Matrix Metalloproteases as Influencers of the Cells' Social Media

scientific article published on 07 August 2019

Matrix Metalloproteases as Influencers of the Cells' Social Media is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/IJMS20163847
P932PMC publication ID6720954
P698PubMed publication ID31394726

P50authorAntoine DufourQ91487804
P2093author name stringDaniel Young
Nabangshu Das
Anthonia Anowai
P2860cites workDifferential roles of CXCL2 and CXCL3 and their receptors in regulating normal and asthmatic airway smooth muscle cell migrationQ41913259
Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand siteQ42177034
The first MMP in sepsisQ42233338
Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsionQ42264802
ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic siteQ42382724
EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion.Q42795950
Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors.Q42818095
Biochemical and pharmacological criteria define two shedding activities for TRANCE/OPGL that are distinct from the tumor necrosis factor alpha convertaseQ43559838
An alternative processing of integrin alpha(v) subunit in tumor cells by membrane type-1 matrix metalloproteinaseQ43821714
Proteolysis of latent transforming growth factor-beta (TGF-beta )-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix.Q43945272
Oxidized low-density lipoproteins stimulate extracellular matrix metalloproteinase Inducer (EMMPRIN) release by coronary smooth muscle cellsQ45023433
Endothelial nitric oxide deficiency reduces MMP-13-mediated cleavage of ICAM-1 in vascular endothelium: a role in atherosclerosis.Q46260965
Pervanadate-induced shedding of the intercellular adhesion molecule (ICAM)-1 ectodomain is mediated by membrane type-1 matrix metalloproteinase (MT1-MMP).Q46613828
Trends in GPCR drug discovery: new agents, targets and indications.Q47597808
Cleavage of CD95 by matrix metalloproteinase-7 induces apoptosis resistance in tumour cellsQ47784861
Gelatinase B/matrix metalloproteinase-9 cleaves interferon-beta and is a target for immunotherapyQ47891881
Structure and dynamics of GPCR signaling complexes.Q50093625
Ablation of matrix metalloproteinase-9 increases severity of viral myocarditis in mice.Q50656639
A role for CCR9 in T lymphocyte development and migration.Q52545510
The mechanically activated p38/MMP-2 signaling pathway promotes bone marrow mesenchymal stem cell migration in rats.Q52798190
Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease.Q53319618
Proteomics discovery of metalloproteinase substrates in the cellular context by iTRAQ labeling reveals a diverse MMP-2 substrate degradome.Q53579885
MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL.Q53856850
Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity.Q54019102
C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.Q55382749
Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion.Q55474490
Role of Metalloproteases in the Release of the IL-1 type II Decoy ReceptorQ56943427
How do cytotoxic lymphocytes kill their targets?Q57720900
Processing of tumour necrosis factor-α precursor by metalloproteinasesQ59059630
Authentic matrix vesicles contain active metalloproteases (MMP). a role for matrix vesicle-associated MMP-13 in activation of transforming growth factor-betaQ73366344
Increased soluble interleukin-1 receptor type II proteolysis in the endometrium of women with endometriosisQ81390737
The matrix metalloproteinase stromelysin-3 cleaves laminin receptor at two distinct sites between the transmembrane domain and laminin binding sequence within the extracellular domainQ81550469
MT1-MMP modulates the mechanosensitivity of osteocytesQ83143442
Autoimmunity: Interferon α or β: which is the culprit in autoimmune disease?Q87891417
Cytokine-mediated communication: a quantitative appraisal of immune complexityQ91637367
Degradomics of matrix metalloproteinases in inflammatory diseasesQ95816218
Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathwaysQ22009006
Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoformsQ22009107
APP binds DR6 to trigger axon pruning and neuron death via distinct caspasesQ22251088
Hallmarks of Cancer: The Next GenerationQ22252312
Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2BQ24312103
Functional analysis of the posttranslational modifications of the death receptor 6Q24321317
Enzymatic processing of beta-dystroglycan recombinant ectodomain by MMP-9: identification of the main cleavage siteQ24323201
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesisQ24610450
An overview of the intrathymic intricacies of T cell developmentQ26862512
Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potentialQ27676429
CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating CellsQ28084610
Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3Q28144040
Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymusQ28204211
The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPsQ28215674
Metalloproteases cleave the urokinase-type plasminogen activator receptor in the D1-D2 linker region and expose epitopes not present in the intact soluble receptorQ28219045
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytesQ28237565
CD44 is the principal cell surface receptor for hyaluronateQ28261336
The ephrins and Eph receptors in neural developmentQ28266706
Eph/ephrin signalling during developmentQ28277802
Identification and functional characterization of DR6, a novel death domain-containing TNF receptorQ28280342
Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influxQ28288712
The role of MMP7 and its cross-talk with the FAS/FASL system during the acquisition of chemoresistance to oxaliplatinQ28474925
The first stage of transforming growth factor beta1 activation is release of the large latent complex from the extracellular matrix of growth plate chondrocytes by matrix vesicle stromelysin-1 (MMP-3)Q28565188
Degradation of decorin by matrix metalloproteinases: identification of the cleavage sites, kinetic analyses and transforming growth factor-beta1 releaseQ28611028
Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinasesQ28611036
A new transcriptional role for matrix metalloproteinase-12 in antiviral immunityQ28910180
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2Q29622852
Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomicsQ30387118
Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1.Q37486259
Proteomic identification of multitasking proteins in unexpected locations complicates drug targetingQ37641731
Intracellular substrate cleavage: a novel dimension in the biochemistry, biology and pathology of matrix metalloproteinases.Q37784801
