Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth

scientific article published on 21 May 2019

Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.201805044
P932PMC publication ID6605806
P698PubMed publication ID31113824

P50authorDaniel W GerlichQ47502471
Gaudenz DanuserQ60658035
Philippe RoudotQ85396352
Ana Filipa DavidQ87401454
P2093author name stringEric Betzig
Wesley R Legant
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HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrityQ24308769
The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cellsQ24316058
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EB1 targets to kinetochores with attached, polymerizing microtubulesQ24541553
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Regional variation of microtubule flux reveals microtubule organization in the metaphase meiotic spindleQ30483135
Spindle assembly in the absence of a RanGTP gradient requires localized CPC activityQ30490581
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Augmin-dependent microtubule nucleation at microtubule walls in the spindleQ30541252
Force- and length-dependent catastrophe activities explain interphase microtubule organization in fission yeast.Q42272842
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Causes and Consequences of Microtubule AcetylationQ50064987
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A Force-Induced Directional Switch of a Molecular Motor Enables Parallel Microtubule Bundle Formation.Q51418544
The ran GTPase regulates mitotic spindle assembly.Q52535025
Drosophila Dgt6 interacts with Ndc80, Msps/XMAP215, and gamma-tubulin to promote kinetochore-driven MT formation.Q52699511
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Molecular recognition of taxol by microtubules. Kinetics and thermodynamics of binding of fluorescent taxol derivatives to an exposed siteQ73807679
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Nucleation and transport organize microtubules in metaphase spindles.Q34249898
Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.Q34328106
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Reconstitution of the augmin complex provides insights into its architecture and function.Q34575205
Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extractsQ35198046
Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulinQ35584145
The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle.Q35668564
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Katanin controls mitotic and meiotic spindle lengthQ36119429
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Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts.Q36531791
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FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindleQ36993384
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Advances in analysis of low signal-to-noise images link dynamin and AP2 to the functions of an endocytic checkpointQ37612060
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Acentrosomal Microtubule Assembly in Mitosis: The Where, When, and How.Q38609573
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P433issue7
P1104number of pages19
P304page(s)2150-2168
P577publication date2019-05-21
P1433published inJournal of Cell BiologyQ1524550
P1476titleAugmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth
P478volume218

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cites work (P2860)
Q83224534Biochemical reconstitution of branching microtubule nucleation
Q92152613Direct observation of branching MT nucleation in living animal cells
Q92344236How Does SUMO Participate in Spindle Organization?
Q83224512In vitro reconstitution of branching microtubule nucleation
Q93160968Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner

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