Tumor microenvironment immune types in gastric cancer are associated with mismatch repair however, not HER2 status

scientific article published on 21 June 2019

Tumor microenvironment immune types in gastric cancer are associated with mismatch repair however, not HER2 status is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3892/OL.2019.10513
P932PMC publication ID6614673
P698PubMed publication ID31423245

P2093author name stringVito Guerra
Anna Maria Valentini
Maria Lucia Caruso
Federica Di Pinto
Raffaele Armentano
Sergio Coletta
P2860cites workPhase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.Q27824811
PD-L1 is an independent prognostic predictor in gastric cancer of Western patientsQ27853364
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Q27861047
Immune checkpoint blockade: a common denominator approach to cancer therapyQ28083981
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancerQ29616236
Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapyQ29617774
The two histological main types of gastric carcinoma: diffuse and so called intestinal-type carcinoma: an attempt at a histo-clinical classificationQ29618627
PD-1 blockade induces responses by inhibiting adaptive immune resistanceQ29620856
Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escapeQ29620881
Clinicopathologic implications of immune classification by PD-L1 expression and CD8-positive tumor-infiltrating lymphocytes in stage II and III gastric cancer patientsQ33688662
The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpointsQ34943776
The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapyQ34970884
Classifying Cancers Based on T-cell Infiltration and PD-L1.Q35674821
RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissuesQ35917676
Programmed cell death ligand 1 (PD-L1) expression on gastric cancer and its relationship with clinicopathologic factorsQ36261635
Targeted therapies in gastric cancer and future perspectives.Q36471685
Variability in Immunohistochemical Detection of Programmed Death Ligand 1 (PD-L1) in Cancer Tissue Types.Q36939402
Assessment of a HER2 scoring system for gastric cancer: results from a validation studyQ37142266
Gastric cancer pathology and underlying molecular mechanismsQ38122579
Is microsatellite instability a prognostic marker in gastric cancer? A systematic review with meta-analysis.Q38204955
Update on Epstein-Barr virus and gastric cancer (review).Q38336778
Role of PD-L1 expression as a biomarker for GEP neuroendocrine neoplasm grading.Q38610333
PD-L1 and gastric cancer prognosis: A systematic review and meta-analysis.Q38630412
Association between PD-L1 Expression on Tumour-Infiltrating Lymphocytes and Overall Survival in Patients with Gastric CancerQ38642012
PD-L1 expression is associated with massive lymphocyte infiltration and histology in gastric cancerQ38858292
Molecular and Biochemical Aspects of the PD-1 Checkpoint PathwayQ38996832
ImmunoScore Signature: A Prognostic and Predictive Tool in Gastric CancerQ39077848
Genomic landscape and genetic heterogeneity in gastric adenocarcinoma revealed by whole-genome sequencingQ39096557
HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and the American Society of Clinical Oncology.Q39106714
Safety and efficacy of nivolumab in the treatment of cancers: A meta-analysis of 27 prospective clinical trialsQ39215902
The therapeutic promise of disrupting the PD-1/PD-L1 immune checkpoint in cancer: unleashing the CD8 T cell mediated anti-tumor activity results in significant, unprecedented clinical efficacy in various solid tumorsQ39828989
Clinicopathological features of programmed death ligand 1 expression with tumor-infiltrating lymphocyte, mismatch repair, and Epstein-Barr virus status in a large cohort of gastric cancer patientsQ40581214
Immunohistochemistry as a surrogate for molecular subtyping of gastric adenocarcinomaQ40682693
Pan-Cancer Immunogenomic Perspective on the Tumor Microenvironment Based on PD-L1 and CD8 T-Cell InfiltrationQ40814909
A protein and mRNA expression-based classification of gastric cancerQ40824215
Clinicopathological analysis of programmed cell death 1 and programmed cell death ligand 1 expression in the tumour microenvironments of diffuse large B cell lymphomasQ40971062
Targeted therapies for gastric cancer: failures and hopes from clinical trialsQ41340207
Programmed cell death protein 1 expression is an independent prognostic factor in gastric cancer after curative resectionQ41547569
Combined prognostic effect of PD-L1 expression and immunoscore in microsatellite-unstable advanced gastric cancersQ41708934
Expression of Epstein-Barr virus genes and of lymphocyte activation molecules in undifferentiated nasopharyngeal carcinomasQ41809459
Differentiated tumor immune microenvironment of Epstein-Barr virus-associated and negative gastric cancer: implication in prognosis and immunotherapy.Q41924371
PD-1 and PD-L1 co-expression predicts favorable prognosis in gastric cancerQ41926342
Understanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistryQ42376660
Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanomaQ45054030
Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction.Q45851280
Predictive relevance of PD-L1 expression with pre-existing TILs in gastric cancerQ47137632
Tumor-associated macrophage infiltration is highly associated with PD-L1 expression in gastric adenocarcinoma.Q47728785
Protein Expression of Programmed Death 1 Ligand 1 and HER2 in Gastric Carcinoma.Q47802088
PD-L1 diagnostic tests: a systematic literature review of scoring algorithms and test-validation metricsQ49494082
Immunoclassification characterized by CD8 and PD-L1 expression is associated with the clinical outcome of gastric cancer patients.Q52649601
Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial.Q53837214
PD-L1 expression in colorectal cancer defines three subsets of tumor immune microenvironments.Q54935837
Programmed death-ligand 1 expression in gastric cancer: correlation with mismatch repair deficiency and HER2-negative status.Q55307728
Clinical Importance of Epstein⁻Barr Virus-Associated Gastric Cancer.Q55515323
IL-18 Induces PD-1-Dependent Immunosuppression in CancerQ57556330
New monoclonal antibodies against B-cell antigens: Possible new strategies for diagnosis of primary cutaneous B-cell lymphomasQ58482097
Anti-PD-1/PD-L1 Therapy for Non-Small-Cell Lung Cancer: Toward Personalized Medicine and Combination StrategiesQ58795231
Histologic grading of gastric cancerQ70410675
PD-1: an inhibitory immunoreceptor involved in peripheral toleranceQ73807451
Tissue processing and hematoxylin and eosin stainingQ87387123
Clinical Utility of the Combined Positive Score for Programmed Death Ligand-1 Expression and the Approval of Pembrolizumab for Treatment of Gastric CancerQ90360938
FDA Approval Summary: Pembrolizumab for Recurrent Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing PD-L1Q91011455
P433issue2
P921main subjectDNA mismatch repairQ2984243
P304page(s)1775-1785
P577publication date2019-06-21
P1433published inOncology LettersQ20640514
P1476titleTumor microenvironment immune types in gastric cancer are associated with mismatch repair however, not HER2 status
P478volume18

Search more.