scholarly article | Q13442814 |
P356 | DOI | 10.1038/S42255-020-0254-1 |
P698 | PubMed publication ID | 32719542 |
P50 | author | Douglas A. Melton | Q3038025 |
Erica P Cai | Q97905927 | ||
Peng Yi | Q97905932 | ||
Yuki Ishikawa | Q55979332 | ||
Nayara Carvalho Leite | Q60732717 | ||
S Kissler | Q73661227 | ||
Celia A. Schiffer | Q87706687 | ||
P2093 | author name string | Wei Zhang | |
Jian Li | |||
Shurong Hou | |||
Jennifer Hollister-Lock | |||
Nese Kurt Yilmaz | |||
Badr Kiaf | |||
P2860 | cites work | Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors | Q22008465 |
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes | Q24632382 | ||
Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis | Q24658203 | ||
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice | Q24670319 | ||
FAD-binding site and NADP reactivity in human renalase: a new enzyme involved in blood pressure regulation | Q27670535 | ||
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
Generation of functional human pancreatic β cells in vitro | Q28249536 | ||
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis | Q28306950 | ||
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes | Q28506402 | ||
Charting cellular identity during human in vitro β-cell differentiation | Q91865409 | ||
β-Cell Stress Shapes CTL Immune Recognition of Preproinsulin Signal Peptide by Posttranscriptional Regulation of Endoplasmic Reticulum Aminopeptidase 1 | Q92379190 | ||
An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes | Q92626522 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway | Q29547371 | ||
Genome-scale CRISPR-Cas9 knockout screening in human cells | Q29616044 | ||
Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes | Q30416530 | ||
Metabolic function for human renalase: oxidation of isomeric forms of β-NAD(P)H that are inhibitory to primary metabolism | Q33112688 | ||
Renalase prevents AKI independent of amine oxidase activity | Q33660611 | ||
Pancreatic islet-specific T-cell clones from nonobese diabetic mice | Q34313103 | ||
Identification of a receptor for extracellular renalase | Q34473401 | ||
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening | Q34553929 | ||
Improved vectors and genome-wide libraries for CRISPR screening | Q35215629 | ||
The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes | Q35787117 | ||
Are insights gained from NOD mice sufficient to guide clinical translation? Another inconvenient truth | Q36766166 | ||
Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice | Q36862098 | ||
Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells | Q38331321 | ||
The catalytic function of renalase: A decade of phantoms | Q38434446 | ||
Inherent ER stress in pancreatic islet β cells causes self-recognition by autoreactive T cells in type 1 diabetes | Q38771484 | ||
Endoplasmic reticulum stress in beta cells and autoimmune diabetes | Q38975660 | ||
Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome | Q39299566 | ||
Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus | Q39998473 | ||
NIT-1, a Pancreatic β-Cell Line Established From a Transgenic NOD/Lt Mouse | Q41678350 | ||
Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments | Q44012277 | ||
Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse | Q44286381 | ||
Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes. | Q46027530 | ||
The serum protein renalase reduces injury in experimental pancreatitis | Q47637402 | ||
Low HLA binding of diabetes-associated CD8+ T-cell epitopes is increased by post translational modifications. | Q52644342 | ||
Modifying Enzymes are Elicited by ER Stress, Generating Epitopes that are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes. | Q52719485 | ||
Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells | Q57173754 | ||
Therapies to Suppress β Cell Autoimmunity in Type 1 Diabetes | Q58773667 | ||
Following a diabetogenic T cell from genesis through pathogenesis | Q70488192 | ||
New inhibitor of monoamine oxidase | Q79080187 | ||
Peripherally induced regulatory T cells contribute to the control of autoimmune diabetes in the NOD mouse model | Q88232904 | ||
The challenge of modulating β-cell autoimmunity in type 1 diabetes | Q90350445 | ||
Generation of hypoimmunogenic human pluripotent stem cells | Q91651405 | ||
Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients | Q91691968 | ||
P921 | main subject | CRISPR | Q412563 |
P577 | publication date | 2020-07-27 | |
P1433 | published in | Nature Metabolism | Q96320741 |
P1476 | title | Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes |
Q98205329 | Protecting β-cells in type 1 diabetes | cites work | P2860 |
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