HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo

scientific article published on 14 May 2020

HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41419-020-2580-3
P932PMC publication ID7224392
P698PubMed publication ID32409664

P50authorClaudia CrosioQ59661658
P2093author name stringGianluca Cestra
Ciro Iaccarino
Simona Sanna
Alessandra Masala
Manuela Galioto
Sonia Esposito
Milena Fais
Paola Sini
Gabriele Nieddu
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TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expressionQ39447231
Randomized sequential trial of valproic acid in amyotrophic lateral sclerosisQ39948325
Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse modelQ40128564
Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone programQ41061545
Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.Q41469956
Pur-alpha functionally interacts with FUS carrying ALS-associated mutations.Q41880989
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patientsQ42261802
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The histone deacetylase Rpd3 regulates the heterochromatin structure of Drosophila telomeres.Q52721476
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Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse modelQ91660695
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RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43Q92072992
Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell DeathQ92251814
P433issue5
P304page(s)369
P577publication date2020-05-14
P1433published inCell Death and DiseaseQ2197222
P1476titleHDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo
P478volume11

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