Direct evidence that neural cell adhesion molecule (NCAM) polysialylation increases intermembrane repulsion and abrogates adhesion

scientific article published on 25 October 2004

Direct evidence that neural cell adhesion molecule (NCAM) polysialylation increases intermembrane repulsion and abrogates adhesion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M410216200
P698PubMed publication ID15504723

P50authorColin P JohnsonQ60023860
P2093author name stringDeborah E Leckband
Ichiro Fujimoto
Urs Rutishauser
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell adhesionQ187640
P1104number of pages9
P304page(s)137-145
P577publication date2004-10-25
P1433published inJournal of Biological ChemistryQ867727
P1476titleDirect evidence that neural cell adhesion molecule (NCAM) polysialylation increases intermembrane repulsion and abrogates adhesion
P478volume280

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cites work (P2860)
Q46269208A biosynthetic route for polysialylating proteins in Escherichia coli.
Q94671558Aberrant glycosylation in schizophrenia: a review of 25 years of post-mortem brain studies
Q46891038Activity-dependent PSA expression regulates inhibitory maturation and onset of critical period plasticity.
Q33763641Annotation and structural analysis of sialylated human milk oligosaccharides
Q38319100Antagonist-induced deadhesion of specifically adhered vesicles
Q99561987Brain region-dependent alterations in polysialic acid immunoreactivity across the estrous cycle in mice
Q41791559Cellular morphogenesis in silico
Q27865230Cryo-electron tomography of homophilic adhesion mediated by the neural cell adhesion molecule L1.
Q36912760Development of GABA innervation in the cerebral and cerebellar cortices.
Q30490406Developmental regulation of GABAergic interneuron branching and synaptic development in the prefrontal cortex by soluble neural cell adhesion molecule
Q50668988Dynamic expression of the polysialyltransferase in adult rat hippocampus performing an olfactory associative task.
Q30493156Ectopic expression of polysialylated neural cell adhesion molecule in adult macaque Schwann cells promotes their migration and remyelination potential in the central nervous system
Q35235389Effects of polysialic acid on sensory innervation of the cornea
Q37282253Elasticity and rupture of a multi-domain neural cell adhesion molecule complex
Q36294720Enzymatic engineering of polysialic acid on cells in vitro and in vivo using a purified bacterial polysialyltransferase
Q35086401EpCAM and the biology of hepatic stem/progenitor cells
Q48339195Epithelial-mesenchymal transition, and collective and individual cell migration regulate epithelial changes in the amikacin-damaged organ of Corti
Q35921432Expression and localization of neural cell adhesion molecule and polysialic acid during chick corneal development
Q42328167GFRα1 Regulates Purkinje Cell Migration by Counteracting NCAM Function
Q28566194Gangliogenesis in the enteric nervous system: roles of the polysialylation of the neural cell adhesion molecule and its regulation by bone morphogenetic protein-4
Q34988382Glycan elongation beyond the mucin associated Tn antigen protects tumor cells from immune-mediated killing
Q33659849Glycobiology of neuroblastoma: impact on tumor behavior, prognosis, and therapeutic strategies
Q37257286Identification of sequences in the polysialyltransferases ST8Sia II and ST8Sia IV that are required for the protein-specific polysialylation of the neural cell adhesion molecule, NCAM.
Q36065635Imaging the sialome during zebrafish development with copper-free click chemistry
Q47915102In silico zebrafish pattern formation
Q42205218In vivo activation of channelrhodopsin-2 reveals that normal patterns of spontaneous activity are required for motoneuron guidance and maintenance of guidance molecules
Q37368944Increased cell-intrinsic excitability induces synaptic changes in new neurons in the adult dentate gyrus that require Npas4
Q38877606Insulin promotes cell migration by regulating PSA-NCAM.
Q36370665Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells
Q41037155Is Polysialylated NCAM Not Only a Regulator during Brain Development But also during the Formation of Other Organs?
Q50679286Lentiviral-mediated expression of polysialic acid in spinal cord and conditioning lesion promote regeneration of sensory axons into spinal cord.
Q37914014Molecular mechanisms underlying activity-dependent GABAergic synapse development and plasticity and its implications for neurodevelopmental disorders
Q38089692NCAM function in the adult brain: lessons from mimetic peptides and therapeutic potential
Q39146371NCAM polysialylation during adherence transitions: live cell monitoring using an antibody-mimetic EGFP-endosialidase and the viability dye DRAQ7.
Q28071519NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being?
Q36288517Neural cell adhesion molecule (NCAM) marks adult myogenic cells committed to differentiation
Q40153294Neural cell adhesion molecule and its polysialic acid moiety exhibit opposing and linked effects on neuropathic hyperalgesia
Q42408100Neural cell adhesion molecule and polysialic acid in ductular reaction: the puzzle is far from completed, but the picture is becoming more clear
Q34283502Neural cell adhesion molecule, NCAM, regulates thalamocortical axon pathfinding and the organization of the cortical somatosensory representation in mouse
