Hepatic Macrophages in Liver Injury

scientific article published on 17 April 2020

Hepatic Macrophages in Liver Injury is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3389/FIMMU.2020.00322
P932PMC publication ID7180226
P698PubMed publication ID32362892

P2093author name stringCynthia Ju
Zhao Shan
P2860cites workExtracellular HSPs: The Complicated Roles of Extracellular HSPs in ImmunityQ26747413
Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS.Q27309031
CXCL6-EGFR-induced Kupffer cells secrete TGF-β1 promoting hepatic stellate cell activation via the SMAD2/BRD4/C-MYC/EZH2 pathway in liver fibrosisQ58779664
Pathogen- or damage-associated molecular patterns during nonalcoholic fatty liver disease developmentQ62066924
Apoptosis of neutrophils and their elimination by Kupffer cells in rat liverQ71748790
ICAM-1 triggers liver regeneration through leukocyte recruitment and Kupffer cell-dependent release of TNF-alpha/IL-6 in miceQ73069453
Scavenger receptors on liver Kupffer cells mediate the in vivo uptake of oxidatively damaged red blood cells in miceQ73520952
Role of free radicals in primary nonfunction of marginal fatty grafts from rats treated acutely with ethanolQ73833663
Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the ratQ73939862
Complementary adhesion molecules promote neutrophil-Kupffer cell interaction and the elimination of bacteria taken up by the liverQ77373935
Heat-shock proteins as activators of the innate immune systemQ77689830
Oxidative-stress and IL-6 mediate the fibrogenic effects of [corrected] Kupffer cells on stellate cellsQ79390715
Apoptotic cells attenuate fulminant hepatitis by priming Kupffer cells to produce interleukin-10 through membrane-bound TGF-βQ82795328
Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in miceQ84646403
Effect of Kupffer cells on immune tolerance in liver transplantationQ85581759
Dynamics and genomic landscape of CD8+ T cells undergoing hepatic primingQ90468424
The Role of Macrophage Migration Inhibitory Factor in Remote Ischemic Conditioning Induced Hepatoprotection in a Rodent Model of Liver TransplantationQ90848288
Fatty acid activates NLRP3 inflammasomes in mouse Kupffer cells through mitochondrial DNA releaseQ90924809
Involvement of CCL2/CCR2 macrophage recruitment in amodiaquine-induced liver injuryQ91138744
Contribution of Macrophage Efferocytosis to Liver Homeostasis and DiseaseQ91670684
Hepatitis B virus-induced modulation of liver macrophage function promotes hepatocyte infectionQ92205074
Endoplasmic Reticulum Stress Causes Liver Cancer Cells to Release Exosomal miR-23a-3p and Up-regulate Programmed Death Ligand 1 Expression in MacrophagesQ92259680
HMGB1 and injury amplification.Q43112066
High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivoQ43270651
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenaseQ43664739
Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defectsQ43833399
Kupffer cells and activation of endothelial TLR4 coordinate neutrophil adhesion within liver sinusoids during endotoxemiaQ46065423
Reciprocal activation between CD4+ T cells and Kupffer cells during hepatic ischemia-reperfusion.Q46367995
Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intakeQ46473255
The liverQ47430653
Infiltrating monocyte-derived macrophages and resident kupffer cells display different ontogeny and functions in acute liver injury.Q48281671
Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease.Q49506021
Intracellular ATP Decrease Mediates NLRP3 Inflammasome Activation upon Nigericin and Crystal Stimulation.Q50915077
Dysregulated miR-124 and miR-200 expression contribute to cholangiocyte proliferation in the cholestatic liver by targeting IL-6/STAT3 signalling.Q51003408
Hyaluronic acid uptake by the isolated, perfused rat liver: an index of hepatic sinusoidal endothelial cell function.Q51602169
M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease.Q51743027
STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity.Q52575315
Role of gp91phox in hepatic macrophage programming and alcoholic liver disease.Q52733597
Liver inflammation abrogates immunological tolerance induced by Kupffer cells.Q52956130
Acute liver failureQ56430379
Bile Acids Activated Receptors Regulate Innate ImmunityQ57111959
Interleukin-10 expression is autoregulated at the transcriptional level in human and murine kupffer cellsQ57236228
Danger-Associated Molecular Patterns (DAMPs): Molecular Triggers for Sterile Inflammation in the LiverQ57478272
The biology of NKT cellsQ28277482
Molecular identification of a danger signal that alerts the immune system to dying cellsQ29619497
A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury.Q30401463
In vivo analysis of dendritic cell development and homeostasisQ30492687
Comparison of gene expression profiles between human and mouse monocyte subsetsQ33608738
The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in miceQ33653566
Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease.Q33905038
The liver as a site of T-cell apoptosis: graveyard, or killing field?Q33916575
Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cellsQ34045921
Chronic alcohol ingestion modulates hepatic macrophage populations and functions in miceQ34178620
mRNA is an endogenous ligand for Toll-like receptor 3.Q34290592
High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activityQ34400931
