IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints

scientific article published on 24 January 2020

IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1073/PNAS.1914186117
P932PMC publication ID7022208
P698PubMed publication ID31980518

P50authorBruno RaposoQ87988465
Gustaf WigerbladQ92732351
Long JiangQ92931570
Yanek Jiménez-AndradeQ92931575
Vaishnavi Srinivasan IyerQ92931579
Yunbing ShenQ92931583
Sanjaykumar V BoddulQ92931587
Zsolt KaszaQ92931591
André Ortlieb Guerreiro-CacaisQ55860372
Fredrik WermelingQ81347347
Sudeepta K PandaQ84054951
P2860cites workThe murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1Q24310131
Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functionsQ24532135
Extra-articular disease manifestations in rheumatoid arthritis: incidence trends and risk factors over 46 yearsQ24674079
History of interleukin-4Q28085747
The IL-4 receptor: signaling mechanisms and biologic functionsQ28198739
Introduction to NF-kappaB: players, pathways, perspectivesQ28271022
The Genotype-Tissue Expression (GTEx) projectQ28657968
Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1Q28741941
Fcgamma receptors as regulators of immune responsesQ29615584
Stattic: a small-molecule inhibitor of STAT3 activation and dimerizationQ33264035
In vivo effector functions of high-affinity mouse IgG receptor FcγRI in disease and therapy modelsQ33436030
Immune inhibitory receptorsQ34054933
Antibody-based delivery of IL4 to the neovasculature cures mice with arthritisQ34083054
Rheumatoid arthritisQ87726283
Regulation of neutrophils in type 2 immune responsesQ90271381
Neutrophils in Rheumatoid Arthritis: Breaking Immune Tolerance and Fueling DiseaseQ91310929
IL-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formationQ91623128
IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In VivoQ92228710
Risk of infection in patients with atopic dermatitis treated with dupilumab: A meta-analysis of randomized controlled trialsQ47682896
IL-10 stimulates monocyte Fc gamma R surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10Q50335926
TH2 cell development and function.Q52862184
Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis.Q54001255
Suppression of collagen-induced arthritis by continuous administration of IL-4.Q54499617
A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritisQ62817447
Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factorQ71645449
Flare of arthritis with successful treatment of Felty's syndrome with granulocyte colony stimulating factor (GCSF)Q71697917
Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient miceQ71814481
High serum and synovial fluid granulocyte colony stimulating factor (G-CSF) concentrations in patients with rheumatoid arthritisQ73345428
Interleukin-4 regulates proteoglycan-induced arthritis by specifically suppressing the innate immune responseQ79850138
Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoterQ34161873
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulinQ34166632
Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine modelQ34365089
Differential regulation of IL-4Ralpha expression by antigen versus cytokine stimulation characterizes Th2 progression in vivoQ34732223
The Immunological Genome Project: networks of gene expression in immune cells.Q34830433
Immune complexes from rheumatoid arthritis synovial fluid induce FcgammaRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor-alpha by peripheral blood mononuclear cellsQ34897560
The role of neutrophils in type II collagen-induced arthritis in ratsQ35858503
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.Q35896845
Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signalingQ36414844
Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway.Q36959840
Th2 and eosinophil responses suppress inflammatory arthritisQ36985624
NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritisQ37056181
Acute inflammation primes myeloid effector cells for anti-inflammatory STAT6 signalingQ37104028
Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expressionQ37387939
Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factorQ37571189
Novel roles for the IgG Fc glycanQ37979848
The influence of ACPA status and characteristics on the course of RA.Q37980340
The role of neutrophils in autoimmune diseases.Q37985351
Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritisQ38235035
Inhibitory Fcγ receptor is required for the maintenance of tolerance through distinct mechanismsQ38538598
The multi-subunit interleukin-2 receptorQ38686728
Feedback Amplification of Neutrophil FunctionQ38829081
Signaling by Antibodies: Recent ProgressQ39264890
Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.Q39804205
Rheumatoid arthritis. The role of neutrophil activation.Q40077860
Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.Q40468456
Type 2 Interleukin-4 Receptor Signaling in Neutrophils Antagonizes Their Expansion and Migration during Infection and Inflammation.Q40606145
Regulated expression and inhibitory function of Fcgamma RIIb in human monocytic cellsQ40763824
Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritisQ41546325
Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteinsQ41825751
Transdifferentiation of polymorphonuclear neutrophils to dendritic-like cells at the site of inflammation in rheumatoid arthritis: evidence for activation by T cellsQ42066136
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullinationQ42676934
MH-S, a murine alveolar macrophage cell line: morphological, cytochemical, and functional characteristicsQ42816858
Neutrophil granulocyte-committed cells can be driven to acquire dendritic cell characteristics.Q42971524
Induction and suppression of collagen-induced arthritis is dependent on distinct fcgamma receptorsQ42972699
Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8.Q43832946
Arthritis critically dependent on innate immune system playersQ43899243
The role of FcgammaR signaling in the K/B x N serum transfer model of arthritisQ44223932
Intra-articular IL-4 gene therapy in arthritis: anti-inflammatory effect and enhanced th2activityQ45864635
Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology.Q46899191
Green listed-a CRISPR screen toolQ47348928
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 4.0 InternationalQ24082749
P6216copyright statuscopyrightedQ50423863
P433issue6
P304page(s)3103-3113
P577publication date2020-01-24
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleIL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints
P478volume117

Reverse relations

cites work (P2860)
Q99579418Designing custom CRISPR libraries for hypothesis-driven drug target discovery
Q90092058Evolution and function of interleukin-4 receptor signaling in adaptive immunity and neutrophils

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