| scholarly article | Q13442814 |
| P50 | author | Hong-Gang Wang | Q37383478 |
| P2093 | author name string | Chong Chen | |
| Megan M Young | |||
| Van Bui | |||
| P2860 | cites work | Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells | Q24307778 |
| FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells | Q24650419 | ||
| Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles | Q24657869 | ||
| The emerging role of FTY720 (Fingolimod) in cancer treatment | Q26748927 | ||
| Asymmetrical Lipid Bilayer Structure for Biological Membranes | Q28242238 | ||
| Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis | Q28271008 | ||
| Lipid somersaults: Uncovering the mechanisms of protein-mediated lipid flipping | Q28395224 | ||
| The dynamin chemical inhibitor dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages | Q28478474 | ||
| Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720 | Q28512961 | ||
| FTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levels | Q28541065 | ||
| A novel aminophospholipid transporter exclusively expressed in spermatozoa is required for membrane lipid asymmetry and normal fertilization | Q28592533 | ||
| Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists | Q29618071 | ||
| Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1 | Q29619644 | ||
| Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking | Q30275525 | ||
| Phosphatidylserine flipping enhances membrane curvature and negative charge required for vesicular transport. | Q30544961 | ||
| Annexin V binds to positively selected B cells | Q31724311 | ||
| FTY720 Induces Autophagy-Associated Apoptosis in Human Oral Squamous Carcinoma Cells, in Part, through a Reactive Oxygen Species/Mcl-1-Dependent Mechanism | Q33912023 | ||
| The asymmetric distribution of phospholipids in the human red cell membrane. A combined study using phospholipases and freeze-etch electron microscopy | Q34052053 | ||
| Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers | Q34104555 | ||
| FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells | Q34162587 | ||
| Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability. | Q34227743 | ||
| The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2 | Q34274256 | ||
| Membrane microparticles: two sides of the coin | Q34384910 | ||
| Phospholipid scramblase, a new effector of FcepsilonRI signaling in mast cells | Q34825351 | ||
| A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells | Q35045183 | ||
| ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles | Q35148002 | ||
| Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase. | Q35192746 | ||
| Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia | Q35212369 | ||
| Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis | Q35874532 | ||
| A systematic evaluation of the safety and toxicity of fingolimod for its potential use in the treatment of acute myeloid leukaemia. | Q35953902 | ||
| Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins | Q36266670 | ||
| Acute cholesterol depletion inhibits clathrin-coated pit budding | Q36380759 | ||
| FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma | Q36384629 | ||
| Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis | Q36602177 | ||
| Ceramide starves cells to death by downregulating nutrient transporter proteins | Q36971061 | ||
| Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways | Q37395800 | ||
| The antineoplastic properties of FTY720: evidence for the repurposing of fingolimod | Q38546700 | ||
| Phosphatidylserine externalization, "necroptotic bodies" release, and phagocytosis during necroptosis | Q38699026 | ||
| Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking | Q38723111 | ||
| Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo | Q38812925 | ||
| Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure | Q38987723 | ||
| FTY720 induces apoptosis of chronic myelogenous leukemia cells via dual activation of BIM and BID and overcomes various types of resistance to tyrosine kinase inhibitors | Q39126141 | ||
| Autophagy induced by FTY720 promotes apoptosis in U266 cells | Q39405613 | ||
| Reactivating PP2A by FTY720 as a novel therapy for AML with C-KIT tyrosine kinase domain mutation | Q39438493 | ||
| The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane | Q39453507 | ||
| FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells. | Q39565401 | ||
| FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: a protective role of autophagy. | Q39645996 | ||
| Antigen recognition induces phosphatidylserine exposure on the cell surface of human CD8+ T cells | Q40243201 | ||
| Effects of Bafilomycin A1: an inhibitor of vacuolar H (+)-ATPases on endocytosis and apoptosis in RAW cells and RAW cell-derived osteoclasts | Q40662486 | ||
| The immune modulator FTY720 targets sphingosine 1-phosphate receptors | Q40736684 | ||
| Immunologic stimulation of mast cells leads to the reversible exposure of phosphatidylserine in the absence of apoptosis | Q40838147 | ||
| Annexin V binds to viable B cells and colocalizes with a marker of lipid rafts upon B cell receptor activation | Q40905062 | ||
| MICAL-L1: An unusual Rab effector that links EHD1 to tubular recycling endosomes | Q41297679 | ||
| ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences | Q42801479 | ||
| Phosphatidylserine is a marker of tumor vasculature and a potential target for cancer imaging and therapy | Q44234512 | ||
| The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors | Q44722923 | ||
| Viable, apoptotic and necrotic monocytes expose phosphatidylserine: cooperative binding of the ligand Annexin V to dying but not viable cells and implications for PS-dependent clearance | Q45148233 | ||
| The Sphingosine-1-Phosphate Modulator FTY720 Targets Multiple Myeloma via the CXCR4/CXCL12 Pathway | Q45858841 | ||
| The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity | Q46249644 | ||
| Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca2+ and plasma membrane lipid. | Q46261929 | ||
| Effects of stereochemistry, saturation, and hydrocarbon chain length on the ability of synthetic constrained azacyclic sphingolipids to trigger nutrient transporter down-regulation, vacuolation, and cell death | Q46375326 | ||
| Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes | Q46604990 | ||
| Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization | Q46882679 | ||
| TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition | Q49714600 | ||
| Contribution of TMEM16F to pyroptotic cell death | Q49789944 | ||
| Annexin V staining due to loss of membrane asymmetry can be reversible and precede commitment to apoptotic death. | Q50517430 | ||
| Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis. | Q52545447 | ||
| Pb(II) Induces Scramblase Activation and Ceramide-Domain Generation in Red Blood Cells. | Q55054813 | ||
| Phosphatidylserine exposure in B lymphocytes: a role for lipid packing | Q57374987 | ||
| Three cell deaths and a funeral: macrophage clearance of cells undergoing distinct modes of cell death | Q61797350 | ||
| Sphingolipids inhibit endosomal recycling of nutrient transporters by inactivating ARF6. | Q64986290 | ||
| Enhancement of endocytosis due to aminophospholipid transport across the plasma membrane of living cells | Q74590841 | ||
| Study of aqueous phase aggregation of FTY720 (fingolimod hydrochloride) and its effect on DMPC liposomes using fluorescent molecular probes | Q85947780 | ||
| TMEM16F/Anoctamin 6 in Ferroptotic Cell Death | Q91796465 | ||
| The NMR-based characterization of the FTY720-SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET-PP2A interaction | Q92651386 | ||
| Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis | Q93015477 | ||
| P433 | issue | 11 | |
| P921 | main subject | acute myeloid leukemia | Q264118 |
| cell death | Q2383867 | ||
| P304 | page(s) | 847 | |
| P577 | publication date | 2019-11-07 | |
| P1433 | published in | Cell Death and Disease | Q2197222 |
| P1476 | title | FTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia | |
| P478 | volume | 10 |
| Q89944283 | The Role of MYC and PP2A in the Initiation and Progression of Myeloid Leukemias | cites work | P2860 |
Search more.