Mechanisms of T cell development and transformation.Q37899181
Metalloproteinases and their natural inhibitors in inflammation and immunity.Q38130854
Chemokines and chemokine receptors: positioning cells for host defense and immunityQ38198156
Is there new hope for therapeutic matrix metalloproteinase inhibition?Q38265674
GPCR Dynamics: Structures in MotionQ38953232
CD44: More than a mere stem cell marker.Q38957873
Extracellular Matrix Proteolysis by MT1-MMP Contributes to Influenza-Related Tissue Damage and Mortality.Q39298374
Biochemical analysis of matrix metalloproteinase activation of chemokines CCL15 and CCL23 and increased glycosaminoglycan binding of CCL16.Q39432022
Matrilysin (MMP-7) cleaves C-type lectin domain family 3 member A (CLEC3A) on tumor cell surface and modulates its cell adhesion activityQ39890288
Tumor necrosis factor receptor superfamily member 21: TNFR-related death receptor-6, DR6.Q39946611
Role of the hemopexin domain of matrix metalloproteinases in cell migrationQ39959867
Tumor-derived death receptor 6 modulates dendritic cell developmentQ40061758
Membrane-type 1-matrix metalloproteinase regulates intracellular adhesion molecule-1 (ICAM-1)-mediated monocyte transmigrationQ40115388
Caspase-1-dependent processing of pro-interleukin-1beta is cytosolic and precedes cell deathQ40173865
Proteolytic activation of alternative CCR1 ligands in inflammationQ40419745
PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.Q40459317
Cell-surface-associated tissue transglutaminase is a target of MMP-2 proteolysisQ40516467
Tumor-stroma interaction: positive feedback regulation of extracellular matrix metalloproteinase inducer (EMMPRIN) expression and matrix metalloproteinase-dependent generation of soluble EMMPRIN.Q40585451
Constitutive and induced CD44 shedding by ADAM-like proteases and membrane-type 1 matrix metalloproteinase.Q40590824
Matrix metalloproteinase-dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosisQ40704627
Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivoQ40714466
Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorptionQ40716553
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migrationQ40802553
Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing.Q41005189
Macrophage metalloelastase degrades matrix and myelin proteins and processes a tumour necrosis factor-alpha fusion proteinQ41151470
Degradation of interleukin 1beta by matrix metalloproteinases.Q41190792
CD44: structure, function, and association with the malignant process.Q41438683
Cytokines and signaling pathways regulating matrix metalloproteinase-9 (MMP-9) expression in corneal epithelial cellsQ41558819
Regulation of Chemokine Function: The Roles of GAG-Binding and Post-Translational NitrationQ41573564
Furin Functions as a Nonproteolytic Chaperone for Matrix Metalloproteinase-28: MMP-28 Propeptide Sequence RequirementQ41679116
Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1-matrix metalloproteinase substratesQ33202468
Cleavage of amyloid-beta precursor protein (APP) by membrane-type matrix metalloproteinasesQ33237788
Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situQ33247376
MMP-9 sheds the beta2 integrin subunit (CD18) from macrophagesQ33396615
Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2.Q33900860
CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrowQ33968069
Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophage phagocytic activitiesQ34172720
Tumor necrosis factor signaling.Q34185821
Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities.Q34226948
Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsionQ34230386
Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptidesQ34285372
Does CD95 have tumor promoting activities?Q34557850
MT1-MMP controls tumor-induced angiogenesis through the release of semaphorin 4D.Q34598008
Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammationQ34665150
Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.Q34942166
Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9Q35112695
Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration.Q35313033
Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapyQ35474102
ProMMP-2: TIMP-1 complexes identified in plasma of healthy individualsQ35778090
Protease-activated receptors (PARs)--biology and role in cancer invasion and metastasis.Q36322931
Metalloproteinase-mediated release of human Fas ligandQ36365559
Fas/CD95 death receptor and lipid rafts: new targets for apoptosis-directed cancer therapy.Q36474432
Cleavage of myelin associated glycoprotein by matrix metalloproteinasesQ36513220
Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosisQ36518598
Matrix metalloproteases and PAR1 activationQ36542806
Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I.Q36629274
IL-1β promotes corneal epithelial cell migration by increasing MMP-9 expression through NF-κB- and AP-1-dependent pathwaysQ36665694
Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases.Q36836612
MMP-7 cleaves the NR1 NMDA receptor subunit and modifies NMDA receptor functionQ36950980
Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.Q37040818
Relationships between glycosaminoglycan and receptor binding sites in chemokines-the CXCL12 example.Q37107623
Metalloproteinase- and gamma-secretase-mediated cleavage of protein-tyrosine phosphatase receptor type ZQ37142719
Proteinase-activated receptors (PARs) - focus on receptor-receptor-interactions and their physiological and pathophysiological impactQ37348262
Matrix metalloproteinases as drug targets in infections caused by gram-negative bacteria and in septic shockQ37444400
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue16
P921main subjectsocial mediaQ202833
P577publication date2019-08-07
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleMatrix Metalloproteases as Influencers of the Cells' Social Media
P478volume20

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cites work (P2860)
Q91646232Intracellular Localization in Zebrafish Muscle and Conserved Sequence Features Suggest Roles for Gelatinase A Moonlighting in Sarcomere Maintenance
Q89550740Matrix Metalloproteinase 13 Activity is Required for Normal and Hypoxia-Induced Precocious Hatching in Zebrafish Embryos
Q89660177Matrix Metalloproteinases in Diabetic Kidney Disease
Q98159046Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8
Q99571028The Role of Extracellular Proteases in Tumor Progression and the Development of Innovative Metal Ion Chelators that Inhibit their Activity
Q98227874The matrix metalloproteinase 7 (MMP7) links Hsp90 chaperone with acquired drug resistance and tumor metastasis

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