Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.

scientific article published on 12 October 2017

Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1006613
P8608Fatcat IDrelease_hjhms27b5va4lnqlghc4oghrau
P932PMC publication ID5638568
P698PubMed publication ID29023549

P50authorSarah R AkkinaQ56978249
Simon F LaceyQ56978267
Ronald G CollmanQ79946690
Aimee PayneQ88045983
Rachel S LeibmanQ89613667
Colby R MaldiniQ89613670
Farida ShaheenQ89613673
Christoph T EllebrechtQ97303751
James L. RileyQ38641154
P2093author name stringMichael C Holmes
Yanjie Yi
Jianbin Wang
Max W Richardson
Anthony J Secreto
Irina Kulikovskaya
Keith A Dufendach
Joshua A Glover
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4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T cellsQ80139532
The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity.Q36408432
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Cell fusion mediated by interaction of a hybrid CD4.CD8 molecule with the human immunodeficiency virus type 1 envelope glycoprotein does occur after a long lag timeQ36654246
A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid TumorsQ36709308
HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem CellsQ36757040
Several CD4 domains can play a role in human immunodeficiency virus infection in cellsQ36797775
Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylationQ36845470
New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasmaQ36891848
Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alphaQ36949816
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Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T CellsQ40965523
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P304page(s)e1006613
P577publication date2017-10-12
P1433published inPLOS PathogensQ283209
P1476titleSupraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor
P478volume13

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