scientific article published on 05 May 2019

TMEM16F/Anoctamin 6 in Ferroptotic Cell Death is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/CANCERS11050625
P932PMC publication ID6562394
P698PubMed publication ID31060306

P50authorKarl KunzelmannQ37377824
P2093author name stringRainer Schreiber
Jiraporn Ousingsawat
P2860cites workAnoctamin 6 is an essential component of the outwardly rectifying chloride channelQ24293563
Anoctamins are a family of Ca2+-activated Cl- channelsQ24297964
Calcium-dependent phospholipid scrambling by TMEM16FQ24308774
Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophagesQ24317531
X-ray structure of a calcium-activated TMEM16 lipid scramblaseQ27696163
Organizing cell renewal in the intestine: stem cells, signals and combinatorial controlQ28235109
Inhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell LinesQ28546722
TMEM16A confers receptor-activated calcium-dependent chloride conductanceQ28590097
TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulationQ28590146
Expression and function of epithelial anoctaminsQ28591748
Expression cloning of TMEM16A as a calcium-activated chloride channel subunitQ33370813
Ferroptosis: an iron-dependent form of nonapoptotic cell deathQ34032093
Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosisQ34389482
Synchronized renal tubular cell death involves ferroptosis.Q34447203
Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugsQ34500340
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activityQ34821709
Anoctamin 6 regulates C2C12 myoblast proliferationQ35129361
Identification of a lipid scrambling domain in ANO6/TMEM16F.Q35770512
Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formationQ36246445
Control of TMEM16A by INO-4995 and other inositolphosphatesQ36603234
Anoctamin 1 mediates thermal pain as a heat sensorQ37362045
Molecular functions of anoctamin 6 (TMEM16F): a chloride channel, cation channel, or phospholipid scramblase?Q38113091
Ca2+ signals, cell membrane disintegration, and activation of TMEM16F during necroptosisQ38751325
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.Q38835006
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell deathQ38835009
Differential effects of anoctamins on intracellular calcium signals.Q38968905
Reactive oxygen species and cancer paradox: To promote or to suppress?Q39088944
TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A.Q39816829
TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activationQ40227066
Cell-specific mechanisms of TMEM16A Ca2+-activated chloride channel in cancerQ41283473
TMEM16F is a component of a Ca2+-activated Cl- channel but not a volume-sensitive outwardly rectifying Cl- channelQ45063506
Activation of the phospholipid scramblase TMEM16F by nanosecond pulsed electric fields (nsPEF) facilitates its diverse cytophysiological effectsQ45069386
Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.Q45880051
Cryo-EM structures of the TMEM16A calcium-activated chloride channel.Q46064411
Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca2+ and plasma membrane lipid.Q46261929
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and DiseaseQ46292537
CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6).Q46311552
Involvement of Ca2+ Activated Cl- Channel Ano6 in Platelet Activation and ApoptosisQ46637282
Characterization of the scrambling domain of the TMEM16 family.Q47162029
Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.Q47297806
TMEM16A/ANO1 Inhibits Apoptosis Via Downregulation of Bim ExpressionQ47814662
Cellular volume regulation by anoctamin 6: Ca²⁺, phospholipase A2 and osmosensingQ48567890
Contribution of TMEM16F to pyroptotic cell deathQ49789944
Relationship between TMEM16A/anoctamin 1 and LRRC8A.Q51577479
Rapid onset of apoptosis in vitro follows disruption of beta 1-integrin/matrix interactions in human colonic crypt cells.Q52523025
Single-molecule analysis of phospholipid scrambling by TMEM16F.Q55312949
Inhibition of ANO1/TMEM16A induces apoptosis in human prostate carcinoma cells by activating TNF-α signaling.Q55402499
TMEM16F activation by Ca triggers plasma membrane expansion and directs PD-1 traffickingQ61444675
Contribution of Anoctamins to Cell Survival and Cell DeathQ64074267
Ferroptosis, a new form of cell death: opportunities and challenges in cancerQ64103562
Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EMQ64118581
Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16FQ64262476
Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial SepsisQ89222822
High expression of leucine‑rich repeat‑containing 8A is indicative of a worse outcome of colon cancer patients by enhancing cancer cell growth and metastasisQ90278193
TMEM16A is indispensable for basal mucus secretion in airways and intestineQ90756958
Lipid Peroxidation Drives Renal Cyst Growth In Vitro through Activation of TMEM16AQ90870301
Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantationQ92109247
Plasma membrane-localized TMEM16 proteins are indispensable for expression of CFTRQ92641332
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue5
P921main subjectcell deathQ2383867
P577publication date2019-05-05
P1433published inCancersQ27722963
P1476titleTMEM16F/Anoctamin 6 in Ferroptotic Cell Death
P478volume11

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cites work (P2860)
Q91173363FTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia
Q91595744The clearance of dead cells by efferocytosis
Q90355975The interactome of the prostate-specific protein Anoctamin 7

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