scholarly article | Q13442814 |
P50 | author | Claudia Crosio | Q59661658 |
P2093 | author name string | Gianluca Cestra | |
Ciro Iaccarino | |||
Simona Sanna | |||
Alessandra Masala | |||
Manuela Galioto | |||
Sonia Esposito | |||
Milena Fais | |||
Paola Sini | |||
Gabriele Nieddu | |||
P2860 | cites work | Genome engineering using the CRISPR-Cas9 system | Q22122027 |
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs | Q24317451 | ||
TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression | Q24318430 | ||
Clinical and experimental applications of sodium phenylbutyrate | Q24613511 | ||
HDAC signaling in neuronal development and axon regeneration | Q27013969 | ||
Axon injury induced endoplasmic reticulum stress and neurodegeneration | Q28068989 | ||
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis | Q28131672 | ||
Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue | Q28475724 | ||
HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage | Q28569045 | ||
Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes | Q28576708 | ||
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis | Q29616311 | ||
TDP-43 is a transcriptional repressor: the testis-specific mouse acrv1 gene is a TDP-43 target in vivo | Q30427637 | ||
A Drosophila model for TDP-43 proteinopathy | Q33733651 | ||
Modelling amyotrophic lateral sclerosis: progress and possibilities | Q33746289 | ||
Amino acids control mammalian gene transcription: activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter | Q33965767 | ||
Astroglial inhibition of NF-κB does not ameliorate disease onset and progression in a mouse model for amyotrophic lateral sclerosis (ALS) | Q34698706 | ||
Histone deacetylase inhibitors: possible implications for neurodegenerative disorders | Q34743081 | ||
Collaborative spirit of histone deacetylases in regulating chromatin structure and gene expression | Q35097666 | ||
Identification of differentially expressed plasma proteins in atherosclerotic patients with type 2 diabetes. | Q35977362 | ||
Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways. | Q36179578 | ||
Histone deacetylase-1 (HDAC1) is a molecular switch between neuronal survival and death | Q36318929 | ||
TDP-43 and FUS en route from the nucleus to the cytoplasm | Q36336278 | ||
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models | Q36434528 | ||
TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration | Q36509977 | ||
Histone deacetylase inhibitors as therapeutics for polyglutamine disorders | Q36599926 | ||
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss | Q36906420 | ||
Atrophin-Rpd3 complex represses Hedgehog signaling by acting as a corepressor of CiR. | Q37343914 | ||
Multiple roles of HDAC inhibition in neurodegenerative conditions. | Q37407855 | ||
Rethinking ALS: the FUS about TDP-43. | Q37419912 | ||
Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage | Q37474001 | ||
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects | Q37609639 | ||
Histone acetylation as a potential therapeutic target in motor neuron degenerative diseases. | Q38085378 | ||
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders | Q38240733 | ||
An acetylation switch controls TDP-43 function and aggregation propensity | Q38301905 | ||
Amyotrophic lateral sclerosis: mechanisms and therapeutics in the epigenomic era. | Q38431759 | ||
Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation. | Q38701633 | ||
Redox-sensitive GFP to monitor oxidative stress in neurodegenerative diseases | Q39061201 | ||
Transcription and Splicing Factor TDP-43: Role in Regulation of Gene Expression in Testis | Q39171204 | ||
TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expression | Q39447231 | ||
Randomized sequential trial of valproic acid in amyotrophic lateral sclerosis | Q39948325 | ||
Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model | Q40128564 | ||
Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program | Q41061545 | ||
Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons. | Q41469956 | ||
Pur-alpha functionally interacts with FUS carrying ALS-associated mutations. | Q41880989 | ||
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients | Q42261802 | ||
Tumour necrosis factor-alpha depletes histone deacetylase 1 protein through IKK2. | Q42704188 | ||
TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea. | Q45927072 | ||
Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis. | Q45934381 | ||
Phase 2 study of sodium phenylbutyrate in ALS. | Q46439340 | ||
Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice | Q46526611 | ||
Additive neuroprotective effects of a histone deacetylase inhibitor and a catalytic antioxidant in a transgenic mouse model of amyotrophic lateral sclerosis | Q46805732 | ||
RBM45 competes with HDAC1 for binding to FUS in response to DNA damage | Q47177294 | ||
Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis | Q48199277 | ||
TDP-43 post-translational modifications in health and disease | Q50069856 | ||
The histone deacetylase Rpd3 regulates the heterochromatin structure of Drosophila telomeres. | Q52721476 | ||
Amyotrophic lateral sclerosis | Q56531746 | ||
Epigenetic Changes Associated with the Expression of Amyotrophic Lateral Sclerosis (ALS) Causing Genes | Q57465369 | ||
Epigenetics in amyotrophic lateral sclerosis: a role for histone post-translational modifications in neurodegenerative disease | Q58571293 | ||
Functions and mechanisms of non-histone protein acetylation | Q63383559 | ||
The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD | Q64054884 | ||
The dark side of HDAC inhibition in ALS | Q64108167 | ||
Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis | Q64262571 | ||
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects | Q64387891 | ||
Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model | Q91660695 | ||
Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation | Q92060228 | ||
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43 | Q92072992 | ||
Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death | Q92251814 | ||
P433 | issue | 5 | |
P304 | page(s) | 369 | |
P577 | publication date | 2020-05-14 | |
P1433 | published in | Cell Death and Disease | Q2197222 |
P1476 | title | HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo | |
P478 | volume | 11 |
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