Expression and prognostic role of IKBKE and TBK1 in stage I non-small cell lung cancer

scientific article published on 15 July 2019

Expression and prognostic role of IKBKE and TBK1 in stage I non-small cell lung cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/CMAR.S204924
P932PMC publication ID6642623
P698PubMed publication ID31406474

P2093author name stringXin Wang
Jinming Yu
Jie Lu
Jianbo Zhang
Dianbin Mu
Feifei Teng
P2860cites workRisk factors for tumor recurrence in patients with early-stage (stage I and II) non-small cell lung cancer: patient selection criteria for adjuvant chemotherapy according to the seventh edition TNM classification.Q53244493
PLK4 is a determinant of temozolomide sensitivity through phosphorylation of IKBKE in glioblastomaQ90356457
TANK-binding kinase 1 is a mediator of platelet-induced EMT in mammary carcinoma cellsQ92626368
IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinasesQ22010432
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinaseQ22010870
SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANKQ24310727
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivoQ24648140
Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signalingQ24679268
Molecular basis of Tank-binding kinase 1 activation by transautophosphorylationQ27679261
Crystal structure and mechanism of activation of TANK-binding kinase 1Q27684100
Cancer statistics, 2013Q27860762
NF-kappaB activation through IKK-i-dependent I-TRAF/TANK phosphorylationQ28141521
Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancerQ33988009
IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformationQ34215333
RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survivalQ34571216
Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF.Q34682122
Silencing of the IKKε gene by siRNA inhibits invasiveness and growth of breast cancer cellsQ34989052
Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammationQ34999011
Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic TargetsQ36116625
IκB Kinase ε expression in pancreatic ductal adenocarcinomaQ36280308
Identification of TBK1 and IKKε, the non-canonical IκB kinases, as crucial pro-survival factors in HTLV-1-transformed T lymphocytesQ36984362
Signaling to NF-kappaB by Toll-like receptorsQ37009320
Dissection of TBK1 signaling via phosphoproteomics in lung cancer cellsQ37049369
Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?Q37114307
Deregulation of IKBKE is associated with tumor progression, poor prognosis, and cisplatin resistance in ovarian cancerQ37257188
Prognostic and predictive markers of benefit from adjuvant chemotherapy in early-stage non-small cell lung cancer.Q37477973
Non-small-cell lung cancer: ESMO clinical recommendations for diagnosis, treatment and follow-upQ37489156
Selective TBK1/IKKi dual inhibitors with anticancer potencyQ37626577
IKKε and TBK1 expression in gastric cancerQ37725411
IκB kinase ε (IKKε): a therapeutic target in inflammation and cancerQ38075370
Personalized treatment of early-stage non-small-cell lung cancer: the challenging role of EGFR inhibitorsQ38400481
IKBKE is over-expressed in glioma and contributes to resistance of glioma cells to apoptosis via activating NF-κB.Q38413034
Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.Q38665092
mTOR Signaling in Growth, Metabolism, and Disease.Q38747508
IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex.Q39186578
Silencing of IKKε using siRNA inhibits proliferation and invasion of glioma cells in vitro and in vivoQ39354829
IKBKE regulates cell proliferation and epithelial-mesenchymal transition of human malignant glioma via the Hippo pathwayQ41472551
Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenanceQ41772814
Immunohistochemical analysis of NF-kappaB signaling proteins IKKepsilon, p50/p105, p52/p100 and RelA in prostate cancersQ42458122
IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancerQ42746137
The transient and constitutive inflammatory signaling in tumorigenesisQ42856220
Inducible IkappaB kinase/IkappaB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kappaB activation in breast cancer cellsQ46853168
The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonistsQ47576629
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P304page(s)6593-6602
P577publication date2019-07-15
P1433published inCancer Management and ResearchQ5031417
P1476titleExpression and prognostic role of IKBKE and TBK1 in stage I non-small cell lung cancer
P478volume11

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