The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth

scientific article published on 13 August 2019

The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41418-019-0402-X
P932PMC publication ID7206145
P698PubMed publication ID31406304

P2093author name stringYing Ma
Dongping Wei
Yongchao Zhao
Danrui Cui
Xiufang Xiong
Jianfeng Shu
Xiaoqing Dai
P2860cites workRotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonismQ21090517
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)Q24293710
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survivalQ24311448
AMPK phosphorylation of raptor mediates a metabolic checkpointQ24329244
Regulation of mTOR and cell growth in response to energy stress by REDD1.Q24531971
Systematic analysis and nomenclature of mammalian F-box proteinsQ24561715
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerQ24648025
Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-UQ24672630
Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttlingQ24677061
Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitinationQ27645983
RING domain E3 ubiquitin ligasesQ27860546
Multiple isoforms of beta-TrCP display differential activities in the regulation of Wnt signalingQ28119010
Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitinationQ28143145
Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivoQ28177348
mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTORQ28251026
DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagyQ28251037
mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTORQ28251047
REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligaseQ28390295
Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 geneQ28506095
Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 ComplexQ28554481
SAG/RBX2 E3 ligase complexes with UBCH10 and UBE2S E2s to ubiquitylate β-TrCP1 via K11-linkage for degradationQ28818138
Methods in mammalian autophagy researchQ29547276
Autophagy and the Integrated Stress ResponseQ29547398
mTOR regulation of autophagyQ29616301
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancerQ29616732
The LKB1-AMPK pathway: metabolism and growth control in tumour suppressionQ29617506
Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axisQ30525356
Roles of F-box proteins in cancerQ35012352
The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancerQ35691542
Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 LigaseQ35912398
The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesisQ36029051
S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell ProliferationQ36070012
Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomeraseQ36074577
Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancerQ37002726
The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressorQ37591349
The cullin protein familyQ37873586
Cullin-RING Ligases as attractive anti-cancer targetsQ38059746
AMPK: An Energy-Sensing Pathway with Multiple Inputs and OutputsQ38652124
Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-κB and β-catenin/TCF signaling pathways.Q52349771
Threonine 41 in beta-catenin serves as a key phosphorylation relay residue in beta-catenin degradationQ83160998
SCFβ-TrCP ubiquitinates CHK1 in an AMPK-dependent manner in response to glucose deprivationQ93073348
P433issue3
P921main subjectautophagyQ288322
P304page(s)1119-1133
P577publication date2019-08-13
P1433published inCell Death & DifferentiationQ2943974
P1476titleThe cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth
P478volume27

Reverse relations

cites work (P2860)
Q102053801DEPTOR is a direct p53 target that suppresses cell growth and chemosensitivity
Q90746433F-box proteins and cancer: an update from functional and regulatory mechanism to therapeutic clinical prospects
Q89518280SCFβ-TrCP-mediated degradation of TOP2β promotes cancer cell survival in response to chemotherapeutic drugs targeting topoisomerase II

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