LdrB Toxin with In Vitro and In Vivo Antitumor Activity as a Potential Tool for Cancer Gene Therapy

scientific article published on 20 July 2019

LdrB Toxin with In Vitro and In Vivo Antitumor Activity as a Potential Tool for Cancer Gene Therapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/CANCERS11071016
P932PMC publication ID6678987
P698PubMed publication ID31330822

P50authorHouria Boulaiz TassiQ75954051
Carmen Griñán-LisónQ91282581
Juan Antonio MarchalQ37370058
P2093author name stringAna Martín
Gema Jiménez
Alba Cambrils
Andrea Ibáñez Grau
Hoda Khaldy
Yaiza Jiménez-Martínez
P2860cites workRASTA-Bacteria: a web-based tool for identifying toxin-antitoxin loci in prokaryotesQ21184115
Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cellsQ24630262
Mechanisms of drug resistance in colon cancer and its therapeutic strategiesQ26738528
Viral vectors: a look back and ahead on gene transfer technologyQ26823087
Toxin-based therapeutic approachesQ27013664
Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrestQ28206549
Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system.Q50499408
Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins.Q54203079
4-Acetyl-Antroquinonol B Suppresses SOD2-Enhanced Cancer Stem Cell-Like Phenotypes and Chemoresistance of Colorectal Cancer Cells by Inducing hsa-miR-324 re-ExpressionQ58789473
Drug development: Mix and matchQ59098616
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countriesQ60142201
Activation of the PERK-ATF4 pathway promotes chemo-resistance in colon cancer cellsQ64084778
Deciphering the Mechanism of Action Involved in Enhanced Suicide Gene Colon Cancer Cell Killer Effect Mediated by Gef and ApoptinQ64108076
Enhancement of Tumor Cell Death by Combining gef Gene Mediated Therapy and New 1,4-Benzoxazepin-2,6-Dichloropurine Derivatives in Breast Cancer CellsQ90860426
Turmeric extract, with absorbable curcumin, has potent anti-metastatic effect in vitro and in vivoQ90876771
GLOBOCAN 2018: counting the toll of cancerQ91841430
Molecular characterization of long direct repeat (LDR) sequences expressing a stable mRNA encoding for a 35-amino-acid cell-killing peptide and a cis-encoded small antisense RNA in Escherichia coliQ28214985
Progress and problems with the use of suicide genes for targeted cancer therapyQ28262370
Improved Tet-responsive promoters with minimized background expressionQ33755382
Divergently overlapping cis-encoded antisense RNA regulating toxin-antitoxin systems from E. coli: hok/sok, ldr/rdl, symE/symR.Q34310279
gef gene expression in MCF-7 breast cancer cells is associated with a better prognosis and induction of apoptosis by p53-mediated signaling pathwayQ35600102
Gene therapy for cancer: present status and future perspectiveQ35673900
Specific Colon Cancer Cell Cytotoxicity Induced by Bacteriophage E Gene Expression under Transcriptional Control of Carcinoembryonic Antigen Promoter.Q35813896
Apoptosis and colorectal cancerQ35915905
Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapyQ36279105
Broad targeting of resistance to apoptosis in cancer.Q36483749
Diphtheria toxin-epidermal growth factor fusion protein DAB389EGF for the treatment of bladder cancerQ36511054
Frontiers in Suicide Gene Therapy of CancerQ36534930
Inhibition of growth and induction of apoptosis in human breast cancer by transfection of gef gene.Q36670856
Tumor resistance to apoptosisQ37323744
Bacteria in cancer therapy: a novel experimental strategyQ37717794
Effectiveness and preclinical safety profile of doxycycline to be used "off-label" to induce therapeutic transgene expression in a phase I clinical trial for gliomaQ37730116
Regulation of growth and death in Escherichia coli by toxin-antitoxin systems.Q37934486
Mechanisms of Apoptin-induced cell deathQ37959247
3D cell culture systems: advantages and applicationsQ38218818
3D tumor models: history, advances and future perspectivesQ38221694
In vitro and in vivo anticancer activity of posterior salivary gland toxin from the cuttlefish Sepia pharaonis, Ehrenberg (1831).Q38687012
Cancer suicide gene therapy: a patent review.Q38841046
Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancerQ38915097
Bacterial Toxins for Oncoleaking Suicidal Cancer Gene TherapyQ39094451
A novel double-enhanced suicide gene therapy in a colon cancer cell line mediated by gef and apoptinQ39114380
LukS-PV induces mitochondrial-mediated apoptosis and G0/G1 cell cycle arrest in human acute myeloid leukemia THP-1 cellsQ39148218
Clinical experience of treatment of metastatic melanoma and solid tumours adopting a derivative of diphtheria toxin: cross-reacting material 197.Q40256912
A transgenic mouse model with inducible Tyrosinase gene expression using the tetracycline (Tet-on) system allows regulated rescue of abnormal chiasmatic projections found in albinismQ44976090
Transfection of MS-36 melanoma cells with gef gene inhibits proliferation and induces modulation of the cell cycleQ45863122
Cancer gene therapy by thyroid hormone-mediated expression of toxin genesQ45868843
Characterization of LdrA (long direct repeat A) protein of Escherichia coliQ48354309
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue7
P921main subjectcancer gene therapyQ124350675
P577publication date2019-07-20
P1433published inCancersQ27722963
P1476titleLdrB Toxin with In Vitro and In Vivo Antitumor Activity as a Potential Tool for Cancer Gene Therapy
P478volume11

Search more.