The numbers of peripheral regulatory T cells are reduced in patients with psoriatic arthritis and are restored by low-dose interleukin-2

scientific article published on 27 April 2020

The numbers of peripheral regulatory T cells are reduced in patients with psoriatic arthritis and are restored by low-dose interleukin-2 is …
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scholarly articleQ13442814

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P356DOI10.1177/2040622320916014
P932PMC publication ID7236566
P698PubMed publication ID32523664

P50authorJia WangQ91478360
P2093author name stringXiao-Feng Li
Jing Luo
Chong Gao
Yu-Yao Li
Sheng-Xiao Zhang
Meng-Ting Qiu
Yu-Fei Hao
P2860cites workEffects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and UveitisQ22299388
The IL-2 receptor complex: its structure, function, and target genesQ24324541
FOXP3+ regulatory T cells in the human immune systemQ29307487
Regulatory T cells and immune toleranceQ29616864
Immunomodulatory drugs and their application to the management of canine immune-mediated diseaseQ33393823
Low-dose interleukin-2 promotes STAT-5 phosphorylation, Treg survival and CTLA-4-dependent function in autoimmune liver diseasesQ33650813
Abatacept reduces synovial regulatory T-cell expression in patients with psoriatic arthritisQ33876826
The IL-2 defect in systemic lupus erythematosus disease has an expansive effect on host immunityQ33961011
Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferationQ33993967
The role of interleukin-2 during homeostasis and activation of the immune systemQ34255232
IL-17 in Chronic Inflammation: From Discovery to TargetingQ34512003
The biology of interleukin-2.Q34585827
The Proportion of Regulatory T Cells in Patients with Systemic Lupus Erythematosus: A Meta-AnalysisQ58766781
Effector Functions of CD4+ T Cells at the Site of Local Autoimmune Inflammation-Lessons From Rheumatoid ArthritisQ64102310
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor betaQ72287439
Classification criteria for psoriatic arthritis: development of new criteria from a large international studyQ80001900
Short-term and low-dose IL-2 therapy restores the Th17/Treg balance in the peripheral blood of patients with primary Sjögren's syndromeQ89219346
Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trialQ93347154
Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseasesQ34615216
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammationQ35242438
Rheumatic diseases in ChinaQ36641516
Effects of conventional immunosuppressive treatment on CD244+ (CD28null) and FOXP3+ T cells in the inflamed muscle of patients with polymyositis and dermatomyositisQ36758692
Th17 and Th22 cells in psoriatic arthritis and psoriasisQ37689670
Pathogenesis, classification and treatment of inflammatory myopathiesQ37862083
Regulatory T cells in nonlymphoid tissuesQ38139203
The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseasesQ38424758
Epigenetics of CD4+ T cells in autoimmune diseasesQ39211125
Th17 response and inflammatory autoimmune diseasesQ40110959
PD-1 modulates regulatory T-cell homeostasis during low-dose interleukin-2 therapyQ40354412
Macrophage-mediated psoriasis can be suppressed by regulatory T lymphocytesQ40533256
Treatment of dermatomyositis and polymyositis with anti-tumor necrosis factor-alpha: long-term follow-upQ44969103
Old and New Biological Therapies for Psoriasis.Q47859049
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P921main subjectpsoriatic arthritisQ511097
P304page(s)2040622320916014
P577publication date2020-04-27
P1433published inTherapeutic advances in chronic diseaseQ26842871
P1476titleThe numbers of peripheral regulatory T cells are reduced in patients with psoriatic arthritis and are restored by low-dose interleukin-2
P478volume11

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