Autologous CD4 T Lymphocytes Modified with a Tat-Dependent, Virus-Specific Endoribonuclease Gene in HIV-Infected Individuals

scientific article published on 10 November 2020

Autologous CD4 T Lymphocytes Modified with a Tat-Dependent, Virus-Specific Endoribonuclease Gene in HIV-Infected Individuals is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YMTHE.2020.11.007
P698PubMed publication ID33186691

P50authorCarl H. JuneQ19277113
Simon F LaceyQ56978267
Bruce L. LevineQ85544154
P2093author name stringFang Chen
Dong H Lee
Jeffrey M Jacobson
Wei-Ting Hwang
Irina Kulikovskaya
Julie K Jadlowsky
Joseph A Fraietta
Gabriela Plesa
Hideto Chono
Alexander Dimitri
Chelsie Bartoszek
Elizabeth A Veloso
P2860cites workGene editing of CCR5 in autologous CD4 T cells of persons infected with HIVQ28235281
CD4(+) T Cells Modified by the Endoribonuclease MazF Are Safe and Can Persist in SHIV-infected Rhesus MacaquesQ28656393
In vivo safety and persistence of endoribonuclease gene-transduced CD4+ T cells in cynomolgus macaques for HIV-1 gene therapy modelQ28741350
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleasesQ29615069
RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphomaQ34121209
Decade-long safety and function of retroviral-modified chimeric antigen receptor T cellsQ35202343
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppressionQ36781531
Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeysQ37295534
An efficient large-scale retroviral transduction method involving preloading the vector into a RetroNectin-coated bag with low-temperature shakingQ39031463
Sustained inhibition of HIV-1 replication by conditional expression of the E. coli-derived endoribonuclease MazF in CD4+ T cellsQ39188427
Acquisition of HIV-1 resistance in T lymphocytes using an ACA-specific E. coli mRNA interferaseQ39677452
Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptorQ41410840
A bioassay for HIV-1 based on Env-CD4 interactionQ41717006
Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.Q41918232
Expression and characterization of the trans-activator of HTLV-III/LAV virusQ45831293
Retroviral and Lentiviral Safety Analysis of Gene-Modified T Cell Products and Infused HIV and Oncology PatientsQ45875400
Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing TherapeuticsQ57282212
Re-emergence of HIV after stopping therapyQ59060012
In vivo delivery of synthetic DNA-encoded antibodies induces broad HIV-1-neutralizing activityQ91164201
P577publication date2020-11-10
P1433published inMolecular TherapyQ15762400
P1476titleAutologous CD4 T Lymphocytes Modified with a Tat-Dependent, Virus-Specific Endoribonuclease Gene in HIV-Infected Individuals

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