Frank van de Veerdonk

researcher (ORCID 0000-0002-1121-4894)

Frank van de Veerdonk is …
instance of (P31):
humanQ5

External links are
P269IdRef ID243687346
P496ORCID iD0000-0002-1121-4894
P1053ResearcherIDC-7256-2008
P214VIAF ID1817159234135303370868

P735given nameFrankQ220546
FrankQ220546
P106occupationresearcherQ1650915
P5008on focus list of Wikimedia projectWikiProject COVID-19Q87748614
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q59334508967. Inhibition of Host Neuraminidase Increases Susceptibility to Invasive Pulmonary Aspergillosis
Q40463693A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.
Q93042542A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans
Q40128384A guiding map for inflammation
Q28540595A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist
Q92689765A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis
Q40834677An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism
Q97678142An exaggerated monocyte-derived cytokine response to Candida hyphae in patients with recurrent vulvovaginal candidiasis
Q38654393An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility
Q104278080Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study
Q43225292Anti-Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity.
Q38295131Antifungal innate immunity: recognition and inflammatory networks
Q40838979Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity
Q41997165Aspergillus fumigatus morphology and dynamic host interactions
Q44947091Aspergillus fumigatus-induced IL-22 is not restricted to a specific Th cell subset and is dependent on complement receptor 3.
Q120345739Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes
Q38645577Autoimmune Regulator Deficiency Results in a Decrease in STAT1 Levels in Human Monocytes
Q35377891Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer
Q41863342Autophagy modulates Borrelia burgdorferi-induced production of interleukin-1β (IL-1β)
Q38741955Basic Genetics and Immunology of Candida Infections
Q34393127Biology of IL-36 cytokines and their role in disease
Q97589284Blocking IL-1 to prevent respiratory failure in COVID-19
Q37612411Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism
Q46680943Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent.
Q40765104Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
Q46119741Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans
Q40588827CBLB ubiquitin ligase: a major regulator of antifungal immunity
Q95614531COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients
Q42972455Candida albicans dampens host defense by downregulating IL-17 production.
Q37967076Candida albicans morphogenesis and host defence: discriminating invasion from colonization.
Q120499615Caspase-1, but not ASC or NLRP3 inflammasome components, mediates IL-1beta activation and antifungal defense in disseminated candidiasis
Q112298597Comparative host transcriptome in response to pathogenic fungi identifies common and species-specific transcriptional antifungal host response pathways
Q35668803Compartmentalized Cytokine Responses in Hidradenitis Suppurativa
Q37442775Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signaling
Q34057772Cytokine production assays reveal discriminatory immune defects in adults with recurrent infections and noninfectious inflammation
Q37865925Defects of pattern recognition: primary immunodeficiencies of the innate immune system
Q46905194Deficient Candida-specific T-helper 17 response during sepsis
Q42729335Deficient autophagy unravels the ROS paradox in chronic granulomatous disease
Q47556941Development of Endotoxin Tolerance Does Not Influence the Response to a Challenge with the Mucosal Live-Attenuated Influenza Vaccine in Humans In Vivo
Q47296348Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis.
Q37119939Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages
Q85092283Diversity: A Hallmark of Monocyte Society
Q112689993Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial
Q98900263Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial
Q28384291Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis
Q56942360Erratum: IL-1 family nomenclature
Q28728570Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis
Q94923225FAVORABLE ANAKINRA RESPONSES IN SEVERE COVID-19 PATIENTS WITH SECONDARY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Q40131074Flucloxacillin Results in Suboptimal Plasma Voriconazole Concentrations.
Q38976165Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC).
Q34341908Genetic susceptibility to Candida infections
Q119570977Genome-Wide Association Study Reveals CLEC7A and PROM1 as Potential Regulators of Paracoccidioides brasiliensis-Induction of Cytokine Production in Peripheral Blood Mononuclear Cells
Q39170824Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity
Q34523567Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype
Q37207462Host-microbe interactions: innate pattern recognition of fungal pathogens
Q40850228Human Neutrophils Use Different Mechanisms To Kill Aspergillus fumigatus Conidia and Hyphae: Evidence from Phagocyte Defects.
Q101136069Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease
Q34144622IL-1 family nomenclature
Q36690556IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis
Q37627905IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans
Q120499612IL-1-8 IL-1β and the development of Th17 responses
Q33535878IL-1beta processing in host defense: beyond the inflammasomes
Q28072571IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections
Q28544789IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis
Q35779110IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist
Q41660745IL1B and DEFB1 Polymorphisms Increase Susceptibility to Invasive Mold Infection After Solid-Organ Transplantation
Q103826980Immune defects in patients with pulmonary Mycobacterium abscessus disease without cystic fibrosis
Q38590007Immune defence against Candida fungal infections
Q37481373Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia.
Q40692540Immunologic defects in severe mucocutaneous HSV-2 infections: Response to IFN-γ therapy
Q40107600Immunotherapeutic approaches to treatment of fungal diseases.
Q38259013Immunotherapy: a potential adjunctive treatment for fungal infection
Q38803776In-host adaptation and acquired triazole resistance in Aspergillus fumigatus: a dilemma for clinical management