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.Q34659689
IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and diseaseQ34697945
The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosisQ35056726
Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell deathQ35061420
GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells.Q35155033
Toll-like receptor 4 (TLR4) antagonist eritoran tetrasodium attenuates liver ischemia and reperfusion injury through inhibition of high-mobility group box protein B1 (HMGB1) signalingQ35192812
The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in miceQ35249092
Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in miceQ35541859
Oral ampicillin inhibits liver regeneration by breaking hepatic innate immune tolerance normally maintained by gut commensal bacteriaQ35580065
Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment.Q35623089
Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferationQ35750826
Hepatic stellate cells orchestrate clearance of necrotic cells in a hypoxia-inducible factor-1α-dependent manner by modulating macrophage phenotype in miceQ35962200
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.Q36000076
Defective Initiation of Liver Regeneration in Osteopontin-Deficient Mice after Partial Hepatectomy due to Insufficient Activation of IL-6/Stat3 PathwayQ36002104
Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitisQ36168809
The origin and kinetics of mononuclear phagocytesQ36269269
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusionQ36403403
Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosisQ36414956
MicroRNA Cargo of Extracellular Vesicles from Alcohol-exposed Monocytes Signals Naive Monocytes to Differentiate into M2 Macrophages.Q36419227
Macrophage activation by factors released from acetaminophen-injured hepatocytes: potential role of HMGB1Q36426198
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cellsQ36534480
Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles.Q36600231
Role of Kupffer cells in host defense and liver diseaseQ36653858
Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategiesQ36870030
TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory eventsQ36946570
Mechanism of T cell tolerance induction by murine hepatic Kupffer cellsQ37010267
Liver: An organ with predominant innate immunityQ37048206
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liverQ37117562
Kupffer cells in non-alcoholic fatty liver disease: the emerging view.Q37222183
CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammationQ37234292
Specification of tissue-resident macrophages during organogenesis.Q37343167
Emerging role of high-mobility group box 1 (HMGB1) in liver diseasesQ37446034
Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposalQ37503524
Endotoxemia and gut barrier dysfunction in alcoholic liver diseaseQ37539842
Toll-like receptor signaling in liver ischemia and reperfusionQ38031294
Immune and inflammatory pathways in NASH.Q38192633
Macrophages: central regulators of iron balanceQ38218243
Cellular and molecular functions of hepatic stellate cells in inflammatory responses and liver immunologyQ38311151
Hematopoietic stem cells: concepts, definitions, and the new reality.Q38374442
TGR5 and Immunometabolism: Insights from Physiology and PharmacologyQ38626278
Innate Immunity and Inflammation in NAFLD/NASH.Q38721837
Liver macrophages in healthy and diseased liverQ38745740
Role of hepatic macrophages in alcoholic liver diseaseQ38887445
The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosineQ38912682
Role of the G Protein-Coupled Bile Acid Receptor TGR5 in Liver DamageQ39156513
Liver macrophages in tissue homeostasis and diseaseQ39187324
Does niche competition determine the origin of tissue-resident macrophages?Q39276574
Mechanisms of hepatic stellate cell activationQ39294420
Mechanisms of bile acid mediated inflammation in the liverQ39367594
Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell lineQ40921479
Impaired monocyte-macrophage functions and defective Toll-like receptor signaling in hepatitis E virus-infected pregnant women with acute liver failureQ41020103
Kupffer Cells Support Hepatitis B Virus-Mediated CD8+ T Cell Exhaustion via Hepatitis B Core Antigen-TLR2 Interactions in MiceQ41034973
Kupffer cell-monocyte communication is essential for initiating murine liver progenitor cell-mediated liver regenerationQ41109061
Kupffer cells induce Notch-mediated hepatocyte conversion in a common mouse model of intrahepatic cholangiocarcinomaQ41290820
Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult AnimalsQ41363699
Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1β in miceQ41548774
Liver immunology: new perspectivesQ41782144
Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouseQ41962922
Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearanceQ42382293
Immune tolerance in liver diseaseQ43077728
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P921main subjectcell communicationQ14860133
P304page(s)322
P577publication date2020-04-17
P1433published inFrontiers in ImmunologyQ27723748
P1476titleHepatic Macrophages in Liver Injury
P478volume11

Reverse relations

Q97536540Kupffer cells promote T-cell hepatitis by producing CXCL10 and limiting liver sinusoidal endothelial cell permeabilitycites workP2860

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