Comparison of ELISA and HPLC-MS methods for the determination of exenatide in biological and biotechnology-based formulation matrices

scientific article published on 26 February 2019

Comparison of ELISA and HPLC-MS methods for the determination of exenatide in biological and biotechnology-based formulation matrices is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.JPHA.2019.02.001
P932PMC publication ID6598173
P698PubMed publication ID31297291

P50authorAmílcar FalcãoQ42629937
Ana FortunaQ43005774
Adriana O. SantosQ45896991
Raquel SeiçaQ47503991
António J. RibeiroQ51128469
P2093author name stringF Veiga
A R Pinho
C Estevens
P2860cites workEffects of the multilayer structures on Exenatide release and bioactivity in microsphere/thermosensitive hydrogel systemQ90271786
A liquid chromatography high-resolution mass spectrometry in vitro assay to assess metabolism at the injection site of subcutaneously administered therapeutic peptidesQ90444913
Pharmacological Signatures of the Exenatide Nanoparticles Complex Against Myocardial Ischemia Reperfusion InjuryQ90757201
A clinical review of GLP-1 receptor agonists: efficacy and safety in diabetes and beyondQ26799389
Advances in targeted proteomics and applications to biomedical researchQ28066912
Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitusQ30249371
Targeted proteomics analysis of protein degradation in plant signaling on an LTQ-Orbitrap mass spectrometer.Q30317151
Simultaneous determination of incretin hormones and their truncated forms from human plasma by immunoprecipitation and liquid chromatography-mass spectrometryQ30320514
Multiplexed MS/MS for improved data-independent acquisitionQ30651066
Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experimentsQ30749426
Use of proteomic patterns in serum to identify ovarian cancerQ30819686
Multiplexed, Scheduled, High-Resolution Parallel Reaction Monitoring on a Full Scan QqTOF Instrument with Integrated Data-Dependent and Targeted Mass Spectrometric WorkflowsQ30996203
Analysis and validation of proteomic data generated by tandem mass spectrometryQ31131394
One-step purification of a fusion protein of glucagon-like peptide-1 and human serum albumin expressed in pichia pastoris by an immunomagnetic separation techniqueQ33305182
Development and validation of a rapid high-performance liquid chromatography method for the quantification of exenatide.Q33705580
Targeted data extraction of the MS/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysisQ34133645
A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis.Q34343581
Liquid Chromatography Mass Spectrometry-Based Proteomics: Biological and Technological AspectsQ34983181
Glucagon-like peptide-1 (GLP-1) analogs: recent advances, new possibilities, and therapeutic implications.Q35087846
Using data-independent, high-resolution mass spectrometry in protein biomarker research: perspectives and clinical applicationsQ35518214
Efficacy and safety of once-weekly glucagon-like peptide 1 receptor agonists for the management of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trialsQ35784245
Mildly acidic conditions eliminate deamidation artifact during proteolysis: digestion with endoprotease Glu-C at pH 4.5.Q35889468
The impact of phospholipids and phospholipid removal on bioanalytical method performanceQ35895799
A liquid chromatography-mass spectrometry assay for quantification of Exendin[9-39] in human plasma.Q35898828
Advancing the sensitivity of selected reaction monitoring-based targeted quantitative proteomicsQ36031629
Synthetic small molecule GLP-1 secretagogues prepared by means of a three-component indole annulation strategyQ36063472
Comprehensive N-Glycan Profiling of Cetuximab Biosimilar Candidate by NP-HPLC and MALDI-MS.Q36245448
Evaluation of an [(18)F]AlF-NOTA Analog of Exendin-4 for Imaging of GLP-1 Receptor in InsulinomaQ36383709
Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitusQ37141727
Glucagon-Like Peptide-1 Receptor Agonists for Type 2 Diabetes: A Clinical Update of Safety and EfficacyQ37402786
Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?Q37470376
Incretin-based therapies for type 2 diabetes mellitusQ37483473
Interleukin-1 receptor antagonist: a new therapy for type 2 diabetes mellitusQ37978230
GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitusQ38040314
Discovery and development of exenatide: the first antidiabetic agent to leverage the multiple benefits of the incretin hormone, GLP-1.Q38066566
Liquid chromatographic methods for the quantification of catecholamines and their metabolites in several biological samples--a reviewQ38087673
Protein-based matrix interferences in ligand-binding assays.Q38211931
Sample preparation strategies for targeted proteomics via proteotypic peptides in human blood using liquid chromatography tandem mass spectrometryQ38270732
Potential side effects to GLP-1 agonists: understanding their safety and tolerabilityQ38286444
Recent advances in targeted proteomics for clinical applicationsQ38287678
Exenatide Extended-Release: An Updated Review of Its Use in Type 2 Diabetes MellitusQ38526870
The value of short- and long-acting glucagon-like peptide-1 agonists in the management of type 2 diabetes mellitus: experience with exenatideQ38599958
In Vivo Target Validation Using Biological Molecules in Drug DevelopmentQ38629068
Treatment potential of the GLP-1 receptor agonists in type 2 diabetes mellitus: a reviewQ38634679
Insulin glargine and its two active metabolites: A sensitive (16pM) and robust simultaneous hybrid assay coupling immunoaffinity purification with LC-MS/MS to support biosimilar clinical studiesQ38636682
Bioanalytical challenge: A review of environmental and pharmaceuticals contaminants in human milk.Q38884195
Sample clean-up strategies for ESI mass spectrometry applications in bottom-up proteomics: Trends from 2012 to 2016.Q38921700
