N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection.

scientific article

N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1006995
P932PMC publication ID5919695
P698PubMed publication ID29659627

P50authorJohn Joseph KarijolichQ61312541
Charles R HesserQ88370663
Britt A GlaunsingerQ88370666
P2093author name stringChuan He
Dan Dominissini
P2860cites workN6-methyladenosine-dependent regulation of messenger RNA stabilityQ24310545
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Transcriptional activation by the product of open reading frame 50 of Kaposi's sarcoma-associated herpesvirus is required for lytic viral reactivation in B cellsQ39596534
Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposi's sarcoma-associated herpesvirusQ39729318
Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication.Q40041108
Identification and mapping of N6-methyladenosine containing sequences in Simian Virus 40 RNAQ40240837
Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expressionQ40537413
The methylation of adenovirus-specific nuclear and cytoplasmic RNA.Q40577581
N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.Q41432736
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesisQ41791644
Arabidopsis m(6)A demethylase activity modulates viral infection of a plant virus and the m(6)A abundance in its genomic RNAsQ41935079
m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transitionQ42130806
Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle.Q45965685
Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replicationQ49979102
RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune SignalingQ27468676
N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates InfectionQ27485442
Dynamics of Human and Viral RNA Methylation during Zika Virus InfectionQ27486503
5' UTR m(6)A Promotes Cap-Independent TranslationQ28114851
Nuclear m(6)A Reader YTHDC1 Regulates mRNA SplicingQ28114974
Dynamic m(6)A mRNA methylation directs translational control of heat shock responseQ28118495
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cellsQ28585513
N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expressionQ28828855
Cytoplasmic m6A reader YTHDF3 promotes mRNA translationQ29465772
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.Q29465801
Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genesQ30668574
Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.Q33555634
N6-methyladenosine alters RNA structure to regulate binding of a low-complexity proteinQ33741052
Kaposi's sarcoma-associated herpesvirus open reading frame 50/Rta protein activates the entire viral lytic cycle in the HH-B2 primary effusion lymphoma cell lineQ33807199
m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.Q33865334
The dynamic epitranscriptome: N6-methyladenosine and gene expression controlQ34414288
Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression.Q34523721
The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer CellsQ34523745
Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells.Q34538813
Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivatorQ34782463
Methylated simian virus 40-specific RNA from nuclei and cytoplasm of infected BSC-1 cellsQ35080272
Infection of lymphoblastoid cell lines by Kaposi's sarcoma-associated herpesvirus: critical role of cell-associated virusQ35383336
RNA modifications go viral.Q36302362
Influenza viral mRNA contains internal N6-methyladenosine and 5'-terminal 7-methylguanosine in cap structuresQ36547480
N(6)-Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein BindingQ36653832
YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complexQ37222906
Polyadenylylated nuclear RNA encoded by Kaposi sarcoma-associated herpesvirusQ37273424
KSHV 2.0: a comprehensive annotation of the Kaposi's sarcoma-associated herpesvirus genome using next-generation sequencing reveals novel genomic and functional featuresQ37488130
5'-Terminal and internal methylated nucleosides in herpes simplex virus type 1 mRNA.Q37506500
Genomewide mapping and screening of Kaposi's sarcoma-associated herpesvirus (KSHV) 3' untranslated regions identify bicistronic and polycistronic viral transcripts as frequent targets of KSHV microRNAsQ37547788
Gene expression regulation mediated through reversible m⁶A RNA methylationQ38198852
Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N6-Adenosine Methylation To Promote Lytic ReplicationQ38700916
RNA m6A methylation regulates the ultraviolet-induced DNA damage response.Q38712170
N (6)-Methyladenosine (m(6)A) Methylation in mRNA with A Dynamic and Reversible Epigenetic ModificationQ38834657
Viral Nucleases Induce an mRNA Degradation-Transcription Feedback Loop in Mammalian CellsQ38849238
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P304page(s)e1006995
P577publication date2018-04-16
P1433published inPLOS PathogensQ283209
P1476titleN6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection
P478volume14

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