Q36692831Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration
Q35885507Neuraminidase-Dependent Degradation of Polysialic Acid Is Required for the Lamination of Newly Generated Neurons
Q88783780Neutrophil-mediated delivery of pixantrone-loaded liposomes decorated with poly(sialic acid)-octadecylamine conjugate for lung cancer treatment
Q28535224Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration
Q37048744Polysialic Acid Acute Depletion Induces Structural Plasticity in Interneurons and Impairs the Excitation/Inhibition Balance in Medial Prefrontal Cortex Organotypic Cultures
Q37174220Polysialic acid and activity-dependent synapse remodeling
Q81442433Polysialic acid controls NCAM-induced differentiation of neuronal precursors into calretinin-positive olfactory bulb interneurons
Q37274355Polysialic acid governs T-cell development by regulating progenitor access to the thymus
Q37024530Polysialic acid in the plasticity of the developing and adult vertebrate nervous system
Q27310462Polysialic acid is required for dopamine D2 receptor-mediated plasticity involving inhibitory circuits of the rat medial prefrontal cortex
Q33539425Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines
Q42554621Polysialic acid on neuropilin-2 is exclusively synthesized by the polysialyltransferase ST8SiaIV and attached to mucin-type o-glycans located between the b2 and c domain.
Q40804012Polysialic acid-directed migration and differentiation of neural precursors are essential for mouse brain development
Q30502915Polysialic acid-induced plasticity reduces neuropathic insult to the central nervous system
Q53064235Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury.
Q38077108Polysialic acid: versatile modification of NCAM, SynCAM 1 and neuropilin-2.
Q36443994Polysialylated NCAM and ephrinA/EphA regulate synaptic development of GABAergic interneurons in prefrontal cortex
Q30492039Polysialylated-neural cell adhesion molecule (PSA-NCAM) in the human trigeminal ganglion and brainstem at prenatal and adult ages.
Q35231280Polysialylation of NCAM characterizes the proliferation period of contractile elements during postnatal development of the epididymis
Q34667113Post-training intrahippocampal injection of synthetic poly-alpha-2,8-sialic acid-neural cell adhesion molecule mimetic peptide improves spatial long-term performance in mice
Q83292612Promoting survival, migration, and integration of transplanted Schwann cells by over-expressing polysialic acid
Q35793921Protracted brain development in a rodent model of extreme longevity.
Q36368216Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis.
Q41892280ST8SIA4-Dependent Polysialylation is Part of a Developmental Program Required for Germ Layer Formation from Human Pluripotent Stem Cells
Q34034708Sensory experience differentially modulates the mRNA expression of the polysialyltransferases ST8SiaII and ST8SiaIV in postnatal mouse visual cortex
Q36849985Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV and Polysialylation of Its O-Glycans.
Q34575750Sequences at the interface of the fifth immunoglobulin domain and first fibronectin type III repeat of the neural cell adhesion molecule are critical for its polysialylation
Q34251447Sequences from the first fibronectin type III repeat of the neural cell adhesion molecule allow O-glycan polysialylation of an adhesion molecule chimera
Q35838994Sequences prior to conserved catalytic motifs of polysialyltransferase ST8Sia IV are required for substrate recognition
Q36908164Sialic acids in human health and disease
Q26995291Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration
Q39384755Sialidase NEU4 hydrolyzes polysialic acids of neural cell adhesion molecules and negatively regulates neurite formation by hippocampal neurons
Q35108263Similarities between heterophilic and homophilic cadherin adhesion
Q38120363Simple rules for a "simple" nervous system? Molecular and biomathematical approaches to enteric nervous system formation and malformation
Q27662651Structure and Mutagenesis of Neural Cell Adhesion Molecule Domains: EVIDENCE FOR FLEXIBILITY IN THE PLACEMENT OF POLYSIALIC ACID ATTACHMENT SITES
Q33933086Synaptic cell adhesion molecule SynCAM 1 is a target for polysialylation in postnatal mouse brain
Q37042625The Neurofilament-Derived Peptide NFL-TBS.40-63 Targets Neural Stem Cells and Affects Their Properties
Q41566450The Polybasic Region of the Polysialyltransferase ST8Sia-IV Binds Directly to the Neural Cell Adhesion Molecule, NCAM.
Q36758232The effect of glycomimetic functionalized collagen on peripheral nerve repair
Q89624349The manifold roles of sialic acid for the biological functions of endothelial glycoproteins
Q36666264The polysialyltransferases interact with sequences in two domains of the neural cell adhesion molecule to allow its polysialylation
Q37574378The rostral migratory stream and olfactory system: smell, disease and slippery cells.
Q92420133Transgenic overexpression of polysialyltransferase ST8SiaIV under the control of a neuron-specific promoter does not affect brain development but impairs exploratory behavior
Q35130851Use of polysialic acid in repair of the central nervous system
Q47847883WITHDRAWN: Use of PSA-NCAM in Repair of the Central Nervous System
Q83878452[Mixed endocrine tumors]