Pharmacokinetic/pharmacodynamic studies on exenatide in diabetic ratsQ39276306
Therapeutic drug monitoring of CT-P13: a comparison of four different immunoassaysQ41078498
Successful Colistin Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infection Using a Rapid Method for Determination of Colistin in Plasma: Usefulness of Therapeutic Drug MonitoringQ41117701
Development of a high-throughput UHPLC-MS/MS (SRM) method for the quantitation of endogenous glucagon from human plasmaQ41656530
In vivo evaluation of an oral self-emulsifying drug delivery system (SEDDS) for exenatideQ88158821
Current Mass Spectrometric Tools for the Bioanalyses of Therapeutic Monoclonal Antibodies and Antibody-Drug ConjugatesQ88334299
The use of low molecular weight protamine to enhance oral absorption of exenatideQ88815505
Recent developments and applications of different sorbents for SPE and SPME from biological samplesQ88936427
Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogsQ43245526
Pharmacokinetics and efficacy of a biweekly dosage formulation of exenatide in Zucker diabetic fatty (ZDF) ratsQ43276080
A long-acting formulation of a polypeptide drug exenatide in treatment of diabetes using an injectable block copolymer hydrogelQ43735089
Selectivity of LC-MS/MS analysis: implication for proteomics experiments.Q43864979
Recombination and functional studies of a dual-action peptide for diabetesQ44227850
Application of DBS for Quantitative Assessment of the Peptide Exendin-4; Comparison of Plasma and DBS Method by UHPLC–MS/MSQ45400105
Multilayer nanoparticles for sustained delivery of exenatide to treat type 2 diabetes mellitusQ45691518
Large-molecule quantification: sensitivity and selectivity head-to-head comparison of triple quadrupole with Q-TOF.Q46069949
Active phytochemicals of Pueraria tuberosa for DPP-IV inhibition: in silico and experimental approach.Q46339499
Effect of water on exenatide acylation in poly(lactide-co-glycolide) microspheresQ46562749
Stability of exenatide in poly(D,L-lactide-co-glycolide) solutions: a simplified investigation on the peptide degradation by the polymerQ47227494
Purification, identification and molecular mechanism of two dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from Antarctic krill (Euphausia superba) protein hydrolysateQ47670208
Minimizing target interference in PK immunoassays: new approaches for low-pH-sample treatmentQ47884443
Dipeptidyl peptidase-IV inhibitory peptides generated by tryptic hydrolysis of a whey protein concentrate rich in β-lactoglobulin.Q50887910
In vivo imaging of the glucagonlike peptide 1 receptor in the pancreas with 68Ga-labeled DO3A-exendin-4.Q50912475
Multiplexed Quantification of Proglucagon-Derived Peptides by Immunoaffinity Enrichment and Tandem Mass Spectrometry after a Meal Tolerance Test.Q50928547
DURATION-5: exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes.Q51379684
Tf ligand-receptor-mediated exenatide-Zn2+ complex oral-delivery system for penetration enhancement of exenatide.Q52331353
A review of analytical procedures for the simultaneous determination of medically important veterinary antibiotics in environmental water: Sample preparation, liquid chromatography, and mass spectrometry.Q52591543
Mechanistic studies for monodisperse exenatide-loaded PLGA microspheres prepared by different methods based on SPG membrane emulsification.Q53520319
Purification, identification and structural modelling of DPP-IV inhibiting peptides from barbel protein hydrolysate.Q53779614
Type 2 diabetes mellitusQ58447602
Comparison of triple quadrupole and high-resolution TOF-MS for quantification of peptidesQ61971658
Enhancing Stability of Exenatide-Containing Pressurized Metered-Dose Inhaler Via Reverse Microemulsion System.Q64892504
Evidence for presence of IgG4 anti-immunoglobulin autoantibodies in all human beingsQ73814611
Pathology: Cause and effectQ74440795
Impact of GHBP interference on estimates of GH and GH pharmacokineticsQ78596759
Human heterophilic antibodies display specificity for murine IgG subclassesQ81633049
Bioanalytical strategies for developing highly sensitive liquid chromatography/tandem mass spectrometry based methods for the peptide GLP-1 agonists in support of discovery PK/PD studiesQ82045686
Application of novel peptide (Pp1) improving the half-life of exendin-4 in vivoQ83445268
Combination of ELISA and dried blood spot technique for the quantification of large molecules using exenatide as a modelQ83940517
Peptide complex containing GLP-1 exhibited long-acting properties in the treatment of type 2 diabetesQ84273969
Combined use of immunoassay and two-dimensional liquid chromatography mass spectrometry for the detection and identification of metabolites from biotherapeutic pharmacokinetic samplesQ84402539
Intravitreal Injection of Exendin-4 Analogue Protects Retinal Cells in Early Diabetic RatsQ84676969
Development of a fast method for direct analysis of intact synthetic insulins in human plasma: the large peptide challengeQ85750599
Preparation of uniform-sized exenatide-loaded PLGA microspheres as long-effective release system with high encapsulation efficiency and bio-stabilityQ86055776
In vitro and in vivo evaluation of a once-weekly formulation of an antidiabetic peptide drug exenatide in an injectable thermogelQ86506211
Development and validation of a multi-residue screening method for veterinary drugs, their metabolites and pesticides in meat using liquid chromatography-tandem mass spectrometryQ86621984
Acylation of exenatide by glycolic acid and its anti-diabetic activities in db/db miceQ87320247
P433issue3
P921main subjectliquid chromatography–mass spectrometryQ873864
P304page(s)143-155
P577publication date2019-02-26
P1433published inJournal of Pharmaceutical AnalysisQ27725801
P1476titleComparison of ELISA and HPLC-MS methods for the determination of exenatide in biological and biotechnology-based formulation matrices
P478volume9

Search more.