Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease

scientific article published on 02 August 2019

Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3389/FCVM.2019.00089
P932PMC publication ID6688526
P698PubMed publication ID31428618

P50authorEileen M RedmondQ68093809
Paul CahillQ40515486
P2093author name stringIan L Megson
Denise Burtenshaw
Michael Kitching
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Reactive oxygen species in the activation of MAP kinasesQ38121267
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Roles of Nrf2 in cell proliferation and differentiationQ38539620
Involvement of Cytochrome P450 in Reactive Oxygen Species Formation and CancerQ38559099
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Human monocytes and macrophages express NADPH oxidase 5; a potential source of reactive oxygen species in atherosclerosis.Q38887518
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Interaction between ROS dependent DNA damage, mitochondria and p38 MAPK underlies senescence of human adult stem cellsQ38984158
Roles of Vascular Oxidative Stress and Nitric Oxide in the Pathogenesis of Atherosclerosis.Q39139744
The epigenetic landscape related to reactive oxygen species formation in the cardiovascular systemQ39195350
Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney DiseaseQ39401060
Human mesenchymal stem cells efficiently manage oxidative stressQ39716782
Snail is required for TGFbeta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cellsQ39939184
NADPH oxidase 4 contributes to connective tissue growth factor expression through Smad3-dependent signaling pathwayQ39945794
Phosphatidylinositol 3-kinase-dependent membrane recruitment of Rac-1 and p47phox is critical for alpha-platelet-derived growth factor receptor-induced production of reactive oxygen speciesQ40037121
Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cellsQ40089541
Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular RemodelingQ40159980
Glutathione peroxidase-1 activity, atherosclerotic burden, and cardiovascular prognosisQ40235285
Turning point in apoptosis/necrosis induced by hydrogen peroxideQ40271422
Epidermal growth factor as a candidate for ex vivo expansion of bone marrow-derived mesenchymal stem cellsQ40375826
Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents AtherosclerosisQ40623445
Effects of Antioxidant Supplements on the Survival and Differentiation of Stem CellsQ41099472
Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis ModelsQ30831517
NADPH oxidases in vascular pathologyQ33632089
NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transductionQ33666145
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Pathways that Regulate ROS Scavenging Enzymes, and Their Role in Defense Against Tissue Destruction in PeriodontitisQ33736736
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NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinasesQ33834313
Superoxide and iron: partners in crimeQ33905586
Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS releaseQ33913079
Vascular signaling through G protein-coupled receptors: new conceptsQ33942342
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Glutathione peroxidase 1 protects mitochondria against hypoxia/reoxygenation damage in mouse heartsQ34105777
Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncouplingQ34150616
Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunctionQ34268169
TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodelingQ34273145
Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cellsQ34283019
NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodelingQ34495678
Chronic cigarette smoking causes hypertension, increased oxidative stress, impaired NO bioavailability, endothelial dysfunction, and cardiac remodeling in miceQ34502041
Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell ActivationQ34524163
Cell signaling. H2O2, a necessary evil for cell signalingQ34543124
Function and design of the Nox1 system in vascular smooth muscle cellsQ34623486
Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H2O2.Q34889421
Stem cells and the impact of ROS signalingQ34999296
Effects of oxidative stress on mouse embryonic stem cell proliferation, apoptosis, senescence, and self-renewalQ35082736
Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.Q35145481
Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.Q35247002
Crosstalk of reactive oxygen species and NF-κB signalingQ35347850
Free radical-mediated oxidation of free amino acids and amino acid residues in proteinsQ35602220
Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression: implication for native LDL oxidationQ35611252
Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migrationQ35766044
In stent restenosis: bane of the stent era.Q35769824
Snail Is a Direct Target of Hypoxia-inducible Factor 1α (HIF1α) in Hypoxia-induced Endothelial to Mesenchymal Transition of Human Coronary Endothelial Cells.Q35860512
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Plasma vitamins E and A inversely correlated to mortality from ischemic heart disease in cross-cultural epidemiologyQ41289206
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Determinants of atherosclerosis susceptibility in the C3H and C57BL/6 mouse model: evidence for involvement of endothelial cells but not blood cells or cholesterol metabolismQ41737918
ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescenceQ41821426
Previously differentiated medial vascular smooth muscle cells contribute to neointima formation following vascular injuryQ42035291
Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotypeQ42099958
Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instabilityQ42151771
Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9.Q42186142
ROS and Oxidative Stress in Stem CellsQ42361217
Cyclic strain-induced reactive oxygen species involved in ICAM-1 gene induction in endothelial cellsQ42450135
NF-kappaB activation stimulates osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue by increasing TAZ expressionQ42465301
Oxidative stress defense in human-skin-derived mesenchymal stem cells versus human keratinocytes: Different mechanisms of protection and cell selectionQ42472754
Bioavailable Concentrations of Delphinidin and Its Metabolite, Gallic Acid, Induce Antioxidant Protection Associated with Increased Intracellular Glutathione in Cultured Endothelial CellsQ42730608
Thiazolidinediones increase the wingless-type MMTV integration site family (WNT) inhibitor Dickkopf-1 in adipocytes: a link with osteogenesis.Q42831868
Platelet-derived exosomes induce endothelial cell apoptosis through peroxynitrite generation: experimental evidence for a novel mechanism of septic vascular dysfunctionQ43029801
NOX1-induced accumulation of reactive oxygen species in abdominal fat-derived mesenchymal stromal cells impinges on long-term proliferationQ43167021
Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complexQ43194871
Atorvastatin inhibits gp91phox circulating levels in patients with hypercholesterolemiaQ43228814
Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis.Q43247649
Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.Q43823904
Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injuryQ43852782
Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cellsQ43917503
Superoxide production and expression of nox family proteins in human atherosclerosisQ43933078
Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activationQ44022525
NAD(P)H oxidase mediates angiotensin II-induced vascular macrophage infiltration and medial hypertrophyQ44362025
Expression and localization of NOX2 and NOX4 in primary human endothelial cellsQ45261476
Role of oxidative stress in elevated blood pressure induced by high free fatty acidsQ46099844
The immunology of hypertension.Q46238640
The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in miceQ46250017
Nox, Reactive Oxygen Species and Regulation of Vascular Cell Fate.Q46261737
Adventitial Fibroblast Nox4 Expression and ROS Signaling in Pulmonary Arterial HypertensionQ46280910
Reactive oxygen species as mediators of sperm capacitation and pathological damage.Q46330055
TFEB inhibits endothelial cell inflammation and reduces atherosclerosisQ46425143
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory MacrophagesQ46485595
NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblastsQ46508038
Role of smooth muscle Nox4-based NADPH oxidase in neointimal hyperplasiaQ46637560
The antioxidant N-acetylcysteine promotes atherosclerotic plaque stabilization through suppression of RAGE, MMPs and NF-κB in ApoE-deficient miceQ46750048
Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cellsQ46755210
Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic miceQ46757550
Uncoupled endothelial nitric oxide synthase and oxidative stress in a rat model of pregnancy-induced hypertensionQ46874860
Reactive oxygen species regulate the quiescence of CD34-positive cells derived from human embryonic stem cellsQ46903669
A Gli(1)ttering Role for Perivascular Stem Cells in Blood Vessel RemodelingQ46982352
Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4-MD2 complex.Q47139181
Endothelial NADPH oxidase-2 promotes interstitial cardiac fibrosis and diastolic dysfunction through proinflammatory effects and endothelial-mesenchymal transition.Q47219984
Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiologyQ47327835
