Pioneer and repressive functions of p63 during zebrafish embryonic ectoderm specification

scientific article published on 11 July 2019

Pioneer and repressive functions of p63 during zebrafish embryonic ectoderm specification is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2019NatCo..10.3049S
P356DOI10.1038/S41467-019-11121-Z
P932PMC publication ID6624255
P698PubMed publication ID31296872

P50authorJosé M Santos-PereiraQ91330176
Lourdes Gallardo-FuentesQ91809548
Juan J TenaQ42718731
Rafael D AcemelQ57327008
P2093author name stringAna Neto
P2860cites workModel-based analysis of ChIP-Seq (MACS)Q21183902
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activitiesQ22003973
Yap1 acts downstream of α-catenin to control epidermal proliferationQ24294904
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identitiesQ24617969
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial ImmunityQ24669850
Fast gapped-read alignment with Bowtie 2Q27860699
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
The Sequence Alignment/Map format and SAMtoolsQ27860966
Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndromeQ28146059
ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesisQ28508449
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial developmentQ28587664
p63 is a p53 homologue required for limb and epidermal morphogenesisQ28588206
p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermisQ28590021
p63 is upstream of IKK alpha in epidermal developmentQ28591802
deepTools2: a next generation web server for deep-sequencing data analysisQ28597770
Deep conservation of wrist and digit enhancers in fishQ28651020
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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2Q29547403
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Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4Q29618736
Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium.Q30357806
Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progressionQ58761894
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Single-cell reconstruction of developmental trajectories during zebrafish embryogenesisQ60468467
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage CommitmentQ64117626
Pattern of p63 mutations and their phenotypes--updateQ83324807
p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cellsQ94350528
seqMINER: an integrated ChIP-seq data interpretation platformQ33777909
Split-hand/split-foot malformation is caused by mutations in the p63 gene on 3q27.Q34141916
Pioneer factors: directing transcriptional regulators within the chromatin environmentQ34212702
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome positionQ34375601
Vertebrate embryonic cells will become nerve cells unless told otherwiseQ34415315
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skinQ34573137
TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activityQ35042948
Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytesQ35460065
ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors.Q35747670
CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivoQ36109068
Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiationQ36180219
p63-associated disorders.Q36708708
p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cellsQ37398481
p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7.Q37431818
SOX2 and p63 colocalize at genetic loci in squamous cell carcinomasQ37680006
Pioneer transcription factors, chromatin dynamics, and cell fate control.Q38716695
Functional Equivalence of the SOX2 and SOX3 Transcription Factors in the Developing Mouse Brain and TestesQ38780139
Mechanism of regulatory target selection by the SOX high-mobility-group domain proteins as revealed by comparison of SOX1/2/3 and SOX9.Q39444324
Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation.Q40879235
A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63Q41312602
Dynamics of enhancer chromatin signatures mark the transition from pluripotency to cell specification during embryogenesis.Q41888953
Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivativesQ41896090
Computational methods to detect conserved non-genic elements in phylogenetically isolated genomes: application to zebrafish.Q42101967
p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation.Q42539520
A dominant-negative form of p63 is required for epidermal proliferation in zebrafish.Q43997050
Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectodermQ43997054
Active DNA demethylation at enhancers during the vertebrate phylotypic periodQ46079460
The UCSC Genome Browser database: 2018 updateQ46557670
Odd-skipped genes encode repressors that control kidney development.Q47070410
Sox3 regulates both neural fate and differentiation in the zebrafish ectodermQ47073163
Master regulatory role of p63 in epidermal development and diseaseQ47286853
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis.Q50027227
Assay for transposase-accessible chromatin and circularized chromosome conformation capture, two methods to explore the regulatory landscapes of genes in zebrafish.Q50496830
Pioneer transcription factors shape the epigenetic landscape.Q50532548
Dnmt3a and Dnmt3b Associate with Enhancers to Regulate Human Epidermal Stem Cell Homeostasis.Q51603894
ΔNp63 is regulated by BMP4 signaling and is required for early epidermal development in Xenopus.Q51835834
TP63 gene mutation in ADULT syndromeQ55670364
Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the SkinQ57294154
Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitmentQ58611498
P433issue1
P304page(s)3049
P577publication date2019-07-11
P1433published inNature CommunicationsQ573880
P1476titlePioneer and repressive functions of p63 during zebrafish embryonic ectoderm specification
P478volume10

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cites work (P2860)
Q97517249Genetic Animal Models for Arrhythmogenic Cardiomyopathy
Q98902645The Dynamics of Epidermal Stratification During Post-larval Development in Zebrafish
Q104739498The power of zebrafish models for understanding the co-occurrence of craniofacial and limb disorders

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