Q37844754Inflammasome activation and IL-1β and IL-18 processing during infection
Q35216914Inflammasome is a central player in the induction of obesity and insulin resistance
Q33872210Inflammasome-independent modulation of cytokine response by autophagy in human cells
Q38286016Inflammasome-independent regulation of IL-1-family cytokines
Q33782663Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis
Q30400852Influenza-Associated Aspergillosis in Critically Ill Patients.
Q35567246Inhibition of caspase-1 activation in Gram-negative sepsis and experimental endotoxemia
Q35131761Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series
Q96291810Invasive Aspergillus Tracheobronchitis Emerging as Highly Lethal Complication of Severe Influenza
Q93253714Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome
Q38835840LC3-associated phagocytosis: a crucial mechanism for antifungal host defence against Aspergillus fumigatus
Q83105970Low interleukin-17A production in response to fungal pathogens in patients with chronic granulomatous disease
Q50065334Metabolic Induction of Trained Immunity through the Mevalonate Pathway.
Q104518207Mimicking Behcet's disease: GM-CSF gain of function mutation in a family suffering from a Behcet's disease-like disorder marked by extreme pathergy
Q28082840Modulation of inflammation by autophagy: Consequences for human disease
Q112637942Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19
Q36907628Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.
Q43124577Mycobacterium tuberculosis induces IL-17A responses through TLR4 and dectin-1 and is critically dependent on endogenous IL-1.
Q43685729Neutrophil-mediated inhibition of proinflammatory cytokine responses
Q38121074New Insights in the Immunobiology of IL-1 Family Members
Q37763270Novel strategies for the prevention and treatment of Candida infections: the potential of immunotherapy
Q119571018Opposing Effects of Interleukin-36γ and Interleukin-38 on Trained Immunity
Q37780092Pathogenesis of invasive candidiasis
Q41054725Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra
Q38751066Personalized medicine in influenza: a bridge too far or the near future?
Q94569365Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity
Q97517273Primary immunodeficiencies in cytosolic pattern-recognition receptor pathways: Toward host-directed treatment strategies
Q38717292Progressive multifocal leukoencephalopathy in an immunocompetent patient
Q34851532Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37.
Q24624942Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease
Q42687677Receptor recognition of and immune intracellular pathways for Veillonella parvula lipopolysaccharide
Q101126059Reduced concentrations of the B cell cytokine Interleukin 38 are associated with cardiovascular disease risk in overweight subjects
Q39742832Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
Q96642114Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion
Q41996952Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis
Q47127905Risks of Ruxolitinib in STAT1 Gain-of-Function-Associated Severe Fungal Disease
Q44211471Role of TLR1 and TLR6 in the host defense against disseminated candidiasis
Q35671653Role of interleukin-23 (IL-23) receptor signaling for IL-17 responses in human Lyme disease
Q34110879STAT1 hyperphosphorylation and defective IL12R/IL23R signaling underlie defective immunity in autosomal dominant chronic mucocutaneous candidiasis
Q34196284STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis
Q90030526STAT3 phosphorylation mediates the stimulatory effects of interferon alpha on B cell differentiation and activation in SLE
Q98663508Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study
Q37815686Severe Candida spp. infections: new insights into natural immunity
Q33709446Skin microbiome imbalance in patients with STAT1/STAT3 defects impairs innate host defense responses
Q37803134T-cell Subsets and Antifungal Host Defenses
Q41301353TREML4 adds fuel to the TLR7 fire
Q30415829Th17 cytokine deficiency in patients with Aspergillus skull base osteomyelitis
Q37665895Th17 responses and host defense against microorganisms: an overview
Q119684385The BNT162b2 mRNA Vaccine Against SARS-CoV-2 Reprograms Both Adaptive and Innate Immune Responses
Q42830119The Candida Th17 response is dependent on mannan- and beta-glucan-induced prostaglandin E2.
Q24303676The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses
Q37374119The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections
Q36786137The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis
Q84417973The classical CD14⁺⁺ CD16⁻ monocytes, but not the patrolling CD14⁺ CD16⁺ monocytes, promote Th17 responses to Candida albicans
Q42385375The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans
Q34558300The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases.
Q46310614The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production
Q41993160The effects of signal transducer and activator of transcription three mutations on human platelets.
Q30234689The immunopathology of sepsis and potential therapeutic targets
Q37612479The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis.
Q38423391The interplay between inflammasome activation and antifungal host defense
Q46044007The macrophage mannose receptor induces IL-17 in response to Candida albicans.
Q35277785The potential impact of the pulmonary microbiome on immunopathogenesis of Aspergillus-related lung disease
Q38232426The role of interleukin-1 family members in the host defence against Aspergillus fumigatus
Q40047847Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics
Q95295198Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection
Q104135153Trained immunity, tolerance, priming and differentiation: distinct immunological processes
Q38830589Treatment options for chronic mucocutaneous candidiasis
Q42209674Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects.
Q40588833Understanding human immune function using the resources from the Human Functional Genomics Project
Q45141589Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway
Q35914364When the Fight against Fungi Goes Wrong
Q34481477mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

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