Vaccination Prevented Short-Term Memory Loss, but Deteriorated Long-Term Spatial Memory in Alzheimer's Disease Mice, Independent of Amyloid-β Pathology

scientific article published on 23 July 2020

Vaccination Prevented Short-Term Memory Loss, but Deteriorated Long-Term Spatial Memory in Alzheimer's Disease Mice, Independent of Amyloid-β Pathology is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3233/ADR-200213
P932PMC publication ID7458552
P698PubMed publication ID32904788

P2093author name stringUlrich L M Eisel
Regien G Schoemaker
Peter Hoogerhout
Leonie Gouweleeuw
Elly van Riet
Klaske Oberman
P2860cites workThe Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptideQ21090025
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Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behaviorQ24645994
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeuticsQ27860914
Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunizationQ28185520
Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampusQ28592777
A cyclic undecamer peptide mimics a turn in folded Alzheimer amyloid β and elicits antibodies against oligomeric and fibrillar amyloid and plaquesQ28740910
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formationQ29616564
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouseQ29619237
Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor proteinQ30499149
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's diseaseQ33292093
[Hippocampal and cognitive alterations precede amyloid deposition in a mouse model for Alzheimer's disease].Q50782883
Microglia in Alzheimer's diseaseQ56922819
Evaluation of the safety and immunogenicity of synthetic A 42 (AN1792) in patients with ADQ58005269
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A vaccine against Alzheimer`s disease: anything left but faith?Q90334385
The Time Course of Recognition Memory Impairment and Glial Pathology in the hAPP-J20 Mouse Model of Alzheimer's DiseaseQ91984521
Frustrated Alzheimer's researchers seek better lab miceQ93350912
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.Q34417339
Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse modelsQ34418781
Neuroinflammation and neuronal loss precede Aβ plaque deposition in the hAPP-J20 mouse model of Alzheimer's disease.Q34656208
Competitive short-term and long-term memory processes in spatial habituationQ34898346
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A fresh perspective from immunologists and vaccine researchers: active vaccination strategies to prevent and reverse Alzheimer's diseaseQ36240389
Immunization with Small Amyloid-β-derived Cyclopeptide Conjugates Diminishes Amyloid-β-Induced Neurodegeneration in MiceQ37053799
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UB-311, a novel UBITh® amyloid β peptide vaccine for mild Alzheimer's diseaseQ42655652
Enoxaparin treatment administered at both early and late stages of amyloid β deposition improves cognition of APPswe/PS1dE9 mice with differential effects on brain Aβ levelsQ42987394
Beta-amyloid monomers are neuroprotective.Q43285309
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's diseaseQ47583762
Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's diseaseQ47839532
Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse modelQ48472347
Cognitive phenotyping of amyloid precursor protein transgenic J20 miceQ48752053
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectspatial memoryQ3560550
Alzheimer's diseaseQ11081
P304page(s)261-280
P577publication date2020-07-23
P1433published inJournal of Alzheimer's disease reportsQ96319946
P1476titleVaccination Prevented Short-Term Memory Loss, but Deteriorated Long-Term Spatial Memory in Alzheimer's Disease Mice, Independent of Amyloid-β Pathology
P478volume4