DJ-1 Regulates Differentiation of Human Mesenchymal Stem Cells into Smooth Muscle-like Cells in Response to SphingosylphosphorylcholineQ47742435
Adult Stem Cells in Vascular RemodelingQ49169401
Accelerated atherogenesis in completely ligated common carotid artery of apolipoprotein E-deficient mice.Q49334737
Mitochondrial DNA damage and reactive oxygen species in neurodegenerative disease.Q49556815
Cellular death, reactive oxygen species (ROS) and diabetic complicationsQ49679592
Redox control of vascular smooth muscle cell function and plasticityQ49789143
Shedding light on the cell biology of extracellular vesiclesQ50018560
The mechanism of stem cell differentiation into smooth muscle cellsQ50042938
Oxidative stress as a mediator of cardiovascular diseaseQ37780644
Resident intimal dendritic cells and the initiation of atherosclerosisQ37780935
CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intimaQ37835548
Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidasesQ37838705
Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF.Q35998014
Generation of reactive oxygen species in adipose-derived stem cells: friend or foe?Q36020772
The adventitia: a dynamic interface containing resident progenitor cells.Q36055619
Gp91(phox) is the heme binding subunit of the superoxide-generating NADPH oxidaseQ36165558
Hydrogen peroxide regulation of endothelial function: origins, mechanisms, and consequencesQ36189782
Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosisQ36228893
Contribution of Vascular Cells to Neointimal FormationQ36242582
Differentiation of multipotent vascular stem cells contributes to vascular diseasesQ36511596
Nox and Inflammation in the Vascular Adventitia.Q36569976
NADPH oxidases in the kidneyQ36598811
Endothelial NADPH oxidase 4 protects ApoE-/- mice from atherosclerotic lesionsQ36664698
Aging-related decrease of human ASC angiogenic potential is reversed by hypoxia preconditioning through ROS productionQ36673690
The vessel wall and its interactionsQ36677300
Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signalingQ36734687
Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2Q36809534
Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: enhancement by angiotensin IIQ36821496
Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of AP-1 activityQ36846449
Adventitial fibroblast reactive oxygen species as autacrine and paracrine mediators of remodeling: bellwether for vascular disease?Q36906269
Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage FunctionQ36940718
ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophagesQ36973955
Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells.Q36982611
Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout miceQ37088422
Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of Sp1 activityQ37156462
Phosphorylation of Nox1 regulates association with NoxA1 activation domain.Q37261114
Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosisQ37406316
Redox regulation of Janus kinase: The elephant in the roomQ37421820
Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injuryQ37426292
Reactive oxygen species in cancerQ37431048
NOX Activation by Subunit Interaction and Underlying Mechanisms in DiseaseQ37574976
Correlation between carotid intimal/medial thickness and atherosclerosis: a point of view from pathologyQ37579479
Macrophage mitochondrial oxidative stress promotes atherosclerosis and nuclear factor-κB-mediated inflammation in macrophages.Q37624935
NOX4 downregulation leads to senescence of human vascular smooth muscle cells.Q37687002
Role of NADPH Oxidase-4 in Human Endothelial Progenitor CellsQ37716821
TGF-β1 Pretreatment Improves the Function of Mesenchymal Stem Cells in the Wound Bed.Q37736124
Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models.Q37760616
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectreactive oxygen speciesQ424361
P304page(s)89
P577publication date2019-08-02
P1433published inFrontiers in cardiovascular medicineQ27726930
P1476titleReactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease
P478volume6

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cites work (P2860)
Q96303466Fibroblast Growth Factor 19 Levels Predict Subclinical Atherosclerosis in Men With Type 2 Diabetes
Q96345435Molecular hydrogen improves type 2 diabetes through inhibiting oxidative stress
Q97523676NOX2 Is Critical to Endocardial to Mesenchymal Transition and Heart Development
Q99629066Time-dependent replicative senescence vs. disturbed flow-induced pre-mature aging in atherosclerosis
Q95856528Unveiling the Role of Inflammation and Oxidative Stress on Age-Related Cardiovascular Diseases

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