Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer׳s disease

scientific article published on 30 December 2018

Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer׳s disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.APSB.2018.12.010
P953full work available at URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543096
P932PMC publication ID6543096
P698PubMed publication ID31193846

P2093author name stringWei Lu
Peng Yang
Qian Guo
Xinguo Jiang
Qizhi Zhang
Xiaoyao Zheng
Kang Qian
Shuting Xu
Xiaoying Pang
Pengzhen Wang
Liuchang Wang
Jinxu Cao
Dongyu Sheng
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A focus on the synapse for neuroprotection in Alzheimer disease and other dementiasQ35914866
Postsynaptic degeneration as revealed by PSD-95 reduction occurs after advanced Aβ and tau pathology in transgenic mouse models of Alzheimer's diseaseQ36221062
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GM1-Modified Lipoprotein-like Nanoparticle: Multifunctional Nanoplatform for the Combination Therapy of Alzheimer's Disease.Q40462766
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Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice.Q47707395
Shuttle-mediated nanoparticle delivery to the blood-brain barrierQ48304144
Impaired spatial learning in the APPSwe + PSEN1DeltaE9 bigenic mouse model of Alzheimer's disease.Q48306292
BACE1 RNA interference improves spatial memory and attenuates Aβ burden in a streptozotocin-induced tau hyperphosphorylated rat modelQ48536047
Dual-functional nanoparticles targeting amyloid plaques in the brains of Alzheimer's disease miceQ48954162
Dual-functional nanoparticles for precise drug delivery to Alzheimer's disease lesions: Targeting mechanisms, pharmacodynamics and safetyQ50442453
Lipoprotein-based nanoparticles rescue the memory loss of mice with Alzheimer's disease by accelerating the clearance of amyloid-betaQ50860708
PEGylation rate influences peptide-based nanoparticles mediated siRNA delivery in vitro and in vivo.Q51057526
A pharmacokinetic/pharmacodynamic comparison of SAAM II and PC/WinNonlin modeling software.Q52235136
[Progress of clinical trials in Alzheimer’s disease drugs]Q95579955
P4510describes a project that usesImageJQ1659584
P433issue3
P304page(s)590-603
P577publication date2018-12-30
P1433published inActa Pharmaceutica Sinica BQ26854022
P1476titleSmall interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer׳s disease
P478volume9

Reverse relations

cites work (P2860)
Q96305499Advances in nanotechnology-based strategies for the treatments of amyotrophic lateral sclerosis
Q102069112Mfn2 Overexpression Attenuates Cardio-Cerebrovascular Ischemia-Reperfusion Injury Through Mitochondrial Fusion and Activation of the AMPK/Sirt3 Signaling
Q90661070Role of mitochondrial quality control in the pathogenesis of nonalcoholic fatty liver disease
Q95266895Transferrin-Modified Osthole PEGylated Liposomes Travel the Blood-Brain Barrier and Mitigate Alzheimer's Disease-Related Pathology in APP/PS-1 Mice

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