Epigenetic and epitranscriptomic regulation of viral replication

scientific article published on 12 June 2020

Epigenetic and epitranscriptomic regulation of viral replication is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1038/S41579-020-0382-3
P932PMC publication ID7291935
P698PubMed publication ID32533130

P50authorKevin TsaiQ84819221
Bryan R. CullenQ95269610
P2860cites workDaxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeresQ24292850
EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcriptionQ24298061
IFI16 is an innate immune sensor for intracellular DNAQ24301720
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Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasionQ24339602
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IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modificationsQ28544797
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m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.Q33865334
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pre-mRNA processing includes N6 methylation of adenosine residues that are retained in mRNA exons and the fallacy of "RNA epigenetics".Q47340474
Positive-sense RNA viruses reveal the complexity and dynamics of the cellular and viral epitranscriptomes during infection.Q47548659
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N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection.Q54235221
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NP220 mediates silencing of unintegrated retroviral DNAQ59349655
N-Methyladenosine (mA): A Promising New Molecular Target in Acute Myeloid LeukemiaQ64063421
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Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression.Q64921408
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N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-IQ89519013
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First Days in the Life of Naive Human B Lymphocytes Infected with Epstein-Barr VirusQ90148663
FTSJ3 is an RNA 2'-O-methyltransferase recruited by HIV to avoid innate immune sensingQ90971072
Unintegrated HIV-1 DNAs are loaded with core and linker histones and transcriptionally silencedQ91104668
RNA modifications regulating cell fate in cancerQ91713119
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Nuclear Sensor Interferon-Inducible Protein 16 Inhibits the Function of Hepatitis B Virus Covalently Closed Circular DNA by Integrating Innate Immune Activation and Epigenetic SuppressionQ92553299
Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene ExpressionQ92639505
Regulation of Gene Expression by N6-methyladenosine in CancerQ92798817
Acetylation of Cytidine in mRNA Promotes Translation EfficiencyQ93199770
Reversal of Epigenetic Silencing Allows Robust HIV-1 Replication in the Absence of Integrase FunctionQ96125617
Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA StabilityQ96351025
Dynamic RNA Modifications in Gene Expression RegulationQ39378718
Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infectionQ39929078
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Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication.Q40041108
Epigenetic Regulation of Hepatitis B Virus Covalently Closed Circular DNA: Implications for Epigenetic Therapy against Chronic Hepatitis B.Q40073818
SP100B, a repressor of gene expression preferentially binds to DNA with unmethylated CpGs.Q40267659
PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase.Q40273699
Human cytomegalovirus (HCMV) UL82 gene product (pp71) relieves hDaxx-mediated repression of HCMV replicationQ40274324
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The viral ubiquitin ligase ICP0 is neither sufficient nor necessary for degradation of the cellular DNA sensor IFI16 during herpes simplex virus 1 infection.Q41894010
The histone variant H3.3 regulates gene expression during lytic infection with herpes simplex virus type 1.Q42066826
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Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle.Q45965685
5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C readerQ46550226
Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection.Q34594789
Herpes simplex virus ICP0 promotes both histone removal and acetylation on viral DNA during lytic infectionQ34848465
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The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infectionQ35846187
Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 ImmunosuppressionQ36040364
The emerging role of nuclear viral DNA sensorsQ36283649
Influenza viral mRNA contains internal N6-methyladenosine and 5'-terminal 7-methylguanosine in cap structuresQ36547480
A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latencyQ36591414
Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latencyQ36652895
PML and PML nuclear bodies: implications in antiviral defenceQ36753891
Perceiving the epigenetic landscape through histone readers.Q36821309
Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV ReplicationQ37364333
Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus InfectionQ37417352
Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latencyQ37439584
Folding and misfolding pathways of G-quadruplex DNA.Q37507665
Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteomeQ37568012
Proteins of purified Epstein-Barr virusQ37621844
The double face of the histone variant H3.3.Q37832128
Regulation of alphaherpesvirus infections by the ICP0 family of proteinsQ38067373
Disruption of host antiviral resistances by gammaherpesvirus tegument proteins with homology to the FGARAT purine biosynthesis enzymeQ38563262
Relative Contributions of Herpes Simplex Virus 1 ICP0 and vhs to Loss of Cellular IFI16 Vary in Different Human Cell TypesQ38758315
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Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor.Q38785882
Epigenetics and Genetics of Viral LatencyQ38833222
The Nuclear DNA Sensor IFI16 Acts as a Restriction Factor for Human Papillomavirus Replication through Epigenetic Modifications of the Viral Promoters.Q38875175
High-throughput single-base resolution mapping of RNA 2΄-O-methylated residuesQ38970734
Nuclear landscape of HIV-1 infection and integrationQ39035944
Histones Are Rapidly Loaded onto Unintegrated Retroviral DNAs Soon after Nuclear EntryQ39170765
Viral gene products actively promote latent infection by epigenetic silencing mechanismsQ39246210
P577publication date2020-06-12
2020-10-01
P1433published inNature Reviews MicrobiologyQ1071797
P1476titleEpigenetic and epitranscriptomic regulation of viral replication

Reverse relations

Q106452963Methyltransferase-like 3 modulates severe acute respiratory syndrome coronavirus-2 RNA N6-methyladenosine modification and replicationcites workP2860

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