Characterisation of the Ral GTPase inhibitor RBC8 in human and mouse platelets

scientific article published on 14 March 2019

Characterisation of the Ral GTPase inhibitor RBC8 in human and mouse platelets is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELLSIG.2019.03.015
P932PMC publication ID6510928
P698PubMed publication ID30880223

P50authorTony G WalshQ88078231
P2093author name stringAlastair W Poole
Andreas Wersäll
P2860cites workRas activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase CQ24318637
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Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesisQ28507796
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RalA but not RalB enhances polarized delivery of membrane proteins to the basolateral surface of epithelial cellsQ30449192
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Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladderQ33630889
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RhoG protein regulates platelet granule secretion and thrombus formation in mice.Q37333850
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SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4.Q42170536
Copy number analysis of the murine platelet proteome spanning the complete abundance rangeQ42209721
Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets.Q42564153
RGD-ligand mimetic antagonists of integrin alphaIIbbeta3 paradoxically enhance GPVI-induced human platelet activation.Q43225359
Thrombin-induced activation of RhoA in platelet shape change.Q43732014
Platelet ADP receptors contribute to the initiation of intravascular coagulationQ44582240
CalDAG-GEFI is at the nexus of calcium-dependent platelet activation.Q45921416
The RalA GTPase is a central regulator of insulin exocytosis from pancreatic islet beta cells.Q46082494
Rac1 is essential for phospholipase C-gamma2 activation in plateletsQ46428451
Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathwayQ46949445
Procoagulant platelets: generation, function, and therapeutic targeting in thrombosisQ47859594
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Mouse Platelet Ral GTPases Control P-Selectin Surface Expression, Regulating Platelet-Leukocyte Interaction.Q50044452
Measuring and interpreting platelet-leukocyte aggregates.Q54270261
Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets.Q55068394
Small GTPases in platelet membrane traffickingQ58549008
Loss of the mitochondrial kinase PINK1 does not alter platelet functionQ58695524
Small GTP-binding protein RalA associates with Weibel-Palade bodies in endothelial cellsQ73013586
Dysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemiaQ85657160
P1104number of pages7
P304page(s)34-40
P577publication date2019-03-14
P1433published inCellular SignallingQ1524097
P1476titleCharacterisation of the Ral GTPase inhibitor RBC8 in human and mouse platelets
P478volume59

Reverse relations

Q90638601RAL GTPases mediate multiple myeloma cell survival and are activated independently of oncogenic RAScites workP2860

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