| scholarly article | Q13442814 |
| P2093 | author name string | Byoung Dae Lee | |
| Eun-Mi Hur | |||
| Eun-Hae Jang | |||
| Ga Ram Jeong | |||
| P2860 | cites work | A deleterious mutation in DNAJC6 encoding the neuronal-specific clathrin-uncoating co-chaperone auxilin, is associated with juvenile parkinsonism | Q21560999 |
| Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity | Q22254785 | ||
| LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool | Q24292798 | ||
| Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease | Q24294458 | ||
| LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis | Q24299176 | ||
| LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1 | Q24301357 | ||
| Kinase activity of mutant LRRK2 mediates neuronal toxicity | Q24303603 | ||
| LRRK2 transport is regulated by its novel interacting partner Rab32 | Q24306357 | ||
| RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk | Q24315688 | ||
| LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25 | Q24317760 | ||
| Localization of LRRK2 to membranous and vesicular structures in mammalian brain | Q24318643 | ||
| Interplay of LRRK2 with chaperone-mediated autophagy | Q24322747 | ||
| Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease | Q24336432 | ||
| LRRK2 regulates synaptic vesicle endocytosis | Q24336523 | ||
| Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity | Q24338647 | ||
| Mechanism of endophilin N-BAR domain-mediated membrane curvature | Q24550828 | ||
| Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms | Q24550829 | ||
| Genome-wide association study reveals genetic risk underlying Parkinson's disease | Q24646654 | ||
| LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model | Q24656256 | ||
| Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models | Q24683059 | ||
| Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP | Q27765278 | ||
| Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases | Q28119192 | ||
| Rab GTPases as coordinators of vesicle traffic | Q28131746 | ||
| Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology | Q28131833 | ||
| Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating | Q28184962 | ||
| Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease | Q28244731 | ||
| Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease | Q28292932 | ||
| Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission | Q28505115 | ||
| Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice | Q28507051 | ||
| Role of Rab GTPases in membrane traffic and cell physiology | Q29616548 | ||
| Kinase activity is required for the toxic effects of mutant LRRK2/dardarin | Q29620478 | ||
| Endophilin functions as a membrane-bending molecule and is delivered to endocytic zones by exocytosis. | Q30155977 | ||
| The role of dynamin and its binding partners in coated pit invagination and scission | Q30168371 | ||
| An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family. | Q30350674 | ||
| Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis | Q33595218 | ||
| Endophilin A1 induces different membrane shapes using a conformational switch that is regulated by phosphorylation | Q33627399 | ||
| Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease | Q34112588 | ||
| Coordinate Regulation of Neurite Outgrowth by LRRK2 and Its Interactor, Rab5. | Q35545939 | ||
| The role of Snapin in neurosecretion: snapin knock-out mice exhibit impaired calcium-dependent exocytosis of large dense-core vesicles in chromaffin cells | Q35647623 | ||
| Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning | Q35771011 | ||
| The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease | Q36325701 | ||
| The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis | Q36423369 | ||
| α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models | Q36607556 | ||
| LRRK2: Cause, Risk, and Mechanism | Q37635000 | ||
| LRRK2 G2019S in the North African population: a review | Q37736205 | ||
| Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease | Q38009436 | ||
| Synaptic vesicle endocytosis | Q38024048 | ||
| Alterations in late endocytic trafficking related to the pathobiology of LRRK2-linked Parkinson's disease | Q38502057 | ||
| Review: Progresses in understanding N-ethylmaleimide sensitive factor (NSF) mediated disassembly of SNARE complexes | Q38803266 | ||
| Defects in trafficking bridge Parkinson's disease pathology and genetics | Q39004335 | ||
| G2019S LRRK2 mutation in French and North African families with Parkinson's disease | Q39171895 | ||
| Computational analysis of the LRRK2 interactome | Q41301744 | ||
| LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate | Q42288293 | ||
| A dopaminergic axon lattice in the striatum and its relationship with cortical and thalamic terminals. | Q42443999 | ||
| Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice. | Q44852323 | ||
| DNAJC6 is responsible for juvenile parkinsonism with phenotypic variability. | Q45493890 | ||
| Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum. | Q46162532 | ||
| Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. | Q47142767 | ||
| Rab29 activation of the Parkinson's disease-associated LRRK2 kinase | Q47150726 | ||
| LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network | Q47362838 | ||
| Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease | Q48450468 | ||
| Disease penetrance of late-onset parkinsonism: a meta-analysis | Q48480120 | ||
| LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity. | Q48627154 | ||
| Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration | Q50032438 | ||
| Fine mapping and resequencing of the PARK16 locus in Parkinson's disease | Q54279109 | ||
| LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis | Q58745072 | ||
| LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson's disease | Q64875475 | ||
| Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes | Q93001087 | ||
| P433 | issue | 9 | |
| P921 | main subject | Parkinson's disease | Q11085 |
| P304 | page(s) | 533-539 | |
| P577 | publication date | 2019-09-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | BMB Reports | Q15764027 |
| P1476 | title | LRRK2 and membrane trafficking: nexus of Parkinson's disease | |
| P478 | volume | 52 |
| Q89611946 | Advances in elucidating the function of leucine-rich repeat protein kinase-2 in normal cells and Parkinson's disease | cites work | P2